List of works - Jochen Lang

A Central Small Amino Acid in the VAMP2 Transmembrane Domain Regulates the Fusion Pore in Exocytosis.

scientific article published on 6 June 2017

A charged prominence in the linker domain of the cysteine-string protein Cspα mediates its regulated interaction with the calcium sensor synaptotagmin 9 during exocytosis

scientific article

A game plan for exocytosis

scientific article published on 01 September 1994

A novel bioelectronic glucose sensor to process distinct electrical activities of pancreatic beta-cells.

scientific article

A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ

scientific article

A versatile electrode sorting module for MEAs: Implementation in a FPGA-based real-time system

Adenylyl cyclase 8 is central to glucagon-like peptide 1 signalling and effects of chronically elevated glucose in rat and human pancreatic beta cells

scientific journal article

Alpha-latrotoxin induces exocytosis by inhibition of voltage-dependent K+ channels and by stimulation of L-type Ca2+ channels via latrophilin in beta-cells

scientific article published on 21 November 2005

Bioelectronic organ-based sensor for microfluidic real-time analysis of the demand in insulin

scientific article published on 08 June 2018

Biosensors in diabetes : how to get the most out of evolution and transpose it into a signal

scientific article published on May 2014

Ca2+-independent insulin exocytosis induced by alpha-latrotoxin requires latrophilin, a G protein-coupled receptor

scientific article

Calcium influx activates adenylyl cyclase 8 for sustained insulin secretion in rat pancreatic beta cells.

scientific article published on 9 November 2014

Cell type-specific deletion in mice reveals roles for PAS kinase in insulin and glucagon production

scientific article published on 24 June 2016

Cysteine string protein interacts with and modulates the maturation of the cystic fibrosis transmembrane conductance regulator

scientific article

Cysteine-string protein isoform beta (Cspbeta) is targeted to the trans-Golgi network as a non-palmitoylated CSP in clonal beta-cells

scientific article published on 14 September 2006

Cysteine-string proteins regulate exocytosis of insulin independent from transmembrane ion fluxes

scientific article published on 01 October 1998

Design of Potassium-Selective Mixed Ion/Electron Conducting Polymers

scientific article published on 05 May 2020

Direct modulation of voltage-dependent calcium channels by muscarinic activation of a pertussis toxin-sensitive G-protein in hippocampal neurons

scientific article published on 01 December 1989

Distinct roles of the C2A and the C2B domain of the vesicular Ca2+ sensor synaptotagmin 9 in endocrine beta-cells

scientific article published on May 2007

Distribution of the alpha-subunit of the guanine nucleotide-binding protein Gi2 and its comparison to G alpha o

scientific article (publication date: 1989)

Effect of monolayer lipid charges on the structure and orientation of protein VAMP1 at the air–water interface

scientific article published on 18 January 2010

Exploring functional beta-cell heterogeneity in vivo using PSA-NCAM as a specific marker

scientific article published on 18 May 2009

Fusion pore in exocytosis: More than an exit gate? A β-cell perspective

scientific article published on 7 November 2017

G-protein betagamma-binding domains regulate insulin exocytosis in clonal pancreatic beta-cells

scientific article published on 01 March 1998

Glucotoxicity inhibits late steps of insulin exocytosis.

scientific article

Guiding pancreatic beta cells to target electrodes in a whole-cell biosensor for diabetes.

scientific article published on 18 August 2015

Loss-of-function mutations in ADCY3 cause monogenic severe obesity

scientific article published on 8 January 2018

Multilevel control of glucose homeostasis by adenylyl cyclase 8.

scientific article

Multimed: An Integrated, Multi-Application Platform for the Real-Time Recording and Sub-Millisecond Processing of Biosignals

scientific article published on 30 June 2018

Non-invasive long-term and real-time analysis of endocrine cells on micro-electrode arrays

scientific article published on 23 December 2011

Over-expression of Slc30a8/ZnT8 selectively in the mouse α cell impairs glucagon release and responses to hypoglycemia

scientific article published on 07 July 2016

PIPs and pools in insulin secretion

scientific article

Reversible transition between alpha-helix and beta-sheet conformation of a transmembrane domain

scientific article published on 29 May 2009

SNAP-25 is expressed in islets of Langerhans and is involved in insulin release.

scientific article

Simultaneous monitoring of single cell and of micro-organ activity by PEDOT:PSS covered multi-electrode arrays.

scientific article published on 19 July 2017

Slow potentials encode intercellular coupling and insulin demand in pancreatic beta cells

scientific article published on 19 March 2015

Soluble N-ethylmaleimide-sensitive-factor attachment protein and N-ethylmaleimide-insensitive factors are required for Ca2+-stimulated exocytosis of insulin.

scientific article published on February 1996

Splice variant 3, but not 2 of receptor protein-tyrosine phosphatase sigma can mediate stimulation of insulin-secretion by alpha-latrotoxin

scientific article

Synaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic β-cells

scientific journal article

Synaptotagmin 8 is expressed both as a calcium-insensitive soluble and membrane protein in neurons, neuroendocrine and endocrine cells

scientific journal article

Synthesis and characterization of anti-idiotypic anti-T4 antibodies

scientific article published on 01 January 1994

The calcium-sensing protein synaptotagmin 7 is expressed on different endosomal compartments in endocrine, neuroendocrine cells or neurons but not on large dense core vesicles

scientific article published on 03 February 2007

The first C2 domain of synaptotagmin is required for exocytosis of insulin from pancreatic beta-cells: action of synaptotagmin at low micromolar calcium.

scientific article

The glutamate receptor GluK2 contributes to the regulation of glucose homeostasis and its deterioration during aging

scientific article published on 01 October 2019

The transmembrane domain of the SNARE protein VAMP2 is highly sensitive to its lipid environment

scientific article published on 20 December 2018

The variable C-terminus of cysteine string proteins modulates exocytosis and protein-protein interactions

scientific article

List of works by Jochen Lang

A Central Small Amino Acid in the VAMP2 Transmembrane Domain Regulates the Fusion Pore in Exocytosis.

