List of works - Claudio Da Cunha

A simple and fast densitometric method for the analysis of tyrosine hydroxylase immunoreactivity in the substantia nigra pars compacta and in the ventral tegmental area

scientific article published on 28 November 2005

Activation of postsynaptic D2 dopamine receptors in the rat dorsolateral striatum prevents the amnestic effect of systemically administered neuroleptics.

scientific article published on 26 December 2014

Amino acid and monoamine alterations in the cerebral cortex and hippocampus of mice submitted to ricinine-induced seizures.

scientific article

Amphetamine and pentylenetetrazole given post-trial 1 enhance one-trial tolerance to the anxiolytic effect of diazepam in the elevated plus-maze in mice.

scientific article published on 7 July 2006

Antagonistic interaction between adenosine A2A and dopamine D2 receptors modulates the social recognition memory in reserpine-treated rats

scientific article published in July 2005

Antidepressant-like effect of celecoxib piroxicam in rat models of depression

scientific article

Antidepressant-like effect of the novel MAO inhibitor 2-(3,4-dimethoxy-phenyl)-4,5-dihydro-1H-imidazole (2-DMPI) in mice

scientific article published on 17 April 2012

Anxiety-like behavior induced by 6-OHDA animal model of Parkinson's disease may be related to a dysregulation of neurotransmitter systems in brain areas related to anxiety

scientific article published on 26 May 2019

Anxiogenic effects of the intraamygdala injection of flumazenil, a benzodiazepine receptor antagonist

scientific article published on September 1, 1992

Behavioral, neurochemical and histological alterations promoted by bilateral intranigral rotenone administration: a new approach for an old neurotoxin.

scientific article

Behavioural and neurochemical effects of phosphatidylserine in MPTP lesion of the substantia nigra of rats.

scientific article published in January 2004

Benzodiazepines in the brain. Their origin and possible biological roles

scientific article published on January 1, 1992

Both the dorsal hippocampus and the dorsolateral striatum are needed for rat navigation in the Morris water maze

scientific article published on 12 September 2011

Cellular prion protein (PrP(C)) modulates ethanol-induced behavioral adaptive changes in mice.

scientific article published on 26 June 2014

Cellular prion protein is present in dopaminergic neurons and modulates the dopaminergic system

scientific article published on 26 April 2014

Comparison of bilaterally 6-OHDA- and MPTP-lesioned rats as models of the early phase of Parkinson's disease: histological, neurochemical, motor and memory alterations

scientific article published on 6 June 2005

Decreased synaptic plasticity in the medial prefrontal cortex underlies short-term memory deficits in 6-OHDA-lesioned rats

scientific article

Diazepam Inhibits Electrically Evoked and Tonic Dopamine Release in the Nucleus Accumbens and Reverses the Effect of Amphetamine

scientific article published on 30 December 2016

Diazepam blocks 50 kHz ultrasonic vocalizations and stereotypies but not the increase in locomotor activity induced in rats by amphetamine

scientific article published on 23 March 2018

Dopaminergic D2 receptor is a key player in the substantia nigra pars compacta neuronal activation mediated by REM sleep deprivation

scientific article

Effect of post-training injections of flumazenil into the amygdala, hippocampus and septum on retention of habituation and of inhibitory avoidance in rats

scientific article published on January 1, 1991

Effect of various training procedures on performance in an elevated plus-maze: possible relation with brain regional levels of benzodiazepine-like molecules

scientific article published on November 1, 1992

Effects of SR141716A on Cognitive and Depression-Related Behavior in an Animal Model of Premotor Parkinson's Disease.

scientific article published on 26 September 2010

Effects of caffeine on learning and memory in rats tested in the Morris water maze.

scientific article

Effects of environmentally relevant concentrations of the anti-inflammatory drug diclofenac in freshwater fish Rhamdia quelen.

scientific article published on 3 February 2017

Effects of ventrolateral striatal inactivation on predatory hunting.

scientific article

Emotional, cognitive and neurochemical alterations in a premotor stage model of Parkinson's disease.

