Search filters

Authors whose works are in public domain in at least one jurisdiction

List of works by Maria Grazia De Simoni

2-Aminotetraline derivative protects from ischemia/reperfusion brain injury with a broad therapeutic window

scientific article published on 22 November 2006

A New Surface Plasmon Resonance Assay for In Vitro Screening of Mannose-Binding Lectin Inhibitors.

scientific article published on 11 March 2016

A close look at brain dynamics: cells and vessels seen by in vivo two-photon microscopy

scientific article published on 08 July 2014

Activation of the hypothalamic serotoninergic system by central interleukin-1.

scientific article published in December 1991

Acute hypertension induces oxidative stress in brain tissues

scientific article published in February 2006

Aging prolongs the stress-induced release of noradrenaline in rat hypothalamus

scientific article published in July 1993

Alzheimer's disease: another target for heparin therapy.

scientific article

Arterially perfused neurosphere-derived cells distribute outside the ischemic core in a model of transient focal ischemia and reperfusion in vitro

scientific article

Aspartame and the rat brain monoaminergic system.

scientific article published in December 1988

Basal and stress-induced release of noradrenaline in hypothalamus of spontaneously hypertensive rats at different ages.

scientific article published on December 1994

Bone marrow mesenchymal stromal cells drive protective M2 microglia polarization after brain trauma

scientific article

C1-inhibitor attenuates neurobehavioral deficits and reduces contusion volume after controlled cortical impact brain injury in mice

scientific article published in February 2009

C1-inhibitor protects against brain ischemia-reperfusion injury via inhibition of cell recruitment and inflammation

scientific article published in June 2005

CX3CL1 is neuroprotective in permanent focal cerebral ischemia in rodents

scientific article published in November 2011

CX3CR1 deficiency induces an early protective inflammatory environment in ischemic mice.

scientific article published on 26 February 2013

Cerebrospinal fluid pentraxin 3 early after subarachnoid hemorrhage is associated with vasospasm

scientific article

Changes in the serotonergic system during the sleep-wake cycle: simultaneous polygraphic and voltammetric recordings in hypothalamus using a telemetry system.

scientific article published in January 1994

Cholinergic control of catechol metabolism in the rat locus coeruleus as studied by in vivo voltammetry

scientific article published in November 1983

Combined Genetic Deletion of IL (Interleukin)-4, IL-5, IL-9, and IL-13 Does Not Affect Ischemic Brain Injury in Mice

scientific article published on 05 July 2019

Critical Role and Therapeutic Control of the Lectin Pathway of Complement Activation in an Abortion-Prone Mouse Mating

scientific article published on 11 November 2015

Cytokine-Neurotransmitter Interactions in the Brain ⬇️

scientific article published on January 1, 1998

Cytokines and innate inflammation in the pathogenesis of human traumatic brain injury.

scientific article published on 16 September 2011

Dexamethasone Conjugation to Biodegradable Avidin-Nucleic-Acid-Nano-Assemblies Promotes Selective Liver Targeting and Improves Therapeutic Efficacy in an Autoimmune Hepatitis Murine Model

scientific article published on 18 March 2019

Differences in the effect of the antidepressant amineptine on striatal and limbic DOPAC measured by HPLC-ECD and in vivo voltammetry

scientific article published in April 1986

Different effects of fenfluramine isomers and metabolites on extracellular 5-HIAA in nucleus accumbens and hippocampus of freely moving rats

scientific article published on 01 August 1988

Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein-specific antibodies

scientific article published on 29 July 2016

Direct reprogramming of human bone marrow stromal cells into functional renal cells using cell-free extracts

scientific article

Early ficolin-1 is a sensitive prognostic marker for functional outcome in ischemic stroke

scientific article

Effect of traumatic brain injury on cognitive function in mice lacking p55 and p75 tumor necrosis factor receptors.

scientific article published in January 2008

Evidence for a different sensitivity to various central effects of interleukin-1 beta in mice

scientific article published in February 1992

Ficolin-3-mediated lectin complement pathway activation in patients with subarachnoid hemorrhage

scientific article published on 11 December 2013

Fractalkine Receptor Deficiency Is Associated with Early Protection but Late Worsening of Outcome following Brain Trauma in Mice

scientific article published on 16 July 2015

Functional and histological consequences of quinolinic and kainic acid-induced seizures on hippocampal somatostatin neurons

scientific article published in January 1991

Functional meaning of tryptophan-induced increase of 5-HT metabolism as clarified by in vivo voltammetry

scientific article published on 01 May 1987

Functional role of inflammatory cytokines and antiinflammatory molecules in seizures and epileptogenesis

scientific article

Glia activation and cytokine increase in rat hippocampus by kainic acid-induced status epilepticus during postnatal development

scientific article published in December 2003

Glial cells drive preconditioning-induced blood-brain barrier protection.

