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List of works by Kevin G Hardwick

A novel protein phosphatase 1-dependent spindle checkpoint silencing mechanism

scientific article published on 9 July 2009

Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption.

scientific article

An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombe

scientific article published on 15 November 2009

Analysis of Bub3 spindle checkpoint function in Xenopus egg extracts

scientific article published in February 2003

Bub1 and the multilayered inhibition of Cdc20-APC/C in mitosis

scientific article

Bub1 is a fission yeast kinetochore scaffold protein, and is sufficient to recruit other spindle checkpoint proteins to ectopic sites on chromosomes

scientific article

Bub1 kinase targets Sgo1 to ensure efficient chromosome biorientation in budding yeast mitosis

scientific article

Bub3p facilitates spindle checkpoint silencing in fission yeast

scientific article published on December 2009

Budding yeast Cdc20: a target of the spindle checkpoint.

scientific article

CPF-associated phosphatase activity opposes condensin-mediated chromosome condensation

scientific article

Cdc28 activates exit from mitosis in budding yeast.

scientific article published in June 2000

Checkpoint signalling: Mad2 conformers and signal propagation

scientific article (publication date: 22 February 2005)

Comment on "A centrosome-independent role for gamma-TuRC proteins in the spindle assembly checkpoint"

scientific article published on May 2007

Control of Shugoshin function during fission-yeast meiosis

scientific article published in December 2005

Correction: Mps1Mph1 Kinase Phosphorylates Mad3 to Inhibit Cdc20Slp1-APC/C and Maintain Spindle Checkpoint Arrests

scientific article published on 21 April 2016

Distinct chromosome segregation roles for spindle checkpoint proteins

scientific article

Dss1 is a 26S proteasome ubiquitin receptor

scientific article published on 9 October 2014

ERS1 a seven transmembrane domain protein from Saccharomyces cerevisiae

scientific article

Fission Yeast Apc15 Stabilizes MCC-Cdc20-APC/C Complexes, Ensuring Efficient Cdc20 Ubiquitination and Checkpoint Arrest

scientific article published on 28 March 2017

Fission yeast Mad3p is required for Mad2p to inhibit the anaphase-promoting complex and localizes to kinetochores in a Bub1p-, Bub3p-, and Mph1p-dependent manner

scientific article published on April 2002

Fission yeast bub1 is a mitotic centromere protein essential for the spindle checkpoint and the preservation of correct ploidy through mitosis

scientific article

Generation of a Spindle Checkpoint Arrest from Synthetic Signaling Assemblies

scientific article

Genes that allow yeast cells to grow in the absence of the HDEL receptor ⬇️

scientific article published on November 1, 1992

Getting down to the phosphorylated 'nuts and bolts' of spindle checkpoint signalling

scientific article published on 15 October 2009

Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function

scientific article published on 22 February 2014

Identification of a Sgo2-Dependent but Mad2-Independent Pathway Controlling Anaphase Onset in Fission Yeast

scientific article

Ipl1p-dependent phosphorylation of Mad3p is required for the spindle checkpoint response to lack of tension at kinetochores.

scientific article

Kinase activity of fission yeast Mph1 is required for Mad2 and Mad3 to stably bind the anaphase promoting complex

scientific article published on 25 January 2012

Kindlin-1 regulates mitotic spindle formation by interacting with integrins and Plk-1.

scientific article published on January 2013

Kinetochore targeting of fission yeast Mad and Bub proteins is essential for spindle checkpoint function but not for all chromosome segregation roles of Bub1p

scientific article

Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast

scientific article

Mad3 KEN boxes mediate both Cdc20 and Mad3 turnover, and are critical for the spindle checkpoint

scientific article

Mps1Mph1 Kinase Phosphorylates Mad3 to Inhibit Cdc20Slp1-APC/C and Maintain Spindle Checkpoint Arrests

scientific article published on 16 February 2016

Novel sfi1 alleles uncover additional functions for Sfi1p in bipolar spindle assembly and function

scientific article

Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase B

scientific article (publication date: December 2011)

Overcoming inhibition in the spindle checkpoint

scientific article published on December 2009

Phosphodependent recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 kinase maintains the spindle checkpoint.

scientific article published on 19 April 2012

Regulated reconstitution of spindle checkpoint arrest and silencing through chemically induced dimerisation

scientific article published on 04 October 2018

SED5 encodes a 39-kD integral membrane protein required for vesicular transport between the ER and the Golgi complex ⬇️

scientific article published on November 1, 1992

SED6 is identical to ERG6, and encodes a putative methyltransferase required for ergosterol synthesis

scientific article published in February 1994

Shugoshin 2 regulates localization of the chromosomal passenger proteins in fission yeast mitosis

scientific article published on 14 February 2007

Sorting of soluble ER proteins in yeast

scientific article

Spindle checkpoint silencing requires association of PP1 to both Spc7 and kinesin-8 motors.

scientific article published on June 2011

Spindle checkpoint silencing: ensuring rapid and concerted anaphase onset

scientific article

The A78V mutation in the Mad3-like domain of Schizosaccharomyces pombe Bub1p perturbs nuclear accumulation and kinetochore targeting of Bub1p, Bub3p, and Mad3p and spindle assembly checkpoint function

scientific article

The CENP-A N-tail confers epigenetic stability to centromeres via the CENP-T branch of the CCAN in fission yeast

scientific article

The Complexity of Bub1 Regulation: Phosphorylation, Phosphorylation, Phosphorylation

scientific article published on 01 March 2003

The awesome power of multiple model systems: interpreting the complex nature of spindle checkpoint signaling

scientific article

The spindle checkpoint

scientific article published on 01 October 2006

The spindle checkpoint functions of Mad3 and Mad2 depend on a Mad3 KEN box-mediated interaction with Cdc20-anaphase-promoting complex (APC/C).

scientific article published on 13 June 2008

The spindle checkpoint: assays for the analysis of spindle checkpoint arrest and recovery

scientific article published in January 2009

The spindle checkpoint: how do cells delay anaphase onset?

scientific article published on January 2008

The spindle checkpoint: structural insights into dynamic signalling

scientific article

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