scientific article published on 9 September 2008

Ethanol exposure history and alcoholic reward differentially alter dopamine release in the nucleus accumbens to a reward-predictive cue.

scientific article published on 30 March 2018

Evaluation of the face validity of reserpine administration as an animal model of depression--Parkinson's disease association.

scientific article published in June 2002

Evidence for the substantia nigra pars compacta as an essential component of a memory system independent of the hippocampal memory system.

scientific article

Evidence that conditioned avoidance responses are reinforced by positive prediction errors signaled by tonic striatal dopamine.

scientific article published on 3 July 2012

Exercise Improves Cognitive Impairment and Dopamine Metabolism in MPTP-Treated Mice

scientific article

Failure of estrogen to protect the substantia nigra pars compacta of female rats from lesion induced by 6-hydroxydopamine.

scientific article published in October 2003

Functional disconnection of the substantia nigra pars compacta from the pedunculopontine nucleus impairs learning of a conditioned avoidance task

scientific article

Habituation and inhibitory avoidance training alter brain regional levels of benzodiazepine-like molecules and are affected by intracerebral flumazenil microinjection.

scientific article published in May 1991

Hemiparkinsonian rats rotate toward the side with the weaker dopaminergic neurotransmission

scientific article published on 5 February 2008

Induction of depressive-like behavior by intranigral 6-OHDA is directly correlated with deficits in striatal dopamine and hippocampal serotonin

scientific article published on 30 October 2013

Intranigral LPS administration produces dopamine, glutathione but not behavioral impairment in comparison to MPTP and 6-OHDA neurotoxin models of Parkinson's disease

scientific article published on 26 June 2010

Involvement of mast cells in a mouse model of postoperative pain

scientific article

Is the unilateral lesion of the left substantia nigra pars compacta sufficient to induce working memory impairment in rats?

scientific article published in September 2004

Learning processing in the basal ganglia: a mosaic of broken mirrors

scientific article published on 11 October 2008

Lesion of the substantia nigra, pars compacta impairs delayed alternation in a Y-maze in rats.

scientific article published in March 2005

Memory facilitation by post-training intraperitoneal, intracerebroventricular and intra-amygdala injection of Ro 5-4864.

scientific article published on March 1991

Memory impairment induced by sodium fluoride is associated with changes in brain monoamine levels.

scientific article published on 3 December 2009

Microdialysis study of striatal dopamine in MPTP-hemilesioned rats challenged with apomorphine and amphetamine.

scientific article published on July 2010

Modulatory effect of nano TiO₂on Pb in Hoplias malabaricus trophically exposed.

scientific article published on 29 May 2014

Multiple intranigral unilateral LPS infusion protocol generates a persistent cognitive impairment without cumulative dopaminergic impairment

scientific article published in November 2013

Neuroprotective effects of peroxisome proliferator-activated receptor alpha and gamma agonists in model of parkinsonism induced by intranigral 1-methyl-4-phenyl-1,2,3,6-tetrahyropyridine

scientific article published on 13 August 2014

Neurotransmitter receptors involved in post-training memory processing by the amygdala, medial septum, and hippocampus of the rat

scientific article published on July 1, 1992

Nicotine induces sensitization of turning behavior in 6-hydroxydopamine lesioned rats.

scientific article published on 18 March 2009

Olfactory impairment in the rotenone model of Parkinson's disease is associated with bulbar dopaminergic D2 activity after REM sleep deprivation.

scientific article published on December 2014

Oscillations in cortico-basal ganglia circuits: implications for Parkinson's disease and other neurologic and psychiatric conditions

scientific article published on 01 May 2019

PPAR-α agonist fenofibrate protects against the damaging effects of MPTP in a rat model of Parkinson's disease.

scientific article

Paracetamol causes endocrine disruption and hepatotoxicity in male fish Rhamdia quelen after subchronic exposure.

scientific article published on 8 May 2017

Partial lesion of dopamine neurons of rat substantia nigra impairs conditioned place aversion but spares conditioned place preference.

