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List of works by Maria Serrano

A homozygous nonsense mutation (c.214C->A) in the biliverdin reductase alpha gene (BLVRA) results in accumulation of biliverdin during episodes of cholestasis.

scientific article published on 28 January 2011

A review on the molecular mechanisms involved in the placental barrier for drugs.

scientific article

Antiviral effect of artemisinin from Artemisia annua against a model member of the Flaviviridae family, the bovine viral diarrhoea virus (BVDV).

scientific article published on 10 August 2006

Beneficial effect of ursodeoxycholic acid on alterations induced by cholestasis of pregnancy in bile acid transport across the human placenta.

scientific article

Carriers involved in targeting the cytostatic bile acid-cisplatin derivatives cis-diammine-chloro-cholylglycinate-platinum(II) and cis-diammine-bisursodeoxycholate-platinum(II) toward liver cells.

scientific article published in April 2002

Characterization of WIF-B9/R cells as an in vitro model with hepatocyte-like polarity and enhanced expression of canalicular ABC transporters involved in phase III of hepatic detoxification.

scientific article published on 9 January 2007

Chemoresistance and chemosensitization in cholangiocarcinoma.

scientific article

Cholephilic characteristics of a new cytostatic complex of cisplatin with glycocholate (Bamet-R2)

scientific article published on 01 February 1999

Cisplatin-induced chemoresistance in colon cancer cells involves FXR-dependent and FXR-independent up-regulation of ABC proteins.

scientific article

Comparison of the effects of bile acids on cell viability and DNA synthesis by rat hepatocytes in primary culture

article

DNA interaction and cytostatic activity of the new liver organotropic complex of cisplatin with glycocholic acid: Bamet-R2.

scientific article

Different Temperature Sensitivity and Cation Specificity of Two Distinct d-Glucose/Na+Cotransport Systems in the Intestinal Brush-Border Membrane

scientific article published on 01 January 1985

Effect of artemisinin/artesunate as inhibitors of hepatitis B virus production in an "in vitro" replicative system.

scientific article published on 10 August 2005

Effect of cantharidin, cephalotaxine and homoharringtonine on "in vitro" models of hepatitis B virus (HBV) and bovine viral diarrhoea virus (BVDV) replication

scientific article published on 26 April 2007

Effect of maternal cholestasis and treatment with ursodeoxycholic acid on the expression of genes involved in the secretion of biliary lipids by the neonatal rat liver.

scientific article

Effect of ursodeoxycholic acid on the impairment induced by maternal cholestasis in the rat placenta-maternal liver tandem excretory pathway

scientific article published on 24 January 2003

Evidence for carrier-mediated transport of unconjugated bilirubin across plasma membrane vesicles from human placental trophoblast.

scientific article

Evidence for dual effect of bile acids on thymidine anabolism and catabolism by the regenerating rat liver.

scientific article published in February 1996

Evidence for dual effects of DNA-reactive bile acid derivatives (Bamets) on hepatitis B virus life cycle in an in vitro replicative system.

scientific article published in November 2002

Evidence for the presence of carbonic anhydrase in the plasma membrane of rat hepatocytes

scientific article published in November 1988

Excretion of biliary compounds during intrauterine life.

scientific article published on February 2009

Excretion of fetal biliverdin by the rat placenta-maternal liver tandem.

scientific article published on 3 November 2005

Excretion of foetal bilirubin by the rat placenta-maternal liver tandem.

scientific article published in May 2003

Expression in human trophoblast and choriocarcinoma cell lines, BeWo, Jeg-3 and JAr of genes involved in the hepatobiliary-like excretory function of the placenta.

scientific article published on 19 May 2006

In vitro test to determine the effect of cytostatic drugs on co-cultured rat hepatocytes and hepatoma cells

scientific article published on 01 April 1998

Influence of hydroxylation and conjugation in cross-inhibition of bile acid transport across the human trophoblast basal membrane.

scientific article

Long-term effect of treating pregnant rats with ursodeoxycholic acid on the congenital impairment of bile secretion induced in the pups by maternal cholestasis

scientific article

Molecular bases of the fetal liver-placenta-maternal liver excretory pathway for cholephilic compounds.

scientific article published on April 2008

No correlation between the expression of FXR and genes involved in multidrug resistance phenotype of primary liver tumors.

scientific article

Novel artemisinin derivatives with potential usefulness against liver/colon cancer and viral hepatitis.

scientific article published on 29 April 2013

Novel bile acid derivatives (BANBs) with cytostatic activity obtained by conjugation of their side chain with nitrogenated bases

scientific article published on 28 December 2006

Novel cationic and neutral glycocholic acid and polyamine conjugates able to inhibit transporters involved in hepatic and intestinal bile acid uptake.

scientific article published on 19 January 2007

Physiological characteristics of allo-cholic acid

scientific article

Potential role of trans-inhibition of the bile salt export pump by progesterone metabolites in the etiopathogenesis of intrahepatic cholestasis of pregnancy

scientific article published on 7 November 2005

Predominance of human versus rat phenotype in the metabolic pathways for bile acid synthesis by hybrid WIF-B9 cells ⬇️

scientific article published on November 30, 2001

Protective role of biliverdin against bile acid-induced oxidative stress in liver cells.

scientific article

Relationship between asymptomatic hypercholanaemia of pregnancy and progesterone metabolism

scientific article published in May 2002

Relationship between tumor cell load and sensitivity to the cytostatic effect of two novel platinum-bile acid complexes, Bamet-D3 and Bamet-UD2.

scientific article published in August 2002

Role of Genetic Variations in the Hepatic Handling of Drugs

scientific article published on 20 April 2020

Role of organic anion-transporting polypeptides, OATP-A, OATP-C and OATP-8, in the human placenta-maternal liver tandem excretory pathway for foetal bilirubin.

scientific article published in May 2003

Role of rate-limiting enzymes of nucleotide metabolism in taurocholate-induced DNA synthesis inhibition

scientific article published on 01 August 1996

Role of vitamin C transporters and biliverdin reductase in the dual pro-oxidant and anti-oxidant effect of biliary compounds on the placental-fetal unit in cholestasis during pregnancy

scientific article

Sensitivity of bile acid transport by organic anion-transporting polypeptides to intracellular pH.

scientific article published in April 2003

Serum glycosidases in diabetes mellitus in relation to the retinopathy and to the length of the disease

scientific article published on 01 July 1983

Synthesis and Characterization of the New Cytostatic Complexcis-Diammineplatinum(II)−Chlorocholylglycinate

scientific article published on 01 July 1997

Temporal expression profiles of organic anion transport proteins in placenta and fetal liver of the rat

scientific journal article

The hepatobiliary-like excretory function of the placenta. A review.

scientific article

The role of reduced intracellular concentrations of active drugs in the lack of response to anticancer chemotherapy

scientific article

Up-regulation of FXR isoforms is not required for stimulation of the expression of genes involved in the lack of response of colon cancer to chemotherapy.

scientific article published on 8 August 2012

Usefulness of liposomes loaded with cytostatic bile acid derivatives to circumvent chemotherapy resistance of enterohepatic tumors.

scientific article published in March 2003

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