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List of works by César Nombela

A genomic approach for the identification and classification of genes involved in cell wall formation and its regulation in Saccharomyces cerevisiae

scientific article

A new system for the release of heterologous proteins from yeast based on mutant strains deficient in cell integrity

scientific article published in November 1994

A novel connection between the Cell Wall Integrity and the PKA pathways regulates cell wall stress response in yeast

scientific article

A novel connection between the yeast Cdc42 GTPase and the Slt2-mediated cell integrity pathway identified through the effect of secreted Salmonella GTPase modulators.

scientific article published on 16 May 2002

A novel family of cell wall-related proteins regulated differently during the yeast life cycle.

scientific article

A protein kinase gene complements the lytic phenotype of Saccharomyces cerevisiae lyt2 mutants.

scientific article published on November 1991

A proteomic approach for the study of Saccharomyces cerevisiae cell wall biogenesis

scientific article published on 01 October 2000

A proteomic approach to study Salmonella typhi periplasmic proteins altered by a lack of the DsbA thiol: disulfide isomerase

scientific article published in February 2004

A reorganized Candida albicans DNA sequence promoting homologous non-integrative genetic transformation

scientific article

A single-copy suppressor of the Saccharomyces cerevisae late-mitotic mutants cdc15 and dbf2 is encoded by the Candida albicans CDC14 gene.

scientific article

A yeast strain biosensor to detect cell wall-perturbing agents

scientific article published on 30 October 2007

Activation of the yeast cell wall integrity MAPK pathway by zymolyase depends on protease and glucanase activities and requires the mucin-like protein Hkr1 but not Msb2.

scientific article

Activity of the yeast MAP kinase homologue Slt2 is critically required for cell integrity at 37 degrees C.

scientific article

An encrusted cystitis caused by Corynebacterium urealyticum in a dog.

scientific article published in February 1995

Analysis of Candida albicans plasma membrane proteome

scientific article published in October 2009

Analysis of the Candida albicans proteome. I. Strategies and applications

scientific article

Analysis of the Candida albicans proteome. II. Protein information technology on the Net (update 2002).

scientific article

Applications of flow cytometry to clinical microbiology

scientific article

CRR1, a gene encoding a putative transglycosidase, is required for proper spore wall assembly in Saccharomyces cerevisiae.

scientific article

Candida albicans Shaving to Profile Human Serum Proteins on Hyphal Surface

scientific article published on 8 December 2015

Candida albicans actively modulates intracellular membrane trafficking in mouse macrophage phagosomes.

scientific article

Candida albicans exoglucanase as a reporter gene in Schizosaccharomyces pombe

article

Candida albicans induces pro-inflammatory and anti-apoptotic signals in macrophages as revealed by quantitative proteomics and phosphoproteomics

scientific article published on 5 July 2013

Cell surface shaving of Candida albicans biofilms, hyphae, and yeast form cells

scientific article published on 01 August 2012

Characterization of SKM1, a Saccharomyces cerevisiae gene encoding a novel Ste20/PAK-like protein kinase.

scientific article

Characterization of domains in the yeast MAP kinase Slt2 (Mpk1) required for functional activity and in vivo interaction with protein kinases Mkk1 and Mkk2

scientific article published on 01 September 1995

Characterization of natural peptide ligands from HLA-DP2: new insights into HLA-DP peptide-binding motifs.

scientific article

Characterization of sensor-specific stress response by transcriptional profiling of wsc1 and mid2 deletion strains and chimeric sensors in Saccharomyces cerevisiae.

scientific article published on 20 October 2010

Choline-binding domain as a novel affinity tag for purification of fusion proteins produced in Pichia pastoris.

scientific article published in July 2001

Chromatin remodeling by the SWI/SNF complex is essential for transcription mediated by the yeast cell wall integrity MAPK pathway ⬇️

scientific article published on May 23, 2012

Contribution of the antibodies response induced by a low virulent Candida albicans strain in protection against systemic candidiasis

scientific article published on April 2004

Cooperation between SAGA and SWI/SNF complexes is required for efficient transcriptional responses regulated by the yeast MAPK Slt2.

