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List of works by Hiroshi Iwakura

A link between FTO, ghrelin, and impaired brain food-cue responsivity

scientific article

A postweaning reduction in circulating ghrelin temporarily alters growth hormone (GH) responsiveness to GH-releasing hormone in male mice but does not affect somatic growth

scientific article

Adrenal tumor volume in a genetically engineered mouse model of neuroblastoma determined by magnetic resonance imaging

scientific article (publication date: July 2012)

Analysis of plasma ghrelin in patients with medium-chain acyl-CoA dehydrogenase deficiency and glutaric aciduria type II

scientific article published on 02 November 2011

Analysis of rat insulin II promoter-ghrelin transgenic mice and rat glucagon promoter-ghrelin transgenic mice.

scientific article published on 8 February 2005

CRISPR/Cas9-mediated Angptl8 knockout suppresses plasma triglyceride concentrations and adiposity in rats

scientific article published on 24 July 2018

Clinical effects of ghrelin on gastrointestinal involvement in patients with systemic sclerosis.

scientific article published on 17 May 2014

Comprehensive Profiling of GPCR Expression in Ghrelin-Producing Cells.

scientific article published on 15 December 2015

Differential role of GPR142 in tryptophan-mediated enhancement of insulin secretion in obese and lean mice.

scientific article published on 11 June 2018

Effects of ghrelin administration on decreased growth hormone status in obese animals

scientific article published on 26 June 2007

Effects of ghrelin treatment on patients undergoing total hip replacement for osteoarthritis: different outcomes from studies in patients with cardiac and pulmonary cachexia.

scientific article

Efficacy of ghrelin as a therapeutic approach for age-related physiological changes

scientific article published on 27 March 2008

Endogenous peptide profile for elucidating biosynthetic processing of the ghrelin precursor.

scientific article

Establishment of Leptin-Responsive Cell Lines from Adult Mouse Hypothalamus

scientific article

Establishment of a novel ghrelin-producing cell line.

scientific article published on 7 April 2010

GPR40 gene expression in human pancreas and insulinoma.

scientific article

Generation of transgenic mice overexpressing a ghrelin analog

scientific article published on 20 October 2010

Genetic and pharmacological inhibition of Rho-associated kinase II enhances adipogenesis.

scientific article published on 6 August 2007

Ghrelin expression in islet cell tumors: augmented expression of ghrelin in a case of glucagonoma with multiple endocrine neoplasm type I.

scientific article published in November 2002

Ghrelin prevents development of diabetes at adult age in streptozotocin-treated newborn rats

scientific article

Ghrelin strongly stimulates growth hormone release in humans

scientific article published on 01 December 2000

Graves' Disease in Pediatric and Elderly Patients with 22q11.2 Deletion Syndrome.

scientific article

High incorporation of long-chain fatty acids contributes to the efficient production of acylated ghrelin in ghrelin-producing cells.

scientific article published on 14 March 2016

IL-1β directly suppress ghrelin mRNA expression in ghrelin-producing cells.

scientific article published on 22 February 2017

Lacto-ghrestatin, a novel bovine milk-derived peptide, suppresses ghrelin secretion

scientific article published on 26 June 2017

Notch/Rbp-j signaling prevents premature endocrine and ductal cell differentiation in the pancreas

scientific article published on 01 January 2006

Nutrients differentially regulate nucleobindin-2/nesfatin-1 in vitro in cultured stomach ghrelinoma (MGN3-1) cells and in vivo in male mice.

scientific article

Overexpression of intraislet ghrelin enhances β-cell proliferation after streptozotocin-induced β-cell injury in mice

scientific article published on 7 May 2013

Oxytocin and Dopamine Stimulate Ghrelin Secretion by the Ghrelin-Producing Cell Line, MGN3-1 in Vitro ⬇️

scientific article published on April 26, 2011

Plasma ghrelin levels in healthy elderly volunteers: the levels of acylated ghrelin in elderly females correlate positively with serum IGF-I levels and bowel movement frequency and negatively with systolic blood pressure.

scientific article

Rbp-j regulates expansion of pancreatic epithelial cells and their differentiation into exocrine cells during mouse development

scientific article published on 01 October 2007

Reduction in circulating ghrelin concentration after maturation does not affect food intake

scientific article published on 17 July 2014

Repeated administration of ghrelin to patients with functional dyspepsia: its effects on food intake and appetite.

scientific article published in April 2008

Sensing of Fatty Acids for Octanoylation of Ghrelin Involves a Gustatory G-Protein ⬇️

scientific article published on June 29, 2012

Soy-ghretropin, a novel ghrelin-releasing peptide derived from soy protein

scientific article published on 15 July 2016

Transgenic mice overexpressing des-acyl ghrelin show small phenotype

scientific article published on 7 October 2004

Transgenic mice overexpressing ghrelin or ghrelin analog

scientific article published on 01 January 2012

Transgenic overexpression of intraislet ghrelin does not affect insulin secretion or glucose metabolism in vivo

scientific article published on 22 November 2011

Up-regulation of uncoupling protein 3 gene expression by fatty acids and agonists for PPARs in L6 myotubes.

scientific article

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