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List of works by Alexandra Paulo

1H NMR spectroscopic identification of protonable sites in cryptolepines with C-11 substituents containing two amino functionalities

scientific article published on 26 February 2012

2-(4'-aminobenzenamine)-pyrimidine, a new alpha-antagonist from Autonoë madeirensis

scientific article

A new Delta7,22 sterol from the bulbs of Autonoë madeirensis

scientific article published on 19 October 2005

Antiplasmodial activity of Cryptolepis sanguinolenta alkaloids from leaves and roots.

scientific article published on February 2000

Antitrypanosomal and cysteine protease inhibitory activities of alkyldiamine cryptolepine derivatives

scientific article published on 15 August 2012

Bis-alkylamine Indolo[3,2-b]quinolines as hemozoin ligands: implications for antimalarial cytostatic and cytocidal activities

scientific article published on 15 April 2014

Bis-alkylamine quindolone derivatives as new antimalarial leads

scientific article published on 12 August 2010

C-11 diamino cryptolepine derivatives NSC748392, NSC748393, and NSC748394: anticancer profile and G-quadruplex stabilization

scientific article published on 29 September 2010

Chemotaxonomic analysis of the genus Cryptolepis

scientific article published in 2003

Combining 1,3-Ditriazolylbenzene and Quinoline to Discover a New G-Quadruplex-Interactive Small Molecule Active against Cancer Stem-Like Cells

scientific article published on 14 June 2019

Comparative in vitro and in vivo antimalarial activity of the indole alkaloids ellipticine, olivacine, cryptolepine and a synthetic cryptolepine analog.

scientific article published on 23 October 2012

Cryptolepine analogues containing basic aminoalkyl side-chains at C-11: synthesis, antiplasmodial activity, and cytotoxicity

scientific article published on 9 January 2008

Cryptolepine and quindoline: understanding their photophysics

scientific article published on 7 March 2017

Cryptolepis sanguinolenta activity against diarrhoeal bacteria.

scientific article published in October 1994

Cytoprotective effect of Coreopsis tinctoria extracts and flavonoids on tBHP and cytokine-induced cell injury in pancreatic MIN6 cells

scientific article

Design of Modular G-quadruplex Ligands.

scientific article published on 7 March 2018

Effects of some natural 5-hydroxy-isoflavones on cultured human endothelial cells in presence and absence of hydrogen peroxide

scientific article published in January 2006

Exploring the 3-piperidin-4-yl-1H-indole scaffold as a novel antimalarial chemotype

scientific article published on 31 July 2015

Flavonoids of an extract of Pterospartum tridentatum showing endothelial protection against oxidative injury

scientific article published in August 2004

In vitro antibacterial screening of Cryptolepis sanguinolenta alkaloids

scientific article

Incorporation of basic side chains into cryptolepine scaffold: structure-antimalarial activity relationships and mechanistic studies

scientific article published on 5 January 2011

Indolo[3,2-c]quinoline G-quadruplex stabilizers: a structural analysis of binding to the human telomeric G-quadruplex

scientific article published on 26 March 2015

Indoloquinolines as scaffolds for drug discovery.

scientific article published on January 2010

KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines.

scientific article published on 8 April 2015

N10,N11-di-alkylamine indolo[3,2-b]quinolines as hemozoin inhibitors: design, synthesis and antiplasmodial activity

scientific article published on 13 February 2015

New Alkaloids from Cryptolepis sanguinolenta

Oncogene Expression Modulation in Cancer Cell Lines by DNA G-Quadruplex-Interactive Small Molecules

scientific article

Recovery of oral glucose tolerance by Wistar rats after treatment with Coreopsis tinctoria infusion

scientific article published on May 2010

Small molecule inhibitors of multidrug resistance gene (MDR1) expression: preclinical evaluation and mechanisms of action

scientific article

Steroidal alkaloids from Cryptolepis obtusa

scientific article published on 01 February 2000

Structural elucidation of natural 2-hydroxy di- and tricarboxylic acids and esters, phenylpropanoid esters and a flavonoid from Autonoë madeirensis using gas chromatographic/electron ionization, electrospray ionization and tandem mass spectrometric

scientific article published on 01 December 2003

Synthesis, G-quadruplex stabilisation, docking studies, and effect on cancer cells of indolo[3,2-b]quinolines with one, two, or three basic side chains.

scientific article published on 19 August 2013

Targeting KRAS Oncogene in Colon Cancer Cells with 7-Carboxylate Indolo[3,2-b]quinoline Tri-Alkylamine Derivatives.

scientific article published on 29 May 2015

The flavonoid-rich fraction of Coreopsis tinctoria promotes glucose tolerance regain through pancreatic function recovery in streptozotocin-induced glucose-intolerant rats

scientific article published on 9 September 2010

The opposing effects of the flavonoids isoquercitrin and sissotrin, isolated from Pterospartum tridentatum, on oral glucose tolerance in rats

scientific article

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