List of works - Ruben Eggers

A compact dual promoter adeno-associated viral vector for efficient delivery of two genes to dorsal root ganglion neurons.

scientific article published on 28 November 2013

A multilevel screening strategy defines a molecular fingerprint of proregenerative olfactory ensheathing cells and identifies SCARB2, a protein that improves regenerative sprouting of injured sensory spinal axons

scientific journal article

A spatio-temporal analysis of motoneuron survival, axonal regeneration and neurotrophic factor expression after lumbar ventral root avulsion and implantation.

scientific article

Cellular toxicity following application of adeno-associated viral vector-mediated RNA interference in the nervous system

scientific article

Clinical and neurobiological advances in promoting regeneration of the ventral root avulsion lesion.

scientific article published on 28 September 2015

Comparison of AAV serotypes for gene delivery to dorsal root ganglion neurons

scientific article

Developing a potentially immunologically inert tetracycline-regulatable viral vector for gene therapy in the peripheral nerve

scientific article published on 3 April 2014

Differential effects of lentiviral vector-mediated overexpression of nerve growth factor and glial cell line-derived neurotrophic factor on regenerating sensory and motor axons in the transected peripheral nerve

scientific journal article

Enhanced regeneration and reinnervation following timed GDNF gene therapy in a cervical ventral root avulsion

scientific article published on 16 August 2019

From microsurgery to nanosurgery: how viral vectors may help repair the peripheral nerve.

scientific article published on January 2009

Gene therapy approaches to enhance regeneration of the injured peripheral nerve.

scientific article published on 18 July 2013

Gene transfer to the spinal cord neural scar with lentiviral vectors: predominant transgene expression in astrocytes but not in meningeal cells

scientific article published in November 2007

Genetic Deletion of the Transcriptional Repressor NFIL3 Enhances Axon Growth In Vitro but Not Axonal Repair In Vivo

scientific article published on 20 May 2015

Intravitreal injection of adeno-associated viral vectors results in the transduction of different types of retinal neurons in neonatal and adult rats: a comparison with lentiviral vectors.

scientific article published in September 2002

LLM3D: a log-linear modeling-based method to predict functional gene regulatory interactions from genome-wide expression data

scientific article

Lentiviral vector-mediated gradients of GDNF in the injured peripheral nerve: effects on nerve coil formation, Schwann cell maturation and myelination

scientific article

Long-term adeno-associated viral vector-mediated expression of truncated TrkB in the adult rat facial nucleus results in motor neuron degeneration.

scientific article published on February 2006

Modeling early Parkinson's disease pathology with chronic low dose MPTP treatment

scientific article published in January 2013

Neuroregenerative effects of lentiviral vector-mediated GDNF expression in reimplanted ventral roots

scientific article

Noninvasive bioluminescence imaging of olfactory ensheathing glia and schwann cells following transplantation into the lesioned rat spinal cord

scientific article published on 22 March 2012

Repulsive guidance molecule a (RGMa) induces neuropathological and behavioral changes that closely resemble Parkinson's disease.

scientific article published on 21 August 2017

Rescue and sprouting of motoneurons following ventral root avulsion and reimplantation combined with intraspinal adeno-associated viral vector-mediated expression of glial cell line-derived neurotrophic factor or brain-derived neurotrophic factor.

scientific article published on October 2004

Schwann cells transduced with a lentiviral vector encoding Fgf-2 promote motor neuron regeneration following sciatic nerve injury

scientific article published on 2 July 2014

The proliferative capacity of the subventricular zone is maintained in the parkinsonian brain

scientific article published on 01 November 2011

List of works by Ruben Eggers

A compact dual promoter adeno-associated viral vector for efficient delivery of two genes to dorsal root ganglion neurons.

A multilevel screening strategy defines a molecular fingerprint of proregenerative olfactory ensheathing cells and identifies SCARB2, a protein that improves regenerative sprouting of injured sensory spinal axons

A spatio-temporal analysis of motoneuron survival, axonal regeneration and neurotrophic factor expression after lumbar ventral root avulsion and implantation.

Cellular toxicity following application of adeno-associated viral vector-mediated RNA interference in the nervous system

Clinical and neurobiological advances in promoting regeneration of the ventral root avulsion lesion.

Comparison of AAV serotypes for gene delivery to dorsal root ganglion neurons

Developing a potentially immunologically inert tetracycline-regulatable viral vector for gene therapy in the peripheral nerve

Differential effects of lentiviral vector-mediated overexpression of nerve growth factor and glial cell line-derived neurotrophic factor on regenerating sensory and motor axons in the transected peripheral nerve

Enhanced regeneration and reinnervation following timed GDNF gene therapy in a cervical ventral root avulsion

From microsurgery to nanosurgery: how viral vectors may help repair the peripheral nerve.

Gene therapy approaches to enhance regeneration of the injured peripheral nerve.

Gene transfer to the spinal cord neural scar with lentiviral vectors: predominant transgene expression in astrocytes but not in meningeal cells

Genetic Deletion of the Transcriptional Repressor NFIL3 Enhances Axon Growth In Vitro but Not Axonal Repair In Vivo

Intravitreal injection of adeno-associated viral vectors results in the transduction of different types of retinal neurons in neonatal and adult rats: a comparison with lentiviral vectors.

LLM3D: a log-linear modeling-based method to predict functional gene regulatory interactions from genome-wide expression data

Lentiviral vector-mediated gradients of GDNF in the injured peripheral nerve: effects on nerve coil formation, Schwann cell maturation and myelination

Long-term adeno-associated viral vector-mediated expression of truncated TrkB in the adult rat facial nucleus results in motor neuron degeneration.

Modeling early Parkinson's disease pathology with chronic low dose MPTP treatment

Neuroregenerative effects of lentiviral vector-mediated GDNF expression in reimplanted ventral roots

Noninvasive bioluminescence imaging of olfactory ensheathing glia and schwann cells following transplantation into the lesioned rat spinal cord

Repulsive guidance molecule a (RGMa) induces neuropathological and behavioral changes that closely resemble Parkinson's disease.

Rescue and sprouting of motoneurons following ventral root avulsion and reimplantation combined with intraspinal adeno-associated viral vector-mediated expression of glial cell line-derived neurotrophic factor or brain-derived neurotrophic factor.

Schwann cells transduced with a lentiviral vector encoding Fgf-2 promote motor neuron regeneration following sciatic nerve injury

The proliferative capacity of the subventricular zone is maintained in the parkinsonian brain