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List of works by Patrick Legembre

A Novel Covalent mTOR Inhibitor, DHM25, Shows in Vivo Antitumor Activity against Triple-Negative Breast Cancer Cells

scientific article published on 3 August 2015

Actin-independent exclusion of CD95 by PI3K/AKT signalling: implications for apoptosis

scientific article published on 4 July 2011

Amplification of Fas-mediated apoptosis in type II cells via microdomain recruitment

scientific article

An atypical necrotic signal induced by immunosuppressive and anti-viral agents

scientific article

An insight into the role of the death receptor CD95 throughout pregnancy: Guardian, facilitator, or foe

scientific article published on 31 January 2019

Boyden Chamber Assay to Study of Cell Migration Induced by Metalloprotease Cleaved-CD95L.

scientific article

CD95 Stimulation with CD95L and DISC Analysis

scientific article published on January 2017

CD95 engagement mediates actin-independent and -dependent apoptotic signals

scientific article published on 14 August 2009

CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells

scientific article

CD95 triggers Orai1-mediated localized Ca2+ entry, regulates recruitment of protein kinase C (PKC) β2, and prevents death-inducing signaling complex formation

scientific article published on 7 November 2011

CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice

scientific article published on July 2016

CD95-mediated cell signaling in cancer: mutations and post-translational modulations

scientific article

CD95/Fas and metastatic disease: What does not kill you makes you stronger

scientific article published on 06 June 2019

CD95/Fas protects triple negative breast cancer from anti-tumor activity of NK cells

scientific article published on 29 October 2021

CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism

scientific article published on 01 December 2021

CD95/Fas, Non-Apoptotic Signaling Pathways, and Kinases

scientific article published on 27 September 2017

CD95L cell surface cleavage triggers a prometastatic signaling pathway in triple-negative breast cancer

scientific article published on 26 September 2013

Chemotherapy with ceramide in TNBC.

scientific article published on 21 August 2015

Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells.

scientific article published on 4 March 2010

Correction to A Novel Covalent mTOR Inhibitor, DHM25, Shows in Vivo Antitumor Activity against Triple-Negative Breast Cancer Cells

correction of a scholarly article

Disrupting the CD95–PLCγ1 interaction prevents Th17-driven inflammation

scientific article published on 14 November 2018

Does CD95 have tumor promoting activities?

scientific article

Does calcium contribute to the CD95 signaling pathway?

scientific article published on July 2011

Dominant-negative Fas mutation is reversed by down-expression of c-FLIP.

scientific article published on January 2007

Downregulation of ceramide synthase-6 during epithelial-to-mesenchymal transition reduces plasma membrane fluidity and cancer cell motility

scientific article published on 17 March 2014

Erratum

scholarly article published in Methods in Molecular Biology

Flt3-ligand induces adhesion of haematopoietic progenitor cells via a very late antigen (VLA)-4- and VLA-5-dependent mechanism

scientific article published on 01 March 2003

Functional characterization of a chimeric soluble Fas ligand polymer with in vivo anti-tumor activity

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

HIV protease inhibitors and autoimmunity: An odd, but promising idea

scientific article published on 09 August 2019

Identification of SNF1/AMP kinase-related kinase as an NF-kappaB-regulated anti-apoptotic kinase involved in CD95-induced motility and invasiveness

scientific article

Induction of apoptosis and activation of NF-kappaB by CD95 require different signalling thresholds

scientific article

Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy

scientific article published in Nature Communications

Investigation of Phospholipase Cγ1 Interaction with SLP76 Using Molecular Modeling Methods for Identifying Novel Inhibitors

scientific article published on 23 September 2019

Localization of Fas/CD95 into the lipid rafts on down-modulation of the phosphatidylinositol 3-kinase signaling pathway

scientific article

Myeloid-derived suppressor cell, arginase-1, IL-17 and cl-CD95L: an explosive cocktail in lupus?

scientific article published on December 2016

Nonapoptotic functions of Fas/CD95 in the immune response

scientific article

Potentiation of Fas-mediated apoptosis by an engineered glycosylphosphatidylinositol-linked Fas.

scientific article published in March 2002

Precise mapping of the CD95 pre-ligand assembly domain

scientific article

Proximity Ligation Assay (PLA) to Evaluate DISC and MISC Composition

scientific article published in January 2017

Redistribution of CD95 into the lipid rafts to treat cancer cells?

scientific article published on January 2010

Review of PI3K/mTOR Inhibitors Entering Clinical Trials to Treat Triple Negative Breast Cancers

scientific article published on 19 May 2016

Rewinding the DISC.

scientific article published on January 2008

S-nitrosylation of the death receptor fas promotes fas ligand-mediated apoptosis in cancer cells.

scientific article published on 24 February 2011

Serum CD95L Level Correlates with Tumor Immune Infiltration and Is a Positive Prognostic Marker for Advanced High-Grade Serous Ovarian Cancer

scientific article published on 19 September 2019

Sphingolipids modulate the epithelial-mesenchymal transition in cancer.

scientific article published on 12 October 2015

Staphylococcus aureus induces DNA damage in host cell

scientific article published on 22 May 2019

Staphylococcus aureus-induced G2/M phase transition delay in host epithelial cells increases bacterial infective efficiency

scientific article

Study of the CD95-Mediated Non-apoptotic Signaling Pathway: PI3K.

scientific article

Synthesis of peptidomimetics and chemo-biological tools for CD95/PLCγ1 interaction analysis

scientific article published on 05 July 2019

TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress

scientific article published on 27 December 2016

The CD95/CD95L signaling pathway: a role in carcinogenesis

scientific article published on 26 April 2014

The HA tag is cleaved and loses immunoreactivity during apoptosis.

scientific article

The cleaved FAS ligand activates the Na(+)/H(+) exchanger NHE1 through Akt/ROCK1 to stimulate cell motility

scientific article

The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway

scientific article published in June 2011

The necrotic signal induced by mycophenolic acid overcomes apoptosis-resistance in tumor cells

scientific article

The plasma membrane: a catalyst in the decision to die or not to die?

scientific article published on 01 September 2011

Tumor analysis: freeze-thawing cycle of triple-negative breast cancer cells alters tumor CD24/CD44 profiles and the percentage of tumor-infiltrating immune cells.

scientific article

Two CD95 tumor classes with different sensitivities to antitumor drugs

scientific article

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