List of works - Naohisa Hosomi

17β-Estradiol regulates scavenger receptor class BI gene expression via protein kinase C in vascular endothelial cells.

scientific article published on 18 December 2013

A case of rheumatoid arthritis complicated by demyelination in both cerebral cortex and spinal cord during etanercept therapy

scientific article published on 15 April 2008

Abcb1a and Abcb1b expression in senescence-accelerated mouse (SAM).

scientific article

Acute improvement of cardiac efficiency measured by 11C-acetate PET after cardiac resynchronization therapy and clinical outcome

scientific article published on 4 December 2009

Age-related changes in P-glycoprotein expression in senescence-accelerated mouse

scientific article published in December 2009

Age-related decrease in inferior vena cava diameter measured with echocardiography

scientific article published on 01 October 2010

Alpha2-macroglobulin as a promising biomarker for cerebral small vessel disease in acute ischemic stroke patients.

scientific article published on 23 July 2013

Alteration in aortic wall stiffness and accumulation of collagen during the prediabetic stage of type II diabetes mellitus in rats

scientific article published on 01 December 1999

Analysis of association between brain natriuretic peptide levels and blood pressure variability

scientific article

Angiotensin II induces human astrocyte senescence through reactive oxygen species production

scientific article published on 27 January 2011

Angiotensin type 1 receptor blockage improves ischemic injury following transient focal cerebral ischemia

scientific article published in January 2005

Aortic annular velocity assessed by tissue Doppler echocardiography as a potential parameter of arterial stiffness

scientific article published on 01 June 2010

Association between arterial stiffness and pulmonary function in hypertensive patients

scientific article published on 24 November 2011

Association between bone mineral density and arterial stiffness in hypertensive patients

scientific article published in January 2011

Association between echocardiographic parameters and brain natriuretic peptide levels in treated hypertensive patients

scientific article published on 30 March 2011

Association between high-sensitivity C-reactive protein and left ventricular diastolic function assessed by echocardiography in patients with cardiovascular risk factors

scientific article published in January 2011

Association between left ventricular hypertrophy and changes in arterial stiffness during hypertensive treatment

scientific article published on 12 July 2013

Association between oxidative stress assessed by urinary 8-hydroxydeoxyguanosine and the cardiac function in hypertensive patients without overt heart disease

scientific article published on 6 September 2012

Association between stroke lesions and videofluoroscopic findings in acute stroke patients

scientific article published on 26 September 2020

Association of cardio-ankle vascular index with brain natriuretic peptide levels in hypertension

scientific article published on 07 November 2011

Association of plasma adrenomedullin with carotid atherosclerosis in chronic ischemic stroke

scientific article published on 01 November 2001

Association of serum anti-periodontal pathogen antibody with ischemic stroke

scientific article published on 29 November 2012

Augmentation of intrarenal angiotensin II levels in uninephrectomized aldosterone/salt-treated hypertensive rats; renoprotective effects of an ultrahigh dose of olmesartan

scientific article published on 01 March 2006

Axonal damage in acute cerebral infarction showing ADC reduction

scientific article published on 27 March 2010

Blood pressure variability and prognosis in acute ischemic stroke with vascular compression on the rostral ventrolateral medulla (RVLM)

scientific article published on 24 February 2011

Brain natriuretic peptide as a surrogate marker for cardioembolic stroke with paroxysmal atrial fibrillation

scientific article published on 18 September 2008

CD36 expression in the brains of SAMP8.

scientific article published on 9 August 2012

Cancer-associated ischemic stroke is associated with elevated D-dimer and fibrin degradation product levels in acute ischemic stroke with advanced cancer

scientific article published on 10 January 2012

Cardiac diastolic dysfunction is associated with cerebral white matter lesions in elderly patients with risk factors for atherosclerosis

scientific article published in October 2008

Carotid turbulent flow observed by convergent color Doppler flowmetry in silent cerebral infarction

scientific article published in April 2002

Cerebellar diaschisis in pontine infarctions: a report of five cases

scientific article published on 01 May 1995

Clinical significance of differences between home and clinic systolic blood pressure readings in patients with hypertension

scientific article

Comparison of central blood pressure and cardio-ankle vascular index for association with cardiac function in treated hypertensive patients.