scientific article published on 25 April 2016

Decoding serological response to Candida cell wall immunome into novel diagnostic, prognostic, and therapeutic candidates for systemic candidiasis by proteomic and bioinformatic analyses

scientific article

Differential protein expression of murine macrophages upon interaction with Candida albicans

scientific article published on April 2006

Enteropathogenic Escherichia coli type III effectors alter cytoskeletal function and signalling in Saccharomyces cerevisiae

scientific article published in September 2005

Estradiol impairs the Th17 immune response against Candida albicans

article

Fe de errores de «La proteómica, un nuevo reto para la microbiología clínica»

Flow cytometric analysis of Saccharomyces cerevisiae autolytic mutants and protoplasts

scientific article published on 01 January 1992

Functional analysis of HLA-DP polymorphism: a crucial role for DPbeta residues 9, 11, 35, 55, 56, 69 and 84-87 in T cell allorecognition and peptide binding

scientific article published in May 2003

Functional characterization of human and fungal MAP kinases in Saccharomyces cerevisiae

scientific article published on 01 September 2007

Fungal cell wall biogenesis: building a dynamic interface with the environment.

scientific article published in October 2004

Gel and gel-free proteomics to identify Saccharomyces cerevisiae cell surface proteins.

scientific article published on 20 February 2010

Genetic and proteomic evidences support the localization of yeast enolase in the cell surface

scientific article

Genome-wide survey of yeast mutations leading to activation of the yeast cell integrity MAPK pathway: novel insights into diverse MAPK outcomes.

scientific article

Genomic profiling of fungal cell wall-interfering compounds: identification of a common gene signature.

scientific article published on 5 September 2015

HLA-DPbeta residue 69 plays a crucial role in allorecognition.

scientific article published on July 1998

Identification of Candida albicans exposed surface proteins in vivo by a rapid proteomic approach.

scientific article published on 16 February 2010

Identification of a nuclear export signal in the KSHV latent protein LANA2 mediating its export from the nucleus

scientific article published on 7 October 2005

Immunoproteomic analysis of the protective response obtained from vaccination with Candida albicans ecm33 cell wall mutant in mice

scientific article published on 01 July 2008

Integrated proteomics and genomics strategies bring new insight into Candida albicans response upon macrophage interaction

scientific article published on 12 December 2006

Julio R. Villanueva, microbiologist, researcher, and mentor of generations of scientists.

scientific article published in December 2017

La proteómica, un nuevo reto para la microbiología clínica

scientific article published on 01 October 2010

Large-scale identification of putative exported proteins in Candida albicans by genetic selection

scientific article published on August 2002

Low virulent strains of Candida albicans: unravelling the antigens for a future vaccine

scientific article

MAP kinase pathways as regulators of fungal virulence.

scientific article published on 23 February 2007

Morphogenesis beyond cytokinetic arrest in Saccharomyces cerevisiae.

scientific article

Non-conventional protein secretionin yeast

scientific article published on 13 December 2005

PST1 and ECM33 encode two yeast cell surface GPI proteins important for cell wall integrity

scientific article

Pim1, a MAP kinase involved in cell wall integrity in Pichia pastoris

scientific article published in June 2001

Prediction of the clinical outcome in invasive candidiasis patients based on molecular fingerprints of five anti-Candida antibodies in serum

scientific article

Protein phosphatases in MAPK signalling: we keep learning from yeast.

scientific article

Proteomic analysis of cytoplasmic and surface proteins from yeast cells, hyphae, and biofilms of Candida albicans

scientific article

Proteomic analysis of detergent-resistant membranes from Candida albicans.

scientific article

Proteomics Unravels Extracellular Vesicles as Carriers of Classical Cytoplasmic Proteins in Candida albicans

scientific article published on 12 November 2014

Proteomics of RAW 264.7 macrophages upon interaction with heat-inactivated Candida albicans cells unravel an anti-inflammatory response

scientific journal article

Proteomics-based identification of novel Candida albicans antigens for diagnosis of systemic candidiasis in patients with underlying hematological malignancies

scientific article

Proteopathogen, a protein database for studying Candida albicans--host interaction

scientific article

Quantitative Proteome and Acidic Subproteome Profiling of Candida albicans Yeast-to-Hypha Transition

scientific article published on 31 December 2010

Regulatory mechanisms for modulation of signaling through the cell integrity Slt2-mediated pathway in Saccharomyces cerevisiae

scientific article

Reliability of antibodies to Candida methionine synthase for diagnosis, prognosis and risk stratification in systemic candidiasis: A generic strategy for the prototype development phase of proteomic markers

scientific article published on 24 September 2007

Rlm1 mediates positive autoregulatory transcriptional feedback that is essential for Slt2-dependent gene expression.

