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List of works by Roslyn M. Bill

A new panel of epitope mapped monoclonal antibodies recognising the prototypical tetraspanin CD81.

scientific article published on 7 September 2017

A regulatory domain in the C-terminal extension of the yeast glycerol channel Fps1p

scientific article published on 28 January 2004

A short regulatory domain restricts glycerol transport through yeast Fps1p.

scientific article

Altering the ribosomal subunit ratio in yeast maximizes recombinant protein yield

scientific article

An emerging consensus on aquaporin translocation as a regulatory mechanism ⬇️

scientific article published on November 21, 2012

Analysis of the pore of the unusual major intrinsic protein channel, yeast Fps1p.

scientific article published on 09 July 2001

Analyzing Recombinant Protein Production in Pichia pastoris with Targeted Proteomics

scientific article published on 01 January 2019

Anti-DNA autoantibodies: the other DNA-binding proteins.

scientific article published on March 1997

Antifoam addition to shake flask cultures of recombinant Pichia pastoris increases yield

scientific article published on 22 March 2011

Aquaporins and Their Regulation after Spinal Cord Injury

scientific article published on 18 October 2018

Attenuated total reflection-FT-IR spectroscopic imaging of protein crystallization

scientific article published in May 2009

Beyond water homeostasis: Diverse functional roles of mammalian aquaporins

scientific article published on 10 September 2015

Biomimetic water channels: general discussion

scientific article published on 01 September 2018

CD81 extracted in SMALP nanodiscs comprises two distinct protein populations within a lipid environment enriched with negatively charged headgroups

scientific article published on 28 July 2020

COS-1 cell expression and one-step affinity protein purification and activity of epitope-tagged human erythropoietin and of site-directed mutants

scientific article published on 01 June 1997

Carnosine: can understanding its actions on energy metabolism and protein homeostasis inform its therapeutic potential?

scientific article published on 25 February 2013

Characterization of a unique anti-DNA hybridoma

scientific article published in February 1998

Chemical and biological approaches to glycoprotein synthesis

scientific article published on 01 March 1996

Conditional osmotic stress in yeast: a system to study transport through aquaglyceroporins and osmostress signaling

scientific article published on 17 December 2004

Constitutively-stressed yeast strains are high-yielding for recombinant Fps1: implications for the translational regulation of an aquaporin.

scientific article published on 9 March 2017

Design of improved membrane protein production experiments: quantitation of the host response

scientific article published in July 2005

Developing a scalable model of recombinant protein yield from Pichia pastoris: the influence of culture conditions, biomass and induction regime.

scientific article published on July 2009

Development of recombinant, immobilised β-1,4-mannosyltransferase for use as an efficient tool in the chemoenzymatic synthesis of N-linked oligosaccharides

article

Downregulation of aquaporin 3 inhibits cellular proliferation, migration and invasion in the MDA-MB-231 breast cancer cell line.

scientific article published on 21 May 2018

Editorial overview: New protein production tools for structural biology

scientific article published on 21 May 2015

Engineering of a novel Saccharomyces cerevisiae wine strain with a respiratory phenotype at high external glucose concentrations.

scientific article published on October 2005

Equipping a Research Scale Fermentation Laboratory for Production of Membrane Proteins

article

Eukaryotic expression: developments for structural proteomics.

scientific article published on 19 September 2006

Exceptional overproduction of a functional human membrane protein

scientific article published on 10 August 2007

Expression and mutagenesis of recombinant human and murine erythropoietins in Escherichia coli

article

Expression and purification of recombinant G protein-coupled receptors: A review

scientific article published on 31 October 2019

Expression of heterologous aquaporins for functional analysis in Saccharomyces cerevisiae

scientific article published on 18 August 2006

Foreword for EDICT Special Edition, volume 2 ⬇️

scientific article published on January 23, 2013

Functional Expression of Multidrug Resistance Protein 4 MRP4/ABCC4

scientific article published on 05 August 2019

Functional recombinant protein is present in the pre-induction phases of Pichia pastoris cultures when grown in bioreactors, but not shake-flasks

scientific article published on 4 September 2014

Functional split and crosslinking of the membrane domain of the beta subunit of proton-translocating transhydrogenase from Escherichia coli

scientific article published in September 2003

G-protein coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent.

scientific article published on 16 April 2015

GPCR production in a novel yeast strain that makes cholesterol-like sterols

scientific article published on 06 October 2011

GPCR-styrene maleic acid lipid particles (GPCR-SMALPs): their nature and potential.

scientific article published on April 2016

High-yield overproduction and purification of human aquaporins from <i>Pichia pastoris</i>

scientific article published on 12 April 2022

Hijacked then lost in translation: the plight of the recombinant host cell in membrane protein structural biology projects

scientific article

Human aquaporins: regulators of transcellular water flow

scientific article published on 30 September 2013

Hypothermia increases aquaporin 4 (AQP4) plasma membrane abundance in human primary cortical astrocytes via a calcium/transient receptor potential vanilloid 4 (TRPV4)- and calmodulin-mediated mechanism

scientific article published on 19 September 2017

Identification and Molecular Mechanisms of the Rapid Tonicity-induced Relocalization of the Aquaporin 4 Channel.

scientific article published on 26 May 2015

Identification of residues controlling transport through the yeast aquaglyceroporin Fps1 using a genetic screen.