scientific article

Comparison of magnetic resonance imaging and transesophageal echocardiography in detection of thrombus in the left atrial appendage

scientific article published on 11 September 2003

Correlation of arterial stiffness to left ventricular function in patients with reduced ejection fraction

scientific article published on 01 November 2011

Decline of plasma brain natriuretic peptide during enzyme replacement therapy in a female patient with heterozygous Fabry's disease

scientific article published in March 2009

Differences in left ventricular hypertrophy and dysfunction between patients with cerebral hemorrhage and those with cerebral infarction

scientific article published in June 2008

Differential effects of neonatal maternal separation on the expression of neurotrophic factors in rat brain. II: Regional differences in the cerebellum versus the cerebral cortex

scientific article published in January 2013

Do RAS inhibitors protect the brain from cerebral ischemic injury?

scientific article published on May 2013

Dural arteriovenous fistula presenting with progressive dementia and parkinsonism

scientific article published on 2 June 2014

Early detection of hypertension in a patient treated with sunitinib by measuring cardio-ankle vascular index.

scientific article published in June 2009

Early postnatal maternal separation causes alterations in the expression of β3-adrenergic receptor in rat adipose tissue suggesting long-term influence on obesity

scientific article published on 9 November 2013

Echocardiographic assessment of the cardio-renal connection: is left ventricular hypertrophy or diastolic function more closely correlated with estimated glomerular filtration rate in patients with cardiovascular risk factors?

scientific article published in January 2010

Effects of adrenomedullin on cardiac oxidative stress and collagen accumulation in aldosterone-dependent malignant hypertensive rats

scientific article published on 14 June 2006

Effects of pravastatin sodium and simvastatin on plasma fibrinogen level and blood rheology in type II hyperlipoproteinemia.

scientific article published in May 1996

Effects of troglitazone on collagen accumulation and distensibility of aortic wall in prestage of non-insulin-dependent diabetes mellitus of Otsuka Long-Evans Tokushima Fatty rats.

scientific article published in January 2000

Efficacy of anti-coagulant treatment with argatroban on cardioembolic stroke

scientific article published on 09 April 2007

Elevated brachial-ankle pulse wave velocity is associated with left ventricular hypertrophy in hypertensive patients after stroke

scientific article

Genome-wide response to antihypertensive medication using home blood pressure measurements: a pilot study nested within the HOMED-BP study

scientific article published in November 2013

Hyperglycemia suppresses ABCA1 expression in vascular smooth muscle cells

scientific article published on 25 January 2010

Increased blood pressure variability during the subacute phase of ischemic stroke is associated with poor functional outcomes at 3 months

scientific article published on 21 January 2020

Independent determinants of the Tei index in hypertensive patients with preserved left ventricular systolic function

scientific article published on 01 May 2009

Induced hypertension treatment to improve cerebral ischemic injury after transient forebrain ischemia

scientific article

Influences of hypertension and diabetes on normal age-related changes in left ventricular function as assessed by tissue Doppler echocardiography

scientific article published on 01 July 2009

Inhibitory effects of a dihydropyridine calcium channel blocker on renal injury in aldosterone-infused rats

scientific article published in September 2009

Involvement of mineralocorticoid receptor in high glucose-induced big mitogen-activated protein kinase 1 activation and mesangial cell proliferation

scientific article published in March 2010

Isolated unilateral hypoglossal nerve paralysis caused by internal carotid artery dissection

scientific article published on 01 August 2014

Mechanical stretch augments insulin-induced vascular smooth muscle cell proliferation by insulin-like growth factor-1 receptor

scientific journal article

Mechanical stretch potentiates angiotensin II-induced proliferation in spontaneously hypertensive rat vascular smooth muscle cells

scientific journal article

Microglial cell activation is a source of metalloproteinase generation during hemorrhagic transformation.

scientific article

Neonatal repetitive maternal separation causes long-lasting alterations in various neurotrophic factor expression in the cerebral cortex of rats

scientific article published on 16 February 2012

Plasma brain natriuretic peptide as a surrogate marker for cardioembolic stroke

scientific article

Possible contribution of the non-proteolytic activation of prorenin to the development of insulin resistance in fructose-fed rats.

scientific article

Possible involvement of Rho-kinase in aldosterone-induced vascular smooth muscle cell remodeling

scientific article published in July 2008

Predictors of intracerebral hemorrhage severity and its outcome in Japanese stroke patients

scientific article published on 15 November 2008

Prorenin induces vascular smooth muscle cell proliferation and hypertrophy via epidermal growth factor receptor-mediated extracellular signal-regulated kinase and Akt activation pathway

scientific article published on 01 April 2011

RAGE, LDL receptor, and LRP1 expression in the brains of SAMP8.

