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List of works by Gennady Yegutkin

A Cell Surface Amine Oxidase Directly Controls Lymphocyte Migration

scientific article published in March 2001

A peptide inhibitor of vascular adhesion protein-1 (VAP-1) blocks leukocyte-endothelium interactions under shear stress

scientific article published on 01 August 2004

ATP release, generation and hydrolysis in exocrine pancreatic duct cells.

scientific article published on 2 October 2015

ATP-consuming and ATP-generating Enzymes Secreted by Pancreas

scientific article published in Journal of Biological Chemistry

Aberrant Circulating Levels of Purinergic Signaling Markers Are Associated With Several Key Aspects of Peripheral Atherosclerosis and Thrombosis

scientific article published on 27 March 2015

Activation of ATP/UTP-selective receptors increases blood flow and blunts sympathetic vasoconstriction in human skeletal muscle

scientific article published on 14 August 2008

Adenosine Metabolism: Emerging Concepts for Cancer Therapy

scientific article published on 01 December 2019

Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors

scientific article published on 15 October 2014

Adenosine inhibits tumor cell invasion via receptor-independent mechanisms

scientific article

Adherent leukocytes prevent adenosine formation and impair endothelial barrier function by Ecto-5'-nucleotidase/CD73-dependent mechanism

scientific article published on 21 April 2003

Alteration of 5′-nucleotidase Properties in Rat Adipose and Liver Plasma Membranes after 1 Gy Whole-body γ-irradiation

scientific article published in January 1993

Alteration of Extracellular Nucleotide Metabolism in Pseudoxanthoma Elasticum.

scientific article published on 28 February 2018

Altered purinergic signaling in CD73-deficient mice inhibits tumor progression

scientific article published in May 2011

Anti-CD73 in cancer immunotherapy: awakening new opportunities.

scientific article published on February 2016

Beneficial Role of Erythrocyte Adenosine A2B Receptor-Mediated AMP-Activated Protein Kinase Activation in High-Altitude Hypoxia

scientific article published in August 2016

CD73 facilitates EMT progression and promotes lung metastases in triple-negative breast cancer

scientific article published on 16 March 2021

CD73 is a major regulator of adenosinergic signalling in mouse brain.

scientific article

Chronic hypoxia impairs extracellular nucleotide metabolism and barrier function in pulmonary artery vasa vasorum endothelial cells

scientific article published on 16 September 2011

Compartmentalization of adenosine metabolism in cancer cells and its modulation during acute hypoxia

scientific article published on 21 April 2020

Consequences of the lack of CD73 and prostatic acid phosphatase in the lymphoid organs

scientific article

Deregulation of ocular nucleotide homeostasis in patients with diabetic retinopathy.

scientific article

Different role of CD73 in leukocyte trafficking via blood and lymph vessels

scientific article published on 23 February 2011

Dinucleotide polyphosphates contribute to purinergic signalling via inhibition of adenylate kinase activity

scientific article published in August 2008

Early prediction of persistent organ failure by soluble CD73 in patients with acute pancreatitis*.

scientific article

Ecto-5′-nucleotidase/CD73 enhances endothelial barrier function and sprouting in blood but not lymphatic vasculature

scientific article published on 15 December 2014

Endothelial cells cope with hypoxia-induced depletion of ATP via activation of cellular purine turnover and phosphotransfer networks.

scientific article published on 4 March 2018

Enzyme-coupled assays for simultaneous detection of nanomolar ATP, ADP, AMP, adenosine, inosine and pyrophosphate concentrations in extracellular fluids.

scientific article published on October 2012

Enzymes involved in metabolism of extracellular nucleotides and nucleosides: functional implications and measurement of activities.

scientific article

Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent

scientific article published on 07 February 2017

Evaluation of age-related changes of physicochemical properties and functional activity of rat adipose plasma membranes and their possible relationship

scientific article published in June 1991

Extracellular ATP formation on vascular endothelial cells is mediated by ecto-nucleotide kinase activities via phosphotransfer reactions.

