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List of works by Barbara Gatto

2,6-Di(omega-aminoalkyl)-2,5,6,7-tetrahydropyrazolo[3,4,5-mn]pyrimido[5,6,1-de]acridine-5,7-diones: novel, potent, cytotoxic, and DNA-binding agents

scientific article published in January 2002

6-Aminoquinolones as new potential anti-HIV agents.

scientific article

Anthracyclines: recent developments in their separation and quantitation

scientific article

Antiviral 6-amino-quinolones: molecular basis for potency and selectivity

scientific article published in October 2005

Behind the Mirror: Chirality Tunes the Reactivity and Cytotoxicity of Chloropiperidines as Potential Anticancer Agents

scientific article published on 13 February 2019

Bis-3-chloropiperidines containing bridging lysine linkers: Influence of side chain structure on DNA alkylating activity

scientific article published on 7 February 2015

Clerocidin alkylates DNA through its epoxide function: evidence for a fine tuned mechanism of action.

scientific article

Clerocidin interacts with the cleavage complex of Streptococcus pneumoniae topoisomerase IV to induce selective irreversible DNA damage

scientific article published on 13 April 2006

Coralyne and related compounds as mammalian topoisomerase I and topoisomerase II poisons.

scientific article published on June 1996

Design, synthesis, and biological properties of new bis(acridine-4-carboxamides) as anticancer agents

scientific article published in July 2003

Development and Optimization of a Thrombin Sandwich Aptamer Microarray

scientific article published on 8 August 2012

Differential Poisoning of Topoisomerases by Menogaril and Nogalamycin Dictated by the Minor Groove-Binding Nogalose Sugar†

scientific article published on 01 October 1997

Direct and Topoisomerase II Mediated DNA Damage by Bis-3-chloropiperidines: The Importance of Being an Earnest G.

scientific article

Drugs acting on the beta isoform of human topoisomerase II (p180).

scientific article

Effective DNA inhibitors of cathepsin g by in vitro selection

scientific article published on 20 June 2008

Effects of common buffer systems on drug activity: the case of clerocidin.

scientific article

Ellagic Acid and Polyhydroxylated Urolithins Are Potent Catalytic Inhibitors of Human Topoisomerase II: An in Vitro Study

Enzymatic formation of PEGylated oligonucleotides

scientific article published on 03 February 2014

From proteins to nucleic acid-based drugs: the role of biotech in anti-VEGF therapy.

scientific article published on July 2006

Human thrombin detection through a sandwich aptamer microarray: interaction analysis in solution and in solid phase

scientific article

Identification of novel 2-benzoxazolinone derivatives with specific inhibitory activity against the HIV-1 nucleocapsid protein

scientific article published on 24 December 2017

In vitro selection of DNA aptamers that bind L-tyrosinamide

scientific article

Indenocinnoline derivatives as G-quadruplex binders, topoisomerase IIα inhibitors and antiproliferative agents

scientific article published on 11 March 2017

Inhibition of human immunodeficiency virus type 1 tat-trans-activation-responsive region interaction by an antiviral quinolone derivative

scientific article published on May 2004

Inhibition of subgenomic hepatitis C virus RNA replication by acridone derivatives: identification of an NS3 helicase inhibitor

scientific article published on May 2009

Involvement of p53 in specific anti-neuroectodermal tumor activity of aloe-emodin ⬇️

scientific article published in October 2003

Mapping drug interactions at the covalent topoisomerase II-DNA complex by bisantrene/amsacrine congeners.

scientific article published on May 1998

Mechanisms of HIV-1 Nucleocapsid Protein Inhibition by Lysyl-Peptidyl-Anthraquinone Conjugates

scientific article

Mg 2+ -mediated binding of 6-Substituted quinolones to DNA: relevance to biological activity

scientific article published on 01 September 1998

Monoclonal antibodies in cancer therapy.

scientific article published in September 2004

Non-Natural Linker Configuration in 2,6-Dipeptidyl-Anthraquinones Enhances the Inhibition of TAR RNA Binding/Annealing Activities by HIV-1 NC and Tat Proteins.

scientific article

Novel pyrrolo[3,2-f]quinolines: synthesis and antiproliferative activity

scientific article

Nucleocapsid Annealing-Mediated Electrophoresis (NAME) assay allows the rapid identification of HIV-1 nucleocapsid inhibitors

scientific article

On the mechanism of action of quinolone drugs

scientific article published on 01 September 1993

Peptidyl Anthraquinones as Potential Antineoplastic Drugs: Synthesis, DNA Binding, Redox Cycling, and Biological Activity

scientific article published on 01 August 1996

Perylene side chains modulate G-quadruplex conformation in biologically relevant DNA sequences

scientific article published on 31 August 2008

Preferred interaction of d-peptidyl-anthraquinones with double-stranded B-DNA

scientific article published on 01 December 1997

Pyrrolo-quinoline derivatives as potential antineoplastic drugs

scientific article published on 01 June 2000

Quantitation of camptothecin and related compounds

scientific article (publication date: November 2001)

Quinolino[3,4-b]quinoxalines and pyridazino[4,3-c]quinoline derivatives: Synthesis, inhibition of topoisomerase IIα, G-quadruplex binding and cytotoxic properties.

scientific article published on 28 July 2016

Rational design, synthesis, and DNA binding properties of novel sequence-selective peptidyl congeners of ametantrone.

scientific article published on July 2010

Sequence-specific interactions of drugs interfering with the topoisomerase-DNA cleavage complex

scientific article

Studies of anti-HIV transcription inhibitor quinolones: identification of potent N1-vinyl derivatives

scientific article published on November 2010

Synthesis and DNA cleavage activity of Bis-3-chloropiperidines as alkylating agents

scientific article published on 11 March 2014

Synthesis and Evaluation of Terbenzimidazoles as Topoisomerase I Inhibitors ⬇️

scientific article published on September 1, 1995

Synthesis and biological evaluation of 2-phenylquinolones targeted at Tat/TAR recognition.

scientific article

Synthesis and evaluation of a bis-3-chloropiperidine derivative incorporating an anthraquinone pharmacophore

scientific article published on 20 August 2015

Synthesis and in Vitro Screening of New Series of 2,6-Dipeptidyl-anthraquinones: Influence of Side Chain Length on HIV-1 Nucleocapsid Inhibitors.

scientific article published on 22 January 2016

The evolving world of protein-G-quadruplex recognition: a medicinal chemist's perspective.

scientific article published on 29 April 2011

Virtual Cross-Linking of the Active Nemorubicin Metabolite PNU-159682 to Double-Stranded DNA.

scientific article published on 9 January 2017

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