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List of works by Ralf Max Leonhardt

A role for UDP-glucose glycoprotein glucosyltransferase in expression and quality control of MHC class I molecules

scientific article

Biogenesis of functional antigenic peptide transporter TAP requires assembly of pre-existing TAP1 with newly synthesized TAP2

scientific journal article

Cancer immunotherapy takes a multi-faceted approach to kick the immune system into gear.

scientific article published on December 2011

Critical residues in the PMEL/Pmel17 N-terminus direct the hierarchical assembly of melanosomal fibrils

scientific article published on 6 February 2013

Critical role for the tapasin-docking site of TAP2 in the functional integrity of the MHC class I-peptide-loading complex.

scientific article published on October 2005

Cytosolic Processing Governs TAP-Independent Presentation of a Critical Melanoma Antigen

scientific article published on 22 August 2018

Endoplasmic reticulum export, subcellular distribution, and fibril formation by Pmel17 require an intact N-terminal domain junction.

scientific article

Functional role of C-terminal sequence elements in the transporter associated with antigen processing

scientific journal article

Functional significance of tapasin membrane association and disulfide linkage to ERp57 in MHC class I presentation

scientific article

Hydrophobic Interactions Are Key To Drive the Association of Tapasin with Peptide Transporter Subunit TAP2.

scientific article published on 30 October 2015

Identification of key amino acid residues that determine the ability of high risk HPV16-E7 to dysregulate major histocompatibility complex class I expression.

scientific article published on 14 February 2011

Inefficient exogenous loading of a tapasin-dependent peptide onto HLA-B*44:02 can be improved by acid treatment or fixation of target cells

scientific article published on June 2012

Melanosomal formation of PMEL core amyloid is driven by aromatic residues

scientific article published on 08 March 2017

Molecular architecture of the TAP-associated MHC class I peptide-loading complex

scientific article

Non-Synonymous variants in premelanosome protein (PMEL) cause ocular pigment dispersion and pigmentary glaucoma

scientific article published on 01 April 2019

Post-endoplasmic reticulum rescue of unstable MHC class I requires proprotein convertase PC7.

scientific article

Proprotein convertases process Pmel17 during secretion

scientific article

Repeat domain-associated O-glycans govern PMEL fibrillar sheet architecture

scientific article published on 15 April 2019

Severe tryptophan starvation blocks onset of conventional persistence and reduces reactivation of Chlamydia trachomatis

scientific article

Three tapasin docking sites in TAP cooperate to facilitate transporter stabilization and heterodimerization

scientific article published on 5 February 2014

Xenophagic pathways and their bacterial subversion in cellular self-defense - παντα ρει - everything is in flux.

scientific article published on 2 November 2017