List of works - João Lavrado

1H NMR spectroscopic identification of protonable sites in cryptolepines with C-11 substituents containing two amino functionalities

scientific article published on 26 February 2012

Antitrypanosomal and cysteine protease inhibitory activities of alkyldiamine cryptolepine derivatives

scientific article published on 15 August 2012

Bis-alkylamine Indolo[3,2-b]quinolines as hemozoin ligands: implications for antimalarial cytostatic and cytocidal activities

scientific article published on 15 April 2014

Bis-alkylamine quindolone derivatives as new antimalarial leads

scientific article published on 12 August 2010

C-11 diamino cryptolepine derivatives NSC748392, NSC748393, and NSC748394: anticancer profile and G-quadruplex stabilization

scientific article published on 29 September 2010

Comparative in vitro and in vivo antimalarial activity of the indole alkaloids ellipticine, olivacine, cryptolepine and a synthetic cryptolepine analog.

scientific article published on 23 October 2012

Cryptolepine analogues containing basic aminoalkyl side-chains at C-11: synthesis, antiplasmodial activity, and cytotoxicity

scientific article published on 9 January 2008

Cryptolepine and quindoline: understanding their photophysics

scientific article published on 7 March 2017

Estimation of the anthropogenic fraction of elements in surface sediments of the Tagus Estuary (Portugal).

scientific article published on 22 May 2008

Evaluation of Acridine Orange Derivatives as DNA-Targeted Radiopharmaceuticals for Auger Therapy: Influence of the Radionuclide and Distance to DNA

scientific article

Incorporation of basic side chains into cryptolepine scaffold: structure-antimalarial activity relationships and mechanistic studies

scientific article published on 5 January 2011

Indolo[3,2-c]quinoline G-quadruplex stabilizers: a structural analysis of binding to the human telomeric G-quadruplex

scientific article published on 26 March 2015

Indoloquinolines as scaffolds for drug discovery.

scientific article published on January 2010

KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines.

scientific article published on 8 April 2015

N10,N11-di-alkylamine indolo[3,2-b]quinolines as hemozoin inhibitors: design, synthesis and antiplasmodial activity

scientific article published on 13 February 2015

Synthesis, G-quadruplex stabilisation, docking studies, and effect on cancer cells of indolo[3,2-b]quinolines with one, two, or three basic side chains.

scientific article published on 19 August 2013

Targeting KRAS Oncogene in Colon Cancer Cells with 7-Carboxylate Indolo[3,2-b]quinoline Tri-Alkylamine Derivatives.

scientific article published on 29 May 2015

List of works by João Lavrado