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List of works by Alex Minella

Alternatively spliced, truncated GCSF receptor promotes leukemogenic properties and sensitivity to JAK inhibition

scientific article published on 30 October 2013

An integrated view of cyclin E function and regulation

scientific article published on January 2012

Anti-B-Cell Maturation Antigen BiTE Molecule AMG 420 Induces Responses in Multiple Myeloma

scientific article published on 02 January 2020

Cancer-associated SF3B1 mutants recognize otherwise inaccessible cryptic 3' splice sites within RNA secondary structures

scientific article published on 15 August 2016

Cellular stress pathways in pediatric bone marrow failure syndromes: many roads lead to neutropenia

scientific article

Chromosome instability underlies hematopoietic stem cell dysfunction and lymphoid neoplasia associated with impaired Fbw7-mediated cyclin E regulation

scientific article

Complex hypereosinophilia arising from post-polycythemia vera myelofibrosis: A case of imatinib-responsiveness.

scientific article

Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo.

scientific article published on June 2008

Cyclin-dependent kinase 1 (CDK1) and CDK2 have opposing roles in regulating interactions of splicing factor 3B1 with chromatin.

scientific article

Degenerate minigene library analysis enables identification of altered branch point utilization by mutant splicing factor 3B1 (SF3B1)

scientific article published on 01 January 2019

Developing a systems-based understanding of hematopoietic stem cell cycle control.

scientific article

E2F-2 Promotes Nuclear Condensation and Enucleation of Terminally Differentiated Erythroblasts

scientific article published on 17 October 2016

Fbw7-dependent cyclin E regulation ensures terminal maturation of bone marrow erythroid cells by restraining oxidative metabolism.

scientific article published on 22 July 2013

Human T-cell leukemia virus type 2 tax mutants that selectively abrogate NFkappaB or CREB/ATF activation fail to transform primary human T cells

scientific article

Hypoxia-inducible factor 1 is activated by dysregulated cyclin E during mammary epithelial morphogenesis

scientific article

MicroRNA-223 regulates cyclin E activity by modulating expression of F-box and WD-40 domain protein 7

scientific article

Outside the coding genome, mammalian microRNAs confer structural and functional complexity

scientific article

Ras activity regulates cyclin E degradation by the Fbw7 pathway.

scientific article

The Development and Use of Scalable Systems for Studying Aberrant Splicing in SF3B1-Mutant CLL

scientific article published on 01 January 2019

The Human 343delT HSPB5 Chaperone Associated with Early-onset Skeletal Myopathy Causes Defects in Protein Solubility

scientific article published on 19 May 2016

Transcriptional regulation of p21/CIP1 cell cycle inhibitor by PDEF controls cell proliferation and mammary tumor progression

scientific article

p53 and SCFFbw7 cooperatively restrain cyclin E-associated genome instability.

scientific article

p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation

scientific article published in October 2002

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