scientific article

Histochemical Approach for Simultaneous Detection of Ectonucleotidase and Alkaline Phosphatase Activities in Tissues

scientific article published on 01 January 2020

IFN-beta protects from vascular leakage via up-regulation of CD73.

scientific article published in December 2007

IFN-beta regulates CD73 and adenosine expression at the blood-brain barrier.

scientific article published in October 2008

Impaired ATP-induced coronary blood flow and diminished aortic NTPDase activity precede lesion formation in apolipoprotein E-deficient mice

scientific article published on 7 November 2011

Increased intravitreal adenosine 5′-triphosphate, adenosine 5′-diphosphate and adenosine 5′-monophosphate levels in patients with proliferative diabetic retinopathy

scientific article published on 30 July 2014

Inhibition of GGTase-I and FTase disrupts cytoskeletal organization of human PC-3 prostate cancer cells

scientific article published in August 2010

Inhibitory effects of some purinergic agents on ecto-ATPase activity and pattern of stepwise ATP hydrolysis in rat liver plasma membranes

scientific article published in June 2000

Intravascular ADP and soluble nucleotidases contribute to acute prothrombotic state during vigorous exercise in humans

scientific article published in March 2007

Mechanism of action of IFN-beta in the treatment of multiple sclerosis: a special reference to CD73 and adenosine

scientific article published in September 2007

Metabolism of circulating ADP in the bloodstream is mediated via integrated actions of soluble adenylate kinase-1 and NTPDase1/CD39 activities

scientific article

MicroRNA-155 modulates P2R signaling and Th2 priming of dendritic cells during allergic airway inflammation in mice.

scientific article published on 28 May 2015

NTPDase1/CD39 and aberrant purinergic signalling in the pathogenesis of COPD.

scientific article published on 5 November 2015

Natural killer T cell dysfunction in CD39-null mice protects against concanavalin A-induced hepatitis

scientific article

Nucleotide homeostasis and purinergic nociceptive signaling in rat meninges in migraine-like conditions.

scientific article published on July 2016

Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade

scientific article

Origins of serum semicarbazide-sensitive amine oxidase

scientific article published on 3 June 2004

Postnatal development and LPS responsiveness of pulmonary adenosine receptor expression and of adenosine-metabolizing enzymes in mice

scientific article published on 4 September 2014

Pravastatin-induced improvement in coronary reactivity and circulating ATP and ADP levels in young adults with type 1 diabetes

scientific article

Primary Amine Oxidase of Escherichia coli Is a Metabolic Enzyme that Can Use a Human Leukocyte Molecule as a Substrate

scientific article

Simvastatin use associated with low intraocular ADP levels in patients with sight-threatening diabetic retinopathy

scientific article

Soluble and membrane-bound adenylate kinase and nucleotidases augment ATP-mediated inflammation in diabetic retinopathy eyes with vitreous hemorrhage

scientific article published on 07 January 2019

Steady-state binding of [ 3 H]ATP to rat liver plasma membranes and competition by various purinergic agonists and antagonists

scientific article published in August 1998

Structure-Activity Relationship of Purine and Pyrimidine Nucleotides as Ecto-5'-Nucleotidase (CD73) Inhibitors

scientific article published on 21 March 2019

Synthesis, 68Ga labeling and preliminary evaluation of DOTA peptide binding vascular adhesion protein-1: a potential PET imaging agent for diagnosing osteomyelitis

scientific article published in August 2009

The authors reply

scientific article published in July 2015

The detection of micromolar pericellular ATP pool on lymphocyte surface by using lymphoid ecto-adenylate kinase as intrinsic ATP sensor

scientific article

The effect of intravenous interferon-beta-1a (FP-1201) on lung CD73 expression and on acute respiratory distress syndrome mortality: an open-label study.

scientific article published on 23 December 2013

The evidence for two opposite, ATP-generating and ATP-consuming, extracellular pathways on endothelial and lymphoid cells.

scientific article published on October 2002

Vascular amine oxidases are needed for leukocyte extravasation into inflamed joints in vivo

scientific article published on 01 September 2006

α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5'-Nucleotidase (CD73) Inhibitors.

scientific article