List of works - Bryan Knuckley

A fluopol-ABPP HTS assay to identify PAD inhibitors ⬇️

scientific article published on August 25, 2010

A fluoroacetamidine-based inactivator of protein arginine deiminase 4: design, synthesis, and in vitro and in vivo evaluation

scientific article published on February 2006

Activity-based protein profiling reagents for protein arginine deiminase 4 (PAD4): synthesis and in vitro evaluation of a fluorescently labeled probe

scientific article published on November 2006

Design, synthesis, and in vitro evaluation of an activity-based protein profiling (ABPP) probe targeting agmatine deiminases

scientific article published on 25 July 2014

Development of a Plate-Based Screening Assay to Investigate the Substrate Specificity of the PRMT Family of Enzymes.

scientific article published on 7 August 2015

Development of a clickable activity-based protein profiling (ABPP) probe for agmatine deiminases

scientific article

Felty's syndrome autoantibodies bind to deiminated histones and neutrophil extracellular chromatin traps

scientific article published on 27 October 2011

Ibotenic acid lesions to ventrolateral thalamic nuclei disrupts trace and delay eyeblink conditioning in rabbits

scientific article published on 31 January 2007

Inhibitors and inactivators of protein arginine deiminase 4: functional and structural characterization.

scientific article published on October 2006

Mechanistic studies of protein arginine deiminase 2: evidence for a substrate-assisted mechanism

scientific article published on 03 July 2014

Mechanistic studies of the agmatine deiminase from Listeria monocytogenes ⬇️

scientific article published on 31 March 2016

N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis.

scientific article

Prefrontal control of trace eyeblink conditioning in rabbits (Oryctolagus cuniculus) II: effects of type of unconditioned stimulus (airpuff vs. periorbital shock) and unconditioned stimulus intensity

scientific article published on 24 August 2008

Prefrontal control of trace versus delay eyeblink conditioning: role of the unconditioned stimulus in rabbits (Oryctolagus cuniculus).

scientific article published in October 2006

Probing adenylation: using a fluorescently labelled ATP probe to directly label and immunoprecipitate VopS substrates.

scientific article published on 28 March 2012

Profiling Protein Arginine Deiminase 4 (PAD4): a novel screen to identify PAD4 inhibitors

scientific article published on 13 October 2007

Protein arginine deiminase 4: evidence for a reverse protonation mechanism

scientific article

Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3.

scientific article

Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor ⬇️

scientific article published on March 17, 2011

The development and characterization of a chemical probe targeting PRMT1 over PRMT5

scientific article published on 04 December 2018

Two Distinct Cyclodipeptide Synthases from a Marine Actinomycete Catalyze Biosynthesis of the Same Diketopiperazine Natural Product.

scientific article

List of works by Bryan Knuckley

A fluopol-ABPP HTS assay to identify PAD inhibitors ⬇️

A fluoroacetamidine-based inactivator of protein arginine deiminase 4: design, synthesis, and in vitro and in vivo evaluation

Activity-based protein profiling reagents for protein arginine deiminase 4 (PAD4): synthesis and in vitro evaluation of a fluorescently labeled probe

Design, synthesis, and in vitro evaluation of an activity-based protein profiling (ABPP) probe targeting agmatine deiminases

Development of a Plate-Based Screening Assay to Investigate the Substrate Specificity of the PRMT Family of Enzymes.

Development of a clickable activity-based protein profiling (ABPP) probe for agmatine deiminases

Felty's syndrome autoantibodies bind to deiminated histones and neutrophil extracellular chromatin traps

Ibotenic acid lesions to ventrolateral thalamic nuclei disrupts trace and delay eyeblink conditioning in rabbits

Inhibitors and inactivators of protein arginine deiminase 4: functional and structural characterization.

Mechanistic studies of protein arginine deiminase 2: evidence for a substrate-assisted mechanism

Mechanistic studies of the agmatine deiminase from Listeria monocytogenes ⬇️

N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis.

Prefrontal control of trace eyeblink conditioning in rabbits (Oryctolagus cuniculus) II: effects of type of unconditioned stimulus (airpuff vs. periorbital shock) and unconditioned stimulus intensity

Prefrontal control of trace versus delay eyeblink conditioning: role of the unconditioned stimulus in rabbits (Oryctolagus cuniculus).

Probing adenylation: using a fluorescently labelled ATP probe to directly label and immunoprecipitate VopS substrates.

Profiling Protein Arginine Deiminase 4 (PAD4): a novel screen to identify PAD4 inhibitors

Protein arginine deiminase 4: evidence for a reverse protonation mechanism

Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3.

Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor ⬇️

The development and characterization of a chemical probe targeting PRMT1 over PRMT5

Two Distinct Cyclodipeptide Synthases from a Marine Actinomycete Catalyze Biosynthesis of the Same Diketopiperazine Natural Product.