scientific article published on 7 April 2011

Glutamate release in the nucleus tractus solitarius induced by peripheral lipopolysaccharide and interleukin-1 beta.

scientific article published on October 1998

Glycogen synthase kinase-3 inhibition reduces ischemic cerebral damage, restores impaired mitochondrial biogenesis and prevents ROS production

scientific article

HSV-1-mediated IL-1 receptor antagonist gene therapy ameliorates MOG(35-55)-induced experimental autoimmune encephalomyelitis in C57BL/6 mice.

scientific article

Heart-fatty acid-binding and tau proteins relate to brain injury severity and long-term outcome in subarachnoid haemorrhage patients

scientific article published on 5 May 2013

Heparin attenuates cytotoxic and inflammatory activity of Alzheimer amyloid-beta in vitro

scientific article

Human brain trauma severity is associated with lectin complement pathway activation

scientific article published in January 2018

Human umbilical cord blood mesenchymal stem cells protect mice brain after trauma.

scientific article

Hypothalamic serotonergic activity correlates better with brain temperature than with sleep-wake cycle and muscle tone in rats

scientific article

Imaging T-cell movement in the brain during experimental cerebral malaria.

scientific article

Immunosuppression does not affect human bone marrow mesenchymal stromal cell efficacy after transplantation in traumatized mice brain

scientific article

Impaired central stress-induced release of noradrenaline in rats with heart failure: a microdialysis study

scientific article published in January 2002

In vivo studies on the enhancement of serotonin reuptake by tianeptine

scientific article published in March 1992

Induction of a transmissible tau pathology by traumatic brain injury

scientific article published on 01 September 2018

Inflammatory cytokines and related genes are induced in the rat hippocampus by limbic status epilepticus

article

Inflammatory response and glia activation in developing rat hippocampus after status epilepticus

scientific article published in January 2005

Interaction between serotonergic and dopaminergic systems detected in striatum by differential pulse voltammetry

scientific article published in April 1985

Interleukin-6, tumor necrosis factor and corticosterone induction by central lipopolysaccharide in aged rats

scientific article published on 01 January 1997

Internalization of nanopolymeric tracers does not alter characteristics of placental cells.

scientific article published on 14 March 2016

Intracerebroventricular injection of interleukin 1 induces high circulating levels of interleukin 6.

scientific article published on May 1990

Intracerebroventricular injection of the terminal complement complex causes inflammatory reaction in the rat brain

scientific article published in May 2003

Intravenous infusion of human bone marrow mesenchymal stromal cells promotes functional recovery and neuroplasticity after ischemic stroke in mice

scientific article

Lack of glucocorticoids sustains the stress-induced release of noradrenaline in the anterior hypothalamus.

scientific article

Lectin Complement Pathway and Its Bloody Interactions in Brain Ischemia

scientific article published on 3 November 2016

Lectin Pathway of Complement Activation Is Associated with Vulnerability of Atherosclerotic Plaques

scientific article published on 16 March 2017

Leptin is induced in the ischemic cerebral cortex and exerts neuroprotection through NF-kappaB/c-Rel-dependent transcription.

scientific article

Leukocyte recruitment in the cerebrospinal fluid of mice with experimental meningitis is inhibited by an antibody to junctional adhesion molecule (JAM).

scientific article

Long-lasting protection in brain trauma by endotoxin preconditioning

scientific article

Macrophages are essential for maintaining a M2 protective response early after ischemic brain injury

scientific article

Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1

scientific article published on 30 August 2016

Mannose-Binding Lectin Drives Platelet Inflammatory Phenotype and Vascular Damage After Cerebral Ischemia in Mice via IL (Interleukin)-1α

scientific article

Mannose-binding lectin has a direct deleterious effect on ischemic brain microvascular endothelial cells

scientific article published on 07 September 2019

Mannose-binding lectin is expressed after clinical and experimental traumatic brain injury and its deletion is protective

scientific article published in August 2014

Miniaturized optoelectronic system for telemetry of in vivo voltammetric signals

scientific article published in August 1990

Multiple and complex effects of buspirone on central dopaminergic system

scientific article published in April 1988

Nerve growth factor and transforming growth factor-beta serum levels in acute stroke patients. Possible involvement of neurotrophins in cerebrovascular disease

scientific article

Neuroprotective effect of C1-inhibitor following traumatic brain injury in mice.

scientific article published in January 2008

Neurosphere-derived cells exert a neuroprotective action by changing the ischemic microenvironment.

scientific article published on 18 April 2007

Peripheral Inflammatory Response in Alzheimer's Disease and Multiinfarct Dementia

scientific article published on 01 November 2002

Peripheral interleukin-6 administration increases extracellular concentrations of serotonin and the evoked release of serotonin in the rat striatum

scientific article

Peripheral treatment with enoxaparin, a low molecular weight heparin, reduces plaques and beta-amyloid accumulation in a mouse model of Alzheimer's disease.