scientific article

Sequential fractionation and two-dimensional gel analysis unravels the complexity of the dimorphic fungus Candida albicans cell wall proteome

scientific article

Serological proteome analysis to identify systemic candidiasis patients in the intensive care unit: Analytical, diagnostic and prognostic validation of anti-Candida enolase antibodies on quantitative clinical platforms

scientific article published on 01 April 2008

Seroprofiling at the Candida albicans protein species level unveils an accurate molecular discriminator for candidemia

scientific article published on 17 October 2015

Serum antibody signature directed against Candida albicans Hsp90 and enolase detects invasive candidiasis in non-neutropenic patients

scientific article published on 14 October 2014

Strategies for the identification of virulence determinants in human pathogenic fungi.

scientific article

Structural and functional analysis of yeast Crh1 and Crh2 transglycosylases.

scientific article published on 19 January 2015

Sub-proteomic study on macrophage response to Candida albicans unravels new proteins involved in the host defense against the fungus

scientific article

The 'yeast cell wall chip' - a tool to analyse the regulation of cell wall biogenesis in Saccharomyces cerevisiae.

scientific article

The Cek1 and Hog1 mitogen-activated protein kinases play complementary roles in cell wall biogenesis and chlamydospore formation in the fungal pathogen Candida albicans.

scientific article published on February 2006

The GPI-anchored protein CaEcm33p is required for cell wall integrity, morphogenesis and virulence in Candida albicans

scientific article

The Hog1 MAP kinase controls respiratory metabolism in the fungal pathogen Candida albicans.

scientific article published on February 2009

The Hog1 mitogen-activated protein kinase is essential in the oxidative stress response and chlamydospore formation in Candida albicans.

scientific article

The MAP kinase Mkc1p is activated under different stress conditions in Candida albicans.

scientific article published in August 2005

The MAP kinase signal transduction network in Candida albicans.

scientific article

The Pbs2 MAP kinase kinase is essential for the oxidative-stress response in the fungal pathogen Candida albicans

scientific article published in April 2005

The Sho1 adaptor protein links oxidative stress to morphogenesis and cell wall biosynthesis in the fungal pathogen Candida albicans.

scientific article

The complete sequence of a 9037 bp DNA fragment of the right arm of Saccharomyces cerevisiae chromosome VII.

scientific article published on May 1995

The deletion of six ORFs of unknown function from Saccharomyces cerevisiae chromosome VII reveals two essential genes: YGR195w and YGR198w

scientific article published on 01 June 1998

The high osmotic response and cell wall integrity pathways cooperate to regulate transcriptional responses to zymolyase-induced cell wall stress in Saccharomyces cerevisiae

scientific article published on 20 February 2009

The importance of the phagocytes' innate response in resolution of the infection induced by a low virulent Candida albicans mutant.

scientific article published in September 2005

The role of HLA-DP beta residue 69 in the definition of antibody-binding epitopes

scientific article published on 01 July 1995

The role of the cell wall in fungal pathogenesis.

scientific article

The sequential activation of the yeast HOG and SLT2 pathways is required for cell survival to cell wall stress

scientific article published on 9 January 2008

Top-down characterization data on the speciation of the Candida albicans immunome in candidemia

scientific article

Two different NO-dependent mechanisms account for the low virulence of a non-mycelial morphological mutant of Candida albicans

scientific article

Two-dimensional reference map of Candida albicans hyphal forms.

scientific article published in February 2004

Yeast exo-beta-glucanases can be used as efficient and readily detectable reporter genes in Saccharomyces cerevisiae

scientific article published on 01 June 1994

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