scientific article published on 6 March 2017

Pharmacological evaluation of ricinine, a central nervous system stimulant isolated from Ricinus communis.

scientific article

Phosphatidylserine reverses reserpine-induced amnesia.

scientific article published in September 2000

Place learning strategy of substantia nigra pars compacta-lesioned rats

scientific article

Post-Training Memory Processing in Amygdala, Septum and Hippocampus: Role of Benzodiazepine/GABAA Receptors, and their Interaction with other Neurotransmitter Systems ⬇️

scientific article published on January 1, 1992

Pre-training to find a hidden platform in the Morris water maze can compensate for a deficit to find a cued platform in a rat model of Parkinson's disease

scientific article

Putative role of monoamines in the antidepressant-like mechanism induced by striatal MT2 blockade

scientific article published on 9 September 2014

REM sleep deprivation generates cognitive and neurochemical disruptions in the intranigral rotenone model of Parkinson's disease

scientific article published in August 2013

REM sleep deprivation reverses neurochemical and other depressive-like alterations induced by olfactory bulbectomy

scientific article

Role of brainstem serotonin in analgesia produced by low-intensity exercise on neuropathic pain after sciatic nerve injury in mice

scientific article

Roles of D1-like dopamine receptors in the nucleus accumbens and dorsolateral striatum in conditioned avoidance responses

scientific article published in July 2011

Selegiline reverses aβ₂₅₋₃₅-induced cognitive deficit in male mice.

scientific article published on 5 September 2013

Special issue on the role of the basal ganglia in learning and memory. Preface

scientific article published on 30 December 2008

Spironolactone and low-dose dexamethasone enhance extinction of contextual fear conditioning.

scientific article published on 3 July 2010

Subchronic fluoride intake induces impairment in habituation and active avoidance tasks in rats.

scientific article published on 25 October 2007

The "anxiety state" and its relation with rat models of memory and habituation.

scientific article published on September 1999

The COX-2 inhibitor parecoxib produces neuroprotective effects in MPTP-lesioned rats.

scientific article published on 19 January 2007

The brain decade in debate: III. Neurobiology of emotion.

scientific article

The effect of caffeine in animal models of learning and memory

scientific article

The lesion of the rat substantia nigra pars compacta dopaminergic neurons as a model for Parkinson's disease memory disabilities.

scientific article

The mechanism of antidepressant-like effects of piroxicam in rats.

scientific article

The nonsteroidal antiinflammatory drug piroxicam reverses the onset of depressive-like behavior in 6-OHDA animal model of Parkinson's disease.

scientific article published on 18 May 2015

The role of nucleus accumbens and dorsolateral striatal D2 receptors in active avoidance conditioning.

scientific article published on 17 May 2011

The role of the basal ganglia in motivated behavior

scientific article

The role of the ventrolateral caudoputamen in predatory hunting.

scientific article published on 28 October 2011

The roles of the nucleus accumbens core, dorsomedial striatum, and dorsolateral striatum in learning: performance and extinction of Pavlovian fear-conditioned responses and instrumental avoidance responses.

scientific article published on 26 November 2013

Toward sophisticated basal ganglia neuromodulation: Review on basal ganglia deep brain stimulation

scientific article

Unraveling a new circuitry for sleep regulation in Parkinson's disease

scientific article published on 15 April 2016

List of works by Claudio Da Cunha

A simple and fast densitometric method for the analysis of tyrosine hydroxylase immunoreactivity in the substantia nigra pars compacta and in the ventral tegmental area

Activation of postsynaptic D2 dopamine receptors in the rat dorsolateral striatum prevents the amnestic effect of systemically administered neuroleptics.

Amino acid and monoamine alterations in the cerebral cortex and hippocampus of mice submitted to ricinine-induced seizures.

Amphetamine and pentylenetetrazole given post-trial 1 enhance one-trial tolerance to the anxiolytic effect of diazepam in the elevated plus-maze in mice.