scientific article published in April 2004

Permissive role of glucocorticoids on interleukin-1 activation of the hypothalamic serotonergic system

scientific article published in July 1994

Pharmacological inhibition of mannose-binding lectin ameliorates neurobehavioral dysfunction following experimental traumatic brain injury.

scientific article published on 10 May 2016

Prophylactic but not delayed administration of simvastatin protects against long-lasting cognitive and morphological consequences of neonatal hypoxic-ischemic brain injury, reduces interleukin-1beta and tumor necrosis factor-alpha mRNA induction, an

scientific article

Protection of Brain Injury by Amniotic Mesenchymal Stromal Cell-Secreted Metabolites.

scientific article published on 20 July 2016

Proteomic analysis of mouse brain cortex identifies metabolic down-regulation as a general feature of ischemic pre-conditioning

scientific article published on 3 August 2012

Reciprocal control of inflammatory cytokines, IL-1 and IL-6, and β-amyloid production in cultures

article

Recombinant C1 inhibitor in brain ischemic injury.

scientific article published in September 2009

Response by Perego et al to Letter Regarding Article, "Combined Genetic Deletion of IL (Interleukin)-4, IL-5, IL-9, and IL-13 Does Not Affect Ischemic Brain Injury in Mice"

scientific article published on 27 September 2019

Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia.

scientific article published on August 2015

SELENON (SEPN1) protects skeletal muscle from saturated fatty acid-induced ER stress and insulin resistance

scientific article published on 23 March 2019

Scaffold Optimisation of Tetravalent Antagonists of the Mannose Binding Lectin.

scientific article published on 23 December 2015

Selective inhibition of plasma kallikrein protects brain from reperfusion injury

scientific article published on 16 May 2006

Serotonin uptake inhibition: in vivo effect of sertraline in rats

scientific article published in May 1992

Similarities and differences between D-ALA2 MET5 enkephalin amide and morphine in the induction of tolerance to their effects on catalepsy and on dopamine metabolism in the rat brain.

scientific article published on November 1982

Simvastatin reduces caspase-3 activation and inflammatory markers induced by hypoxia-ischemia in the newborn rat.

scientific article published on 27 July 2005

Single severe traumatic brain injury produces progressive pathology with ongoing contralateral white matter damage one year after injury.

scientific article published on 7 November 2017

Six-month ischemic mice show sensorimotor and cognitive deficits associated with brain atrophy and axonal disorganization

scientific article published on 7 June 2013

Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury

scientific article published on 09 April 2019

THE EFFECT OF ETHER LIPID 1-O-OCTADECYL-2-O-METHOXY-RAC-GLYCERO-3-PHOSPHOCHOLINE AND ITS ANALOGUES PLATELET ACTIVATING FACTOR AND CARBAMYL-PLATELET ACTIVATING FACTOR ON THE BIOSYNTHESIS OF INTERLEUKIN-6 IN HUMAN THYMIC EPITHELIAL CELLS CULTIVATED IN

scientific article published on 01 September 1996

Targeted deletions of complement lectin pathway genes improve outcome in traumatic brain injury, with MASP-2 playing a major role

scientific article published on 28 October 2020

Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis.

scientific article published on 23 December 2016

Targeting mannose-binding lectin confers long-lasting protection with a surprisingly wide therapeutic window in cerebral ischemia.

scientific article

Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice ⬇️

scientific article published on December 10, 2011

The effect of opiate treatment on the postdecapitation reflex and monoamine metabolism in the rat spinal cord

scientific article published in September 1983

The genetics of small-vessel disease.

scientific article published on January 2012

The inflammatory response in cerebral ischemia: focus on cytokines in stroke patients

scientific article

The ischemic environment drives microglia and macrophage function

scientific article

The phagocytic state of brain myeloid cells after ischemia revealed by superresolution structured illumination microscopy

scientific article published on 16 January 2019

The sympathetic nervous system tonically inhibits peripheral interleukin-1beta and interleukin-6 induction by central lipopolysaccharide.

scientific article published on April 1998

Three-dimensional confocal analysis of microglia/macrophage markers of polarization in experimental brain injury

scientific article published on 4 September 2013

Tumor necrosis factor-alpha inhibits seizures in mice via p75 receptors

scientific article published in June 2005

Versatility of the complement system in neuroinflammation, neurodegeneration and brain homeostasis

scientific article

and evidence of dopaminergic system down regulation induced by chronic L-DOPA ⬇️

scientific article published on May 28, 1984

c-Jun N-terminal kinase pathway activation in human and experimental cerebral contusion.

scientific article published in September 2009

β-AMYLOID FRAGMENT POTENTIATES IL-6 AND TNF-α SECRETION BY LPS IN ASTROCYTES BUT NOT IN MICROGLIA

scientific article published on 01 October 1997

Paulina is supported by:

About Paulina

Help