List of works - Julie Dam

A Growing Family of Natural Killers

scientific article published on 01 June 2003

A role for the melatonin-related receptor GPR50 in leptin signaling, adaptive thermogenesis, and torpor.

scientific article published on 22 December 2011

Anti-obesity phenotypic screening looking to increase OBR cell surface expression

scientific article

Calculating sedimentation coefficient distributions by direct modeling of sedimentation velocity concentration profiles

scientific article

Complementation between dimeric mutants as a probe of dimer-dimer interactions in tetrameric dihydrofolate reductase encoded by R67 plasmid of E. coli.

scientific article published in September 2000

Do orphan G-protein-coupled receptors have ligand-independent functions? New insights from receptor heterodimers

scientific article

Effect of multiple symmetries on the association of R67 DHFR subunits bearing interfacial complementing mutations

scientific article published on January 2004

Endospanin 1 silencing in the hypothalamic arcuate nucleus contributes to sustained weight loss of high fat diet obese mice

scientific article published on May 2014

Endospanin1 affects oppositely body weight regulation and glucose homeostasis by differentially regulating central leptin signaling

scientific article

Endospanins regulate a postinternalization step of the leptin receptor endocytic pathway

scientific article

Histidine Decarboxylase Deficiency Prevents Autoimmune Diabetes in NOD Mice

scientific article published on 18 May 2015

Homozygous deletion of an 80kb region comprising part of DNAJC6 and LEPR genes on chromosome 1P31.3 is associated with early onset obesity, mental retardation and epilepsy ⬇️

scientific article published on May 10, 2012

Hunting for the functions of short leptin receptor isoforms.

scientific article published on 13 September 2013

Hypothalamic tanycytes are an ERK-gated conduit for leptin into the brain

scientific article published on February 2014

Leptin brain entry via a tanycytic LepR-EGFR shuttle controls lipid metabolism and pancreas function

scientific article published on 02 August 2021

L’endospanine 1 de l’hypothalamus dissocie l’obésité du diabète de type 2

scientific article published on 16 April 2018

Molecular Architecture of the Major Histocompatibility Complex Class I-binding Site of Ly49 Natural Killer Cell Receptors

scientific article

New pharmacological perspectives for the leptin receptor in the treatment of obesity

scientific article

Nocturnal activation of melatonin receptor type 1 signaling modulates diurnal insulin sensitivity via regulation of PI3K activity.

scientific article published on 16 December 2017

Quantitative assessment of oligomeric amyloid β peptide binding to α7 nicotinic receptor

scientific article published on 20 May 2019

Sedimentation equilibrium analysis of protein interactions with global implicit mass conservation constraints and systematic noise decomposition

scientific article published in March 2004

Sedimentation velocity analysis of heterogeneous protein-protein interactions: Lamm equation modeling and sedimentation coefficient distributions c(s)

scientific article

Sedimentation velocity analysis of heterogeneous protein-protein interactions: sedimentation coefficient distributions c(s) and asymptotic boundary profiles from Gilbert-Jenkins theory

scientific article

Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesity

scientific article

Techniques: new pharmacological perspectives for the leptin receptor

scientific article

The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization

scientific article

Variable Dimerization of the Ly49A Natural Killer Cell Receptor Results in Differential Engagement of its MHC Class I Ligand

scientific article published on 08 August 2006

Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b)

scientific article

List of works by Julie Dam

A Growing Family of Natural Killers

A role for the melatonin-related receptor GPR50 in leptin signaling, adaptive thermogenesis, and torpor.

Anti-obesity phenotypic screening looking to increase OBR cell surface expression

Calculating sedimentation coefficient distributions by direct modeling of sedimentation velocity concentration profiles

Complementation between dimeric mutants as a probe of dimer-dimer interactions in tetrameric dihydrofolate reductase encoded by R67 plasmid of E. coli.

Do orphan G-protein-coupled receptors have ligand-independent functions? New insights from receptor heterodimers

Effect of multiple symmetries on the association of R67 DHFR subunits bearing interfacial complementing mutations

Endospanin 1 silencing in the hypothalamic arcuate nucleus contributes to sustained weight loss of high fat diet obese mice

Endospanin1 affects oppositely body weight regulation and glucose homeostasis by differentially regulating central leptin signaling

Endospanins regulate a postinternalization step of the leptin receptor endocytic pathway

Histidine Decarboxylase Deficiency Prevents Autoimmune Diabetes in NOD Mice

Homozygous deletion of an 80kb region comprising part of DNAJC6 and LEPR genes on chromosome 1P31.3 is associated with early onset obesity, mental retardation and epilepsy ⬇️

Hunting for the functions of short leptin receptor isoforms.

Hypothalamic tanycytes are an ERK-gated conduit for leptin into the brain

Leptin brain entry via a tanycytic LepR-EGFR shuttle controls lipid metabolism and pancreas function

L’endospanine 1 de l’hypothalamus dissocie l’obésité du diabète de type 2

Molecular Architecture of the Major Histocompatibility Complex Class I-binding Site of Ly49 Natural Killer Cell Receptors

New pharmacological perspectives for the leptin receptor in the treatment of obesity

Nocturnal activation of melatonin receptor type 1 signaling modulates diurnal insulin sensitivity via regulation of PI3K activity.

Quantitative assessment of oligomeric amyloid β peptide binding to α7 nicotinic receptor

Sedimentation equilibrium analysis of protein interactions with global implicit mass conservation constraints and systematic noise decomposition

Sedimentation velocity analysis of heterogeneous protein-protein interactions: Lamm equation modeling and sedimentation coefficient distributions c(s)

Sedimentation velocity analysis of heterogeneous protein-protein interactions: sedimentation coefficient distributions c(s) and asymptotic boundary profiles from Gilbert-Jenkins theory

Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesity

Techniques: new pharmacological perspectives for the leptin receptor

The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization

Variable Dimerization of the Ly49A Natural Killer Cell Receptor Results in Differential Engagement of its MHC Class I Ligand

Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b)