List of works by Cristiana Perrotta

5-Fluorouracil causes leukocytes attraction in the peritoneal cavity by activating autophagy and HMGB1 release in colon carcinoma cells

scientific article

A Cellular System to Study the Role of Nitric Oxide in Cell Death, Survival, and Migration

scientific article published on 01 October 2005

A novel CLN8 mutation in late-infantile-onset neuronal ceroid lipofuscinosis (LINCL) reveals aspects of CLN8 neurobiological function.

scientific article published in July 2009

Acid Sphingomyelinase Downregulation Enhances Mitochondrial Fusion and Promotes Oxidative Metabolism in a Mouse Model of Melanoma ⬇️

scientific article published on 31 March 2020

Acid sphingomyelinase activity triggers microparticle release from glial cells

scientific article

Acid sphingomyelinase activity triggers microparticle release from glial cells

Acid sphingomyelinase determines melanoma progression and metastatic behaviour via the microphtalmia-associated transcription factor signalling pathway

scientific article published on 06 December 2013

Activation of endothelial nitric-oxide synthase by tumor necrosis factor-alpha: a novel pathway involving sequential activation of neutral sphingomyelinase, phosphatidylinositol-3' kinase, and Akt.

scientific article published on April 2003

An update on the assessment and management of metabolic syndrome, a growing medical emergency in paediatric populations.

scientific article

Autophagy controls neonatal myogenesis by regulating the GH-IGF1 system through a NFE2L2- and DDIT3-mediated mechanism

scientific article published in January 2019

Biological roles of Acid and neutral sphingomyelinases and their regulation by nitric oxide

scientific article published on April 2010

Caspase-8 and caspase-7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF-R1 receptosomes

scientific article

Ceramide as a target of chemotherapy: its role in apoptosis and autophagy

Climacostol reduces tumour progression in a mouse model of melanoma via the p53-dependent intrinsic apoptotic programme.

scientific article published on 07 June 2016

Current Evidence for a Role of Neuropeptides in the Regulation of Autophagy.

scientific article published on 16 May 2017

Deficient nitric oxide signalling impairs skeletal muscle growth and performance: involvement of mitochondrial dysregulation

scientific article

Drp1 overexpression induces desmin disassembling and drives kinesin-1 activation promoting mitochondrial trafficking in skeletal muscle

scientific article published on 10 February 2020

Dysfunctional autophagy induced by the pro-apoptotic natural compound climacostol in tumour cells

scientific article published on 19 December 2018

Enalapril Associated with Furosemide Induced Acute Kidney Injury in an Infant with Heart Failure. A Case Report, a Revision of the Literature and a Pharmacovigilance Database Analysis

scientific article published on 18 November 2015

Endothelial nitric oxide synthase activation by tumor necrosis factor alpha through neutral sphingomyelinase 2, sphingosine kinase 1, and sphingosine 1 phosphate receptors: a novel pathway relevant to the pathophysiology of endothelium

scientific article published on 3 November 2005

Essential role for acid sphingomyelinase-inhibited autophagy in melanoma response to cisplatin

scientific article published on 14 April 2016

Five-aminosalicylic Acid: an update for the reappraisal of an old drug

scientific article

Hormones and immunity in cancer: are thyroid hormones endocrine players in the microglia/glioma cross-talk?

scientific article published on 23 June 2015

Ibuprofen-arginine generates nitric oxide and has enhanced anti-inflammatory effects.

scientific article

Microvesicles released from microglia stimulate synaptic activity via enhanced sphingolipid metabolism.

scientific article published on 13 January 2012

Modulation of Acid Sphingomyelinase in Melanoma Reprogrammes the Tumour Immune Microenvironment

scientific article published on 26 May 2015

Natural products from aquatic eukaryotic microorganisms for cancer therapy: Perspectives on anti-tumour properties of ciliate bioactive molecules

scientific article published on 17 September 2016

Necdin is expressed in cachectic skeletal muscle to protect fibers from tumor-induced wasting

scientific article published on April 2009

Nitric Oxide Boosts Chemoimmunotherapy via Inhibition of Acid Sphingomyelinase in a Mouse Model of Melanoma

article

Nitric Oxide Generated by Tumor-Associated Macrophages Is Responsible for Cancer Resistance to Cisplatin and Correlated With Syntaxin 4 and Acid Sphingomyelinase Inhibition.

scientific article published on 29 May 2018

Nitric oxide and sphingolipids: mechanisms of interaction and role in cellular pathophysiology

scientific article

Nitric oxide confers therapeutic activity to dendritic cells in a mouse model of melanoma

scientific article published in June 2004

Nitric oxide drives embryonic myogenesis in chicken through the upregulation of myogenic differentiation factors.

scientific article published on 15 November 2013

Nitric oxide release combined with nonsteroidal antiinflammatory activity prevents muscular dystrophy pathology and enhances stem cell therapy

scholarly article

Nitric oxide, ceramide and sphingomyelinase-coupled receptors: a tale of enzymes and messengers coordinating cell death, survival and differentiation

scientific article

On the Connection Between Autoimmunity, tic Disorders and Obsessive-Compulsive Disorders: A Meta-Analysis on Anti-Streptolysin O Titres

scientific article published on 05 August 2014

Prevalence of respiratory colonisations and related antibiotic resistances among paediatric tracheostomised patients of a long-term rehabilitation centre in Italy.

scientific article published on 9 August 2014

Reversal of Defective Mitochondrial Biogenesis in Limb-Girdle Muscular Dystrophy 2D by Independent Modulation of Histone and PGC-1α Acetylation

scientific article published in December 2016

Role of caspases in CD95-induced biphasic activation of acid sphingomyelinase

scientific article published on 16 February 2017

Silver nanoparticles-induced cytotoxicity requires ERK activation in human bladder carcinoma cells

scientific article published on 3 July 2015

Skeletal muscle homeostasis in duchenne muscular dystrophy: modulating autophagy as a promising therapeutic strategy

scientific article

Sphingolipids and brain resident macrophages in neuroinflammation: an emerging aspect of nervous system pathology

scientific article published on 02 September 2013

Synergism of nitric oxide and maturation signals on human dendritic cells occurs through a cyclic GMP-dependent pathway

scientific article

Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function

scientific article

The Natural Compound Climacostol as a Prodrug Strategy Based on pH Activation for Efficient Delivery of Cytotoxic Small Agents

scientific article published on 28 June 2019

The emerging role of acid sphingomyelinase in autophagy

scientific article published on May 2015

The epidemiological profile of ASIA syndrome after HPV vaccination: an evaluation based on the Vaccine Adverse Event Reporting Systems

article

The first steps towards the era of personalised vaccinology: predicting adverse reactions

scientific article published on 07 October 2014

The protein pheromone Er-1 of the ciliate Euplotes raikovi stimulates human T-cell activity: involvement of interleukin-2 system.

scientific article

The role of Toll-like receptor 4 polymorphisms in vaccine immune response

scientific article published on 31 March 2015

The thyroid hormone triiodothyronine controls macrophage maturation and functions: protective role during inflammation.

scientific article

Vaccine-Drug Interactions: Cytokines, Cytochromes, and Molecular Mechanisms.

scientific article published on 04 August 2015

XIAP as a Target of New Small Organic Natural Molecules Inducing Human Cancer Cell Death

scientific article published on 09 September 2019

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