List of works by James Campbell

A genetic screen using the PiggyBac transposon in haploid cells identifies Parp1 as a mediator of olaparib toxicity

scientific article

A novel strategy using MASCOT Distiller for analysis of cleavable isotope-coded affinity tag data to quantify protein changes in plasma

scientific article

ATR Is a Therapeutic Target in Synovial Sarcoma.

scientific article published on 16 October 2017

ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A.

scientific article published on 13 December 2016

Abstract 5076: Integrative genomic and transcriptomic analysis of metaplastic carcinomas of the breast

article by Alan G. Mackay et al published 15 April 2012 in Cancer Research

Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease

scientific article

Author Correction: Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness

scientific article published in Scientific Reports

CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours

scientific article

CancerGD: A Resource for Identifying and Interpreting Genetic Dependencies in Cancer

scientific article published on 11 July 2017

CancerGD: a resource for identifying and interpreting genetic dependencies in cancer

scholarly article published 26 October 2016

Candidate verification of iron-regulated Neisseria meningitidis proteins using isotopic versions of tandem mass tags (TMT) and single reaction monitoring

scientific article published on 22 September 2009

Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness

scientific article published on 13 July 2018

Comparison of a protein-level and peptide-level labeling strategy for quantitative proteomics of synaptosomes using isobaric tags

scientific article published in May 2010

Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours

scientific article published on 20 April 2017

Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours

scientific article published on 18 April 2016

Correction: Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours

scientific article published in PLoS ONE

Coupling bimolecular PARylation biosensors with genetic screens to identify PARylation targets.

scientific article

E-Cadherin/ROS1 Inhibitor Synthetic Lethality in Breast Cancer.

scientific article published in April 2018

Efficacy of chemotherapy in BRCA1/2 mutation carrier ovarian cancer in the setting of PARP inhibitor resistance: a multi-institutional study

scientific article published on 06 August 2013

Elevated APOBEC3B expression drives a kataegic-like mutation signature and replication stress-related therapeutic vulnerabilities in p53-defective cells

scientific article

Evaluation of CDK12 Protein Expression as a Potential Novel Biomarker for DNA Damage Response-Targeted Therapies in Breast Cancer.

scientific article published on 13 November 2017

Evaluation of absolute peptide quantitation strategies using selected reaction monitoring

scientific article published on 16 February 2011

Exome Sequencing of an Adult Pituitary Atypical Teratoid Rhabdoid Tumor

scientific article

Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance.

scientific article published on 10 May 2018

Genome-wide barcoded transposon screen for cancer drug sensitivity in haploid mouse embryonic stem cells

scientific article

Genome-wide characterization reveals complex interplay between TP53 and TP63 in response to genotoxic stress

scientific article published on 13 May 2014

Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity

scientific article

High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial

scientific article published on 13 May 2016

Identification of highly penetrant Rb-related synthetic lethal interactions in triple negative breast cancer

scientific article published on 18 June 2018

Identifying Genetic Dependencies in Cancer by Analyzing siRNA Screens in Tumor Cell Line Panels

scientific article published in January 2018

Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines

scientific article published on 2 March 2016

Mapping genetic vulnerabilities reveals BTK as a novel therapeutic target in oesophageal cancer

scientific article

Modeling Therapy Resistance in BRCA1/2-Mutant Cancers.

scientific article published on 15 June 2017

Optimised ARID1A immunohistochemistry is an accurate predictor of ARID1A mutational status in gynaecological cancers.

scientific article published on 16 April 2018

Parallel RNA interference screens identify EGFR activation as an escape mechanism in FGFR3-mutant cancer ⬇️

scientific article published on 6 June 2013

Pharmacoproteomic investigation into antidepressant response in two mouse inbred strains

scientific article

Plasma biomarkers of brain atrophy in Alzheimer's disease

scientific article (publication date: 2011)

Plasma gelsolin is decreased and correlates with rate of decline in Alzheimer's disease

scientific article

Poly (ADP-ribose) polymerase (PARP) inhibitors for the treatment of advanced germline BRCA2 mutant prostate cancer

scientific article published on 22 March 2013

Proteome-based plasma markers of brain amyloid-β deposition in non-demented older individuals

scientific article

Proteomics for brain disorders--the promise for biomarkers

scientific article published on October 2009

Secondary mutations inBRCA2associated with clinical resistance to a PARP inhibitor

article by Louise J Barber et al published 25 January 2013 in Journal of Pathology

Synthetic Lethal Targeting of ARID1A-Mutant Ovarian Clear Cell Tumors with Dasatinib

scientific article

The genomic landscape of oesophagogastric junctional adenocarcinoma

scientific article

Therapeutic vulnerabilities in the DNA damage response for the treatment of ATRX mutant neuroblastoma

scientific article published on 23 August 2020

Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model

scientific article published on 11 August 2016

Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C.

scientific article

Whole-exome DNA sequence analysis of Brca2- and Trp53-deficient mouse mammary gland tumours

scientific article published on 2 April 2015

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