scientific article published on 17 June 2009

Rationale, design, and baseline features of a randomized controlled trial to assess the effects of statin for the secondary prevention of stroke: the Japan Statin Treatment Against Recurrent Stroke (J-STARS)

scientific article

Reduced bone mineral density in hypertensive patients is associated with left ventricular diastolic dysfunction, not left ventricular hypertrophy

scientific article published on 03 October 2011

Relation of postischemic delayed hypoperfusion and cerebral edema after transient forebrain ischemia

scientific article published on 01 May 2007

Relationship between arterial stiffness and variability in systolic blood pressure during a single clinic visit in patients with hypertension

scientific article published on 21 February 2013

Renin-angiotensin system in neuronal disease

scientific article

Reversible magnetic resonance imaging changes associated with hypoglycemia. Case report

scientific article published on January 2010

Safety evaluation of substituting clopidogrel for ticlopidine in Japanese patients with ischemic stroke--Hiroshima ticlopidine, clopidogrel safe exchange trial

scientific article published on 20 February 2014

Short-term ethanol exposure causes imbalanced neurotrophic factor allocation in the basal forebrain cholinergic system: a novel insight into understanding the initial processes of alcohol addiction

scientific article published on 6 September 2013

Short-term exposure to ethanol causes a differential response between nerve growth factor and brain-derived neurotrophic factor ligand/receptor systems in the mouse cerebellum

scientific article published in January 2010

Smoking, fasting serum insulin, and obesity are the predictors of carotid atherosclerosis in relatively young subjects

scientific article published in December 2007

Strict angiotensin blockade prevents the augmentation of intrarenal angiotensin II and podocyte abnormalities in type 2 diabetic rats with microalbuminuria.

scientific article published on September 2008

Successful therapy of Cushing's disease caused by an extrapituitary parasellar adenoma

scientific article published on 18 December 2009

Systemic candesartan reduces brain angiotensin II via downregulation of brain renin-angiotensin system

scientific article published on 27 November 2009

The Multidisciplinary Swallowing Team Approach Decreases Pneumonia Onset in Acute Stroke Patients

scientific article

The association between hyperintense vessel sign and final ischemic lesion differ in its location

scientific article published on 11 January 2014

The expression of CD36 in vessels with blood-brain barrier impairment in a stroke-prone hypertensive model

scientific article published on 01 December 2011

The expression of matrix metalloproteinase-13 is increased in vessels with blood-brain barrier impairment in a stroke-prone hypertensive model

scientific article published on 20 March 2009

The optimal timing of antihypertensive medication administration for morning hypertension in patients with cerebral infarction

scientific article published in March 2012

The prolactin regulatory element-binding regulates of the 11beta-hydroxylase gene.

scientific article published on 16 September 2008

The transcription factor prolactin regulatory element-binding protein mediates prolactin transcription induced by thyrotropin-releasing hormone in GH3 cells

scientific article published on 5 May 2010

The transcriptional factor prolactin regulatory element-binding protein mediates the gene transcription of adrenal scavenger receptor class B type I via 3',5'-cyclic adenosine 5'-monophosphate

scientific article

Therapeutic effects of postischemic treatment with hypotensive doses of an angiotensin II receptor blocker on transient focal cerebral ischemia

scientific article published in November 2011

Thrombin inhibition attenuates neurodegeneration and cerebral edema formation following transient forebrain ischemia

scientific article (publication date: June 2001)

Tissue Doppler echocardiography for predicting arterial stiffness assessed by cardio-ankle vascular index

scientific article published in February 2009

Tumor necrosis factor-alpha neutralization reduced cerebral edema through inhibition of matrix metalloproteinase production after transient focal cerebral ischemia

scientific article published in August 2005

Two cases of cerebral embolism caused by apical thrombi in midventricular obstructive cardiomyopathy

scientific article published on 01 May 2011

Ultrasonographic nerve enlargement of the median and ulnar nerves and the cervical nerve roots in patients with demyelinating Charcot-Marie-Tooth disease: distinction from patients with chronic inflammatory demyelinating polyneuropathy

scientific article published on 3 July 2013

Ultrasonographic reference sizes of the median and ulnar nerves and the cervical nerve roots in healthy Japanese adults

scientific article published on 03 July 2013

Usefulness of brain natriuretic peptide as a marker for separating cardiac and noncardiac causes of syncope

scientific article published in January 2004

Various meteorological conditions exhibit both immediate and delayed influences on the risk of stroke events: The HEWS-stroke study.