A charged prominence in the linker domain of the cysteine-string protein Cspα mediates its regulated interaction with the calcium sensor synaptotagmin 9 during exocytosis

A game plan for exocytosis

A novel bioelectronic glucose sensor to process distinct electrical activities of pancreatic beta-cells.

A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ

A versatile electrode sorting module for MEAs: Implementation in a FPGA-based real-time system

Adenylyl cyclase 8 is central to glucagon-like peptide 1 signalling and effects of chronically elevated glucose in rat and human pancreatic beta cells

Alpha-latrotoxin induces exocytosis by inhibition of voltage-dependent K+ channels and by stimulation of L-type Ca2+ channels via latrophilin in beta-cells

Bioelectronic organ-based sensor for microfluidic real-time analysis of the demand in insulin

Biosensors in diabetes : how to get the most out of evolution and transpose it into a signal

Ca2+-independent insulin exocytosis induced by alpha-latrotoxin requires latrophilin, a G protein-coupled receptor

Calcium influx activates adenylyl cyclase 8 for sustained insulin secretion in rat pancreatic beta cells.

Cell type-specific deletion in mice reveals roles for PAS kinase in insulin and glucagon production

Cysteine string protein interacts with and modulates the maturation of the cystic fibrosis transmembrane conductance regulator

Cysteine-string protein isoform beta (Cspbeta) is targeted to the trans-Golgi network as a non-palmitoylated CSP in clonal beta-cells

Cysteine-string proteins regulate exocytosis of insulin independent from transmembrane ion fluxes

Design of Potassium-Selective Mixed Ion/Electron Conducting Polymers

Direct modulation of voltage-dependent calcium channels by muscarinic activation of a pertussis toxin-sensitive G-protein in hippocampal neurons

Distinct roles of the C2A and the C2B domain of the vesicular Ca2+ sensor synaptotagmin 9 in endocrine beta-cells

Distribution of the alpha-subunit of the guanine nucleotide-binding protein Gi2 and its comparison to G alpha o

Effect of monolayer lipid charges on the structure and orientation of protein VAMP1 at the air–water interface

Exploring functional beta-cell heterogeneity in vivo using PSA-NCAM as a specific marker

Fusion pore in exocytosis: More than an exit gate? A β-cell perspective

G-protein betagamma-binding domains regulate insulin exocytosis in clonal pancreatic beta-cells

Glucotoxicity inhibits late steps of insulin exocytosis.

Guiding pancreatic beta cells to target electrodes in a whole-cell biosensor for diabetes.

Loss-of-function mutations in ADCY3 cause monogenic severe obesity

Multilevel control of glucose homeostasis by adenylyl cyclase 8.

Multimed: An Integrated, Multi-Application Platform for the Real-Time Recording and Sub-Millisecond Processing of Biosignals

Non-invasive long-term and real-time analysis of endocrine cells on micro-electrode arrays

Over-expression of Slc30a8/ZnT8 selectively in the mouse α cell impairs glucagon release and responses to hypoglycemia

PIPs and pools in insulin secretion

Reversible transition between alpha-helix and beta-sheet conformation of a transmembrane domain

SNAP-25 is expressed in islets of Langerhans and is involved in insulin release.

Simultaneous monitoring of single cell and of micro-organ activity by PEDOT:PSS covered multi-electrode arrays.

Slow potentials encode intercellular coupling and insulin demand in pancreatic beta cells

Soluble N-ethylmaleimide-sensitive-factor attachment protein and N-ethylmaleimide-insensitive factors are required for Ca2+-stimulated exocytosis of insulin.

Splice variant 3, but not 2 of receptor protein-tyrosine phosphatase sigma can mediate stimulation of insulin-secretion by alpha-latrotoxin

Synaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic β-cells

Synaptotagmin 8 is expressed both as a calcium-insensitive soluble and membrane protein in neurons, neuroendocrine and endocrine cells

Synthesis and characterization of anti-idiotypic anti-T4 antibodies

The calcium-sensing protein synaptotagmin 7 is expressed on different endosomal compartments in endocrine, neuroendocrine cells or neurons but not on large dense core vesicles

The first C2 domain of synaptotagmin is required for exocytosis of insulin from pancreatic beta-cells: action of synaptotagmin at low micromolar calcium.

The glutamate receptor GluK2 contributes to the regulation of glucose homeostasis and its deterioration during aging

The transmembrane domain of the SNARE protein VAMP2 is highly sensitive to its lipid environment

The variable C-terminus of cysteine string proteins modulates exocytosis and protein-protein interactions