scientific article published in February 2004

Improving recombinant eukaryotic membrane protein yields in Pichia pastoris: the importance of codon optimization and clone selection

scientific article

Increasing cell biomass in Saccharomyces cerevisiae increases recombinant protein yield: the use of a respiratory strain as a microbial cell factory

scientific article published on 17 June 2010

Inhibitors of Mammalian Aquaporin Water Channels ⬇️

scientific article published on 29 March 2019

L-Carnosine Affects the Growth of Saccharomyces cerevisiae in a Metabolism-Dependent Manner ⬇️

scientific article published on September 12, 2012

Ligand-induced conformational changes in a SMALP-encapsulated GPCR

scientific article published on 29 February 2020

Lignocellulosic biorefineries: The current state of challenges and strategies for efficient commercialization

scientific article published in 2021

Mapping the yeast host cell response to recombinant membrane protein production: Relieving the biological bottlenecks ⬇️

scientific article published on March 24, 2011

Membrane Protein Production in the Yeast, S. cerevisiae.

scientific article published in January 2016

Membrane trafficking of aquaporin 1 is mediated by protein kinase C via microtubules and regulated by tonicity.

scientific article

Microbial MIP channels.

scientific article

Microbial drug efflux proteins of the major facilitator superfamily

scientific article published on July 2006

Microbial expression systems for membrane proteins ⬇️

scientific article published on 12 April 2018

Optimising yeast as a host for recombinant protein production (review).

scientific article published on January 2012

Overcoming barriers to membrane protein structure determination

scientific article

Overcoming bottlenecks in the membrane protein structural biology pipeline

scientific article published on June 2016

Pichia pastoris regulates its gene-specific response to different carbon sources at the transcriptional, rather than the translational, level.

scientific article published on 11 March 2015

Pichia pastoris versus Saccharomyces cerevisiae: a case study on the recombinant production of human granulocyte-macrophage colony-stimulating factor

scientific article

Plasma Membrane Abundance of Human Aquaporin 5 Is Dynamically Regulated by Multiple Pathways

scientific article published on 16 November 2015

Playing catch-up with Escherichia coli: using yeast to increase success rates in recombinant protein production experiments.

scientific article published on 5 March 2014

Production, purification and characterization of recombinant, full-length human claudin-1.

scientific article

Purification and immobilization of engineered glucose dehydrogenase: a new approach to producing gluconic acid from breadwaste

scientific article published on 03 June 2020

Rapid expression and purification of the hepatitis delta virus antigen using the methylotropic yeast Pichia pastoris

scientific article

Recombinant Membrane Protein Methods

scientific article published on 01 September 2018

Recombinant protein subunit vaccine synthesis in microbes: a role for yeast?

scientific article published on 31 December 2014

Relieving the first bottleneck in the drug discovery pipeline: using array technologies to rationalize membrane protein production.

scientific article published on October 2009

Role of hexose transport in control of glycolytic flux in Saccharomyces cerevisiae

scientific article

Roles of ABCC1 and ABCC4 in Proliferation and Migration of Breast Cancer Cell Lines

scientific article published on 16 October 2020

Selective in vitro glycosylation of recombinant proteins: semi-synthesis of novel homogeneous glycoforms of human erythropoietin

scientific article published in February 2001

Stabilization of Human Multidrug Resistance Protein 4 (MRP4/ABCC4) Using Novel Solubilization Agents

scientific article published on 05 August 2019

Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor

scientific article published on 14 May 2015

Structural Determinants of Oligomerization of the Aquaporin-4 Channel.

scientific article published on 19 January 2016

Structural characterization of CD81-Claudin-1 hepatitis C virus receptor complexes

scientific article published on April 2011

Structural characterization of recombinant human CD81 produced in Pichia pastoris

scientific article published on 24 October 2007

Structure and function of natural proteins for water transport: general discussion

scientific article published on 01 September 2018

Surfactant-free purification of membrane proteins with intact native membrane environment

scientific article published on June 2011

Switching the mode of metabolism in the yeast Saccharomyces cerevisiae

scientific article

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels

Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema

scientific article published on 01 May 2020

The effect of antifoam addition on protein production yields

scientific article published on 01 January 2012

The implementation of a design of experiments strategy to increase recombinant protein yields in yeast (review).

scientific article published on January 2012

The synthesis of recombinant membrane proteins in yeast for structural studies

scientific article

Transcriptome Analysis of Gene Expression Provides New Insights into the Effect of Mild Therapeutic Hypothermia on Primary Human Cortical Astrocytes Cultured under Hypoxia

scientific article published on 14 December 2017

Transcriptome analysis of a respiratory Saccharomyces cerevisiae strain suggests the expression of its phenotype is glucose insensitive and predominantly controlled by Hap4, Cat8 and Mig1

scientific article

Transcriptome analysis suggests a role for the differential expression of cerebral aquaporins and the MAPK signalling pathway in human temporal lobe epilepsy

scientific article published on 17 July 2017

Understanding the yeast host cell response to recombinant membrane protein production

scientific article published on 01 June 2011

Water channel pore size determines exclusion properties but not solute selectivity

scientific article published on 30 December 2019

Which Yeast Species Shall I Choose? Saccharomyces cerevisiae Versus Pichia pastoris (Review) ⬇️

scientific article published on January 1, 2012

Yeast--a panacea for the structure-function analysis of membrane proteins?

scientific article

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