scientific article

Vascular proliferation and transforming growth factor-beta expression in pre- and early stage of diabetes mellitus in Otsuka Long-Evans Tokushima fatty rats

scientific article

Visit-to-visit variability in blood pressure over a 1-year period is a marker of left ventricular diastolic dysfunction in treated hypertensive patients

scientific article published on 12 May 2011

[Clinical characteristics of ischemic stroke in elderly patients with cancer]

scientific article published on 01 January 2011

c-Jun N-terminal kinases inhibitor suppresses the TNF-alpha induced MCP-1 expression in human umbilical vein endothelial cells.

scientific article

List of works by Naohisa Hosomi

17β-Estradiol regulates scavenger receptor class BI gene expression via protein kinase C in vascular endothelial cells.

A case of rheumatoid arthritis complicated by demyelination in both cerebral cortex and spinal cord during etanercept therapy

Abcb1a and Abcb1b expression in senescence-accelerated mouse (SAM).

Acute improvement of cardiac efficiency measured by 11C-acetate PET after cardiac resynchronization therapy and clinical outcome

Age-related changes in P-glycoprotein expression in senescence-accelerated mouse

Age-related decrease in inferior vena cava diameter measured with echocardiography

Alpha2-macroglobulin as a promising biomarker for cerebral small vessel disease in acute ischemic stroke patients.

Alteration in aortic wall stiffness and accumulation of collagen during the prediabetic stage of type II diabetes mellitus in rats

Analysis of association between brain natriuretic peptide levels and blood pressure variability

Angiotensin II induces human astrocyte senescence through reactive oxygen species production

Angiotensin type 1 receptor blockage improves ischemic injury following transient focal cerebral ischemia

Aortic annular velocity assessed by tissue Doppler echocardiography as a potential parameter of arterial stiffness

Association between arterial stiffness and pulmonary function in hypertensive patients

Association between bone mineral density and arterial stiffness in hypertensive patients

Association between echocardiographic parameters and brain natriuretic peptide levels in treated hypertensive patients

Association between high-sensitivity C-reactive protein and left ventricular diastolic function assessed by echocardiography in patients with cardiovascular risk factors

Association between left ventricular hypertrophy and changes in arterial stiffness during hypertensive treatment

Association between oxidative stress assessed by urinary 8-hydroxydeoxyguanosine and the cardiac function in hypertensive patients without overt heart disease

Association between stroke lesions and videofluoroscopic findings in acute stroke patients

Association of cardio-ankle vascular index with brain natriuretic peptide levels in hypertension

Association of plasma adrenomedullin with carotid atherosclerosis in chronic ischemic stroke

Association of serum anti-periodontal pathogen antibody with ischemic stroke

Augmentation of intrarenal angiotensin II levels in uninephrectomized aldosterone/salt-treated hypertensive rats; renoprotective effects of an ultrahigh dose of olmesartan

Axonal damage in acute cerebral infarction showing ADC reduction

Blood pressure variability and prognosis in acute ischemic stroke with vascular compression on the rostral ventrolateral medulla (RVLM)

Brain natriuretic peptide as a surrogate marker for cardioembolic stroke with paroxysmal atrial fibrillation

CD36 expression in the brains of SAMP8.

Cancer-associated ischemic stroke is associated with elevated D-dimer and fibrin degradation product levels in acute ischemic stroke with advanced cancer

Cardiac diastolic dysfunction is associated with cerebral white matter lesions in elderly patients with risk factors for atherosclerosis

Carotid turbulent flow observed by convergent color Doppler flowmetry in silent cerebral infarction

Cerebellar diaschisis in pontine infarctions: a report of five cases

Clinical significance of differences between home and clinic systolic blood pressure readings in patients with hypertension

Comparison of central blood pressure and cardio-ankle vascular index for association with cardiac function in treated hypertensive patients.

Comparison of magnetic resonance imaging and transesophageal echocardiography in detection of thrombus in the left atrial appendage

Correlation of arterial stiffness to left ventricular function in patients with reduced ejection fraction

Decline of plasma brain natriuretic peptide during enzyme replacement therapy in a female patient with heterozygous Fabry's disease

Differences in left ventricular hypertrophy and dysfunction between patients with cerebral hemorrhage and those with cerebral infarction

Differential effects of neonatal maternal separation on the expression of neurotrophic factors in rat brain. II: Regional differences in the cerebellum versus the cerebral cortex

Do RAS inhibitors protect the brain from cerebral ischemic injury?

Dural arteriovenous fistula presenting with progressive dementia and parkinsonism

Early detection of hypertension in a patient treated with sunitinib by measuring cardio-ankle vascular index.