Antagonistic interaction between adenosine A2A and dopamine D2 receptors modulates the social recognition memory in reserpine-treated rats

Antidepressant-like effect of celecoxib piroxicam in rat models of depression

Antidepressant-like effect of the novel MAO inhibitor 2-(3,4-dimethoxy-phenyl)-4,5-dihydro-1H-imidazole (2-DMPI) in mice

Anxiety-like behavior induced by 6-OHDA animal model of Parkinson's disease may be related to a dysregulation of neurotransmitter systems in brain areas related to anxiety

Anxiogenic effects of the intraamygdala injection of flumazenil, a benzodiazepine receptor antagonist

Behavioral, neurochemical and histological alterations promoted by bilateral intranigral rotenone administration: a new approach for an old neurotoxin.

Behavioural and neurochemical effects of phosphatidylserine in MPTP lesion of the substantia nigra of rats.

Benzodiazepines in the brain. Their origin and possible biological roles

Both the dorsal hippocampus and the dorsolateral striatum are needed for rat navigation in the Morris water maze

Cellular prion protein (PrP(C)) modulates ethanol-induced behavioral adaptive changes in mice.

Cellular prion protein is present in dopaminergic neurons and modulates the dopaminergic system

Comparison of bilaterally 6-OHDA- and MPTP-lesioned rats as models of the early phase of Parkinson's disease: histological, neurochemical, motor and memory alterations

Decreased synaptic plasticity in the medial prefrontal cortex underlies short-term memory deficits in 6-OHDA-lesioned rats

Diazepam Inhibits Electrically Evoked and Tonic Dopamine Release in the Nucleus Accumbens and Reverses the Effect of Amphetamine

Diazepam blocks 50 kHz ultrasonic vocalizations and stereotypies but not the increase in locomotor activity induced in rats by amphetamine

Dopaminergic D2 receptor is a key player in the substantia nigra pars compacta neuronal activation mediated by REM sleep deprivation

Effect of post-training injections of flumazenil into the amygdala, hippocampus and septum on retention of habituation and of inhibitory avoidance in rats

Effect of various training procedures on performance in an elevated plus-maze: possible relation with brain regional levels of benzodiazepine-like molecules

Effects of SR141716A on Cognitive and Depression-Related Behavior in an Animal Model of Premotor Parkinson's Disease.

Effects of caffeine on learning and memory in rats tested in the Morris water maze.

Effects of environmentally relevant concentrations of the anti-inflammatory drug diclofenac in freshwater fish Rhamdia quelen.

Effects of ventrolateral striatal inactivation on predatory hunting.

Emotional, cognitive and neurochemical alterations in a premotor stage model of Parkinson's disease.

Ethanol exposure history and alcoholic reward differentially alter dopamine release in the nucleus accumbens to a reward-predictive cue.

Evaluation of the face validity of reserpine administration as an animal model of depression--Parkinson's disease association.

Evidence for the substantia nigra pars compacta as an essential component of a memory system independent of the hippocampal memory system.

Evidence that conditioned avoidance responses are reinforced by positive prediction errors signaled by tonic striatal dopamine.

Exercise Improves Cognitive Impairment and Dopamine Metabolism in MPTP-Treated Mice

Failure of estrogen to protect the substantia nigra pars compacta of female rats from lesion induced by 6-hydroxydopamine.

Functional disconnection of the substantia nigra pars compacta from the pedunculopontine nucleus impairs learning of a conditioned avoidance task

Habituation and inhibitory avoidance training alter brain regional levels of benzodiazepine-like molecules and are affected by intracerebral flumazenil microinjection.

Hemiparkinsonian rats rotate toward the side with the weaker dopaminergic neurotransmission

Induction of depressive-like behavior by intranigral 6-OHDA is directly correlated with deficits in striatal dopamine and hippocampal serotonin

Intranigral LPS administration produces dopamine, glutathione but not behavioral impairment in comparison to MPTP and 6-OHDA neurotoxin models of Parkinson's disease

Involvement of mast cells in a mouse model of postoperative pain

Is the unilateral lesion of the left substantia nigra pars compacta sufficient to induce working memory impairment in rats?

