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List of works by Rowan Hardy

11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis

scientific article published in August 2018

11β-HSD1 plays a critical role in trabecular bone loss associated with systemic glucocorticoid therapy

scientific article published on 16 August 2019

11β-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation ⬇️

scientific article published on 31 August 2016

Adrenal gland and bone.

scientific article published on 11 June 2010

Cerebral Oxidative Stress and Microvasculature Defects in TNF-α Expressing Transgenic and Porphyromonas gingivalis-Infected ApoE-/- Mice.

scientific article published on 8 August 2017

Characterisation of fibroblast-like synoviocytes from a murine model of joint inflammation ⬇️

scientific article published on 29 January 2013

DKK1 expression by synovial fibroblasts in very early rheumatoid arthritis associates with lymphocyte adhesion in an in vitro flow co-culture system

scientific article

Deletion of mesenchymal glucocorticoid receptor attenuates embryonic lung development and abdominal wall closure.

scientific article

Differential expression, function and response to inflammatory stimuli of 11beta-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation ⬇️

scientific article published on January 2006

Differential glucocorticoid metabolism in patients with persistent versus resolving inflammatory arthritis ⬇️

scientific article published on 14 May 2015

Exploring the Interface between Inflammatory and Therapeutic Glucocorticoid Induced Bone and Muscle Loss

scientific article published on 16 November 2019

Expression of 11β-hydroxysteroid dehydrogenase enzymes in human osteosarcoma: potential role in pathogenesis and as targets for treatments

scientific article

Glucocorticoid activation by 11β-hydroxysteroid dehydrogenase enzymes in relation to inflammation and glycaemic control in chronic kidney disease: a cross-sectional study

scientific article published on 15 November 2018

Glucocorticoid metabolism in rheumatoid arthritis.

scientific article published on March 2014

Glucocorticoid-induced osteoporosis - a disorder of mesenchymal stromal cells?

scientific article

Glucocorticoids and Bone: Consequences of Endogenous and Exogenous Excess and Replacement Therapy

scientific article published on 13 June 2018

Inflammatory regulation of glucocorticoid metabolism in mesenchymal stromal cells ⬇️

scientific article published on July 2012

Local and systemic glucocorticoid metabolism in inflammatory arthritis ⬇️

scientific article published on 17 April 2008

Local steroid activation is a critical mediator of the anti-inflammatory actions of therapeutic glucocorticoids

scientific article published on 08 November 2020

Localization, Age- and Site-Dependent Expression, and Regulation of 11β-Hydroxysteroid Dehydrogenase Type 1 in Skin

scientific article published in January 2011

Synergistic induction of local glucocorticoid generation by inflammatory cytokines and glucocorticoids: implications for inflammation associated bone loss. ⬇️

scientific article published on 22 June 2009

Synovial DKK1 expression is regulated by local glucocorticoid metabolism in inflammatory arthritis ⬇️

scientific article published on 18 October 2012

TNFα depleting therapy improves fertility and animal welfare in TNFα-driven transgenic models of polyarthritis when administered in their routine breeding

scientific article published in January 2017

Targeting 11β-hydroxysteroid dehydrogenases: a novel approach to manipulating local glucocorticoid levels with implications for rheumatic disease

scientific article published on 26 March 2013

The 11beta-hydroxysteroid dehydrogenase enzymes--arbiters of the effects of glucocorticoids in synovium and bone

scientific article published on 15 July 2010

Therapeutic glucocorticoids prevent bone loss but drive muscle wasting when administered in chronic polyarthritis

scientific article published on 01 August 2019

Therapeutic glucocorticoids: mechanisms of actions in rheumatic diseases

scientific article published on 07 February 2020

Unravelling how glucocorticoids work in rheumatoid arthritis

scientific article published on 01 October 2018

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