Early postnatal maternal separation causes alterations in the expression of β3-adrenergic receptor in rat adipose tissue suggesting long-term influence on obesity

Echocardiographic assessment of the cardio-renal connection: is left ventricular hypertrophy or diastolic function more closely correlated with estimated glomerular filtration rate in patients with cardiovascular risk factors?

Effects of adrenomedullin on cardiac oxidative stress and collagen accumulation in aldosterone-dependent malignant hypertensive rats

Effects of pravastatin sodium and simvastatin on plasma fibrinogen level and blood rheology in type II hyperlipoproteinemia.

Effects of troglitazone on collagen accumulation and distensibility of aortic wall in prestage of non-insulin-dependent diabetes mellitus of Otsuka Long-Evans Tokushima Fatty rats.

Efficacy of anti-coagulant treatment with argatroban on cardioembolic stroke

Elevated brachial-ankle pulse wave velocity is associated with left ventricular hypertrophy in hypertensive patients after stroke

Genome-wide response to antihypertensive medication using home blood pressure measurements: a pilot study nested within the HOMED-BP study

Hyperglycemia suppresses ABCA1 expression in vascular smooth muscle cells

Increased blood pressure variability during the subacute phase of ischemic stroke is associated with poor functional outcomes at 3 months

Independent determinants of the Tei index in hypertensive patients with preserved left ventricular systolic function

Induced hypertension treatment to improve cerebral ischemic injury after transient forebrain ischemia

Influences of hypertension and diabetes on normal age-related changes in left ventricular function as assessed by tissue Doppler echocardiography

Inhibitory effects of a dihydropyridine calcium channel blocker on renal injury in aldosterone-infused rats

Involvement of mineralocorticoid receptor in high glucose-induced big mitogen-activated protein kinase 1 activation and mesangial cell proliferation

Isolated unilateral hypoglossal nerve paralysis caused by internal carotid artery dissection

Mechanical stretch augments insulin-induced vascular smooth muscle cell proliferation by insulin-like growth factor-1 receptor

Mechanical stretch potentiates angiotensin II-induced proliferation in spontaneously hypertensive rat vascular smooth muscle cells

Microglial cell activation is a source of metalloproteinase generation during hemorrhagic transformation.

Neonatal repetitive maternal separation causes long-lasting alterations in various neurotrophic factor expression in the cerebral cortex of rats

Plasma brain natriuretic peptide as a surrogate marker for cardioembolic stroke

Possible contribution of the non-proteolytic activation of prorenin to the development of insulin resistance in fructose-fed rats.

Possible involvement of Rho-kinase in aldosterone-induced vascular smooth muscle cell remodeling

Predictors of intracerebral hemorrhage severity and its outcome in Japanese stroke patients

Prorenin induces vascular smooth muscle cell proliferation and hypertrophy via epidermal growth factor receptor-mediated extracellular signal-regulated kinase and Akt activation pathway

RAGE, LDL receptor, and LRP1 expression in the brains of SAMP8.

Rationale, design, and baseline features of a randomized controlled trial to assess the effects of statin for the secondary prevention of stroke: the Japan Statin Treatment Against Recurrent Stroke (J-STARS)

Reduced bone mineral density in hypertensive patients is associated with left ventricular diastolic dysfunction, not left ventricular hypertrophy

Relation of postischemic delayed hypoperfusion and cerebral edema after transient forebrain ischemia

Relationship between arterial stiffness and variability in systolic blood pressure during a single clinic visit in patients with hypertension

Renin-angiotensin system in neuronal disease

Reversible magnetic resonance imaging changes associated with hypoglycemia. Case report

Safety evaluation of substituting clopidogrel for ticlopidine in Japanese patients with ischemic stroke--Hiroshima ticlopidine, clopidogrel safe exchange trial

Short-term ethanol exposure causes imbalanced neurotrophic factor allocation in the basal forebrain cholinergic system: a novel insight into understanding the initial processes of alcohol addiction

Short-term exposure to ethanol causes a differential response between nerve growth factor and brain-derived neurotrophic factor ligand/receptor systems in the mouse cerebellum

Smoking, fasting serum insulin, and obesity are the predictors of carotid atherosclerosis in relatively young subjects

Strict angiotensin blockade prevents the augmentation of intrarenal angiotensin II and podocyte abnormalities in type 2 diabetic rats with microalbuminuria.

Successful therapy of Cushing's disease caused by an extrapituitary parasellar adenoma