Learning processing in the basal ganglia: a mosaic of broken mirrors

Lesion of the substantia nigra, pars compacta impairs delayed alternation in a Y-maze in rats.

Memory facilitation by post-training intraperitoneal, intracerebroventricular and intra-amygdala injection of Ro 5-4864.

Memory impairment induced by sodium fluoride is associated with changes in brain monoamine levels.

Microdialysis study of striatal dopamine in MPTP-hemilesioned rats challenged with apomorphine and amphetamine.

Modulatory effect of nano TiO₂on Pb in Hoplias malabaricus trophically exposed.

Multiple intranigral unilateral LPS infusion protocol generates a persistent cognitive impairment without cumulative dopaminergic impairment

Neuroprotective effects of peroxisome proliferator-activated receptor alpha and gamma agonists in model of parkinsonism induced by intranigral 1-methyl-4-phenyl-1,2,3,6-tetrahyropyridine

Neurotransmitter receptors involved in post-training memory processing by the amygdala, medial septum, and hippocampus of the rat

Nicotine induces sensitization of turning behavior in 6-hydroxydopamine lesioned rats.

Olfactory impairment in the rotenone model of Parkinson's disease is associated with bulbar dopaminergic D2 activity after REM sleep deprivation.

Oscillations in cortico-basal ganglia circuits: implications for Parkinson's disease and other neurologic and psychiatric conditions

PPAR-α agonist fenofibrate protects against the damaging effects of MPTP in a rat model of Parkinson's disease.

Paracetamol causes endocrine disruption and hepatotoxicity in male fish Rhamdia quelen after subchronic exposure.

Partial lesion of dopamine neurons of rat substantia nigra impairs conditioned place aversion but spares conditioned place preference.

Pharmacological evaluation of ricinine, a central nervous system stimulant isolated from Ricinus communis.

Phosphatidylserine reverses reserpine-induced amnesia.

Place learning strategy of substantia nigra pars compacta-lesioned rats

Post-Training Memory Processing in Amygdala, Septum and Hippocampus: Role of Benzodiazepine/GABAA Receptors, and their Interaction with other Neurotransmitter Systems ⬇️

Pre-training to find a hidden platform in the Morris water maze can compensate for a deficit to find a cued platform in a rat model of Parkinson's disease

Putative role of monoamines in the antidepressant-like mechanism induced by striatal MT2 blockade

REM sleep deprivation generates cognitive and neurochemical disruptions in the intranigral rotenone model of Parkinson's disease

REM sleep deprivation reverses neurochemical and other depressive-like alterations induced by olfactory bulbectomy

Role of brainstem serotonin in analgesia produced by low-intensity exercise on neuropathic pain after sciatic nerve injury in mice

Roles of D1-like dopamine receptors in the nucleus accumbens and dorsolateral striatum in conditioned avoidance responses

Selegiline reverses aβ₂₅₋₃₅-induced cognitive deficit in male mice.

Special issue on the role of the basal ganglia in learning and memory. Preface

Spironolactone and low-dose dexamethasone enhance extinction of contextual fear conditioning.

Subchronic fluoride intake induces impairment in habituation and active avoidance tasks in rats.

The "anxiety state" and its relation with rat models of memory and habituation.

The COX-2 inhibitor parecoxib produces neuroprotective effects in MPTP-lesioned rats.

The brain decade in debate: III. Neurobiology of emotion.

The effect of caffeine in animal models of learning and memory

The lesion of the rat substantia nigra pars compacta dopaminergic neurons as a model for Parkinson's disease memory disabilities.

The mechanism of antidepressant-like effects of piroxicam in rats.

The nonsteroidal antiinflammatory drug piroxicam reverses the onset of depressive-like behavior in 6-OHDA animal model of Parkinson's disease.

The role of nucleus accumbens and dorsolateral striatal D2 receptors in active avoidance conditioning.

The role of the basal ganglia in motivated behavior

The role of the ventrolateral caudoputamen in predatory hunting.