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List of works by James L Trevaskis

A GLP-1:CCK fusion peptide harnesses the synergistic effects on metabolism of CCK-1 and GLP-1 receptor agonism in mice

scientific article published on 19 May 2018

A Life without Hunger: The Ups (and Downs) to Modulating Melanocortin-3 Receptor Signaling.

scientific article published on 16 March 2017

Amylin-mediated restoration of leptin responsiveness in diet-induced obesity: magnitude and mechanisms

scientific article published on 31 July 2008

Amylin/leptin synergy is absent in extreme obesity and not restored by calorie restriction-induced weight loss in rats

scientific article published on 07 September 2016

Antiobesity effects of the beta-cell hormone amylin in combination with phentermine or sibutramine in diet-induced obese rats

scientific article published on 17 June 2008

Bifunctional PEGylated exenatide-amylinomimetic hybrids to treat metabolic disorders: an example of long-acting dual hormonal therapeutics

scientific article

Calpain 3 gene expression in skeletal muscle is associated with body fat content and measures of insulin resistance

scientific article published on 01 April 2002

Counterintuitive effects of double-heterozygous null melanocortin-4 receptor and leptin genes on diet-induced obesity and insulin resistance in C57BL/6J mice

scientific article

Davalintide (AC2307), a novel amylin-mimetic peptide: enhanced pharmacological properties over native amylin to reduce food intake and body weight

scientific article published on 24 November 2009

Diet-genotype interactions in the development of the obese, insulin-resistant phenotype of C57BL/6J mice lacking melanocortin-3 or -4 receptors.

scientific article published on 09 February 2006

Differential Effects of a Glucagon-Like Peptide 1 Receptor Agonist in Non-Alcoholic Fatty Liver Disease and in Response to Hepatectomy

scientific article published in Scientific Reports

Effects of prior or concurrent food restriction on amylin-induced changes in body weight and body composition in high-fat-fed female rats

scientific article published on 14 August 2007

Engineering of a GLP-1 analogue peptide/anti-PCSK9 antibody fusion for type 2 diabetes treatment

scientific article published in Scientific Reports

Enhanced amylin-mediated body weight loss in estradiol-deficient diet-induced obese rats

scientific article published on 20 October 2010

Essential Role for Hypothalamic Calcitonin Receptor‒Expressing Neurons in the Control of Food Intake by Leptin

scientific article published on 7 March 2018

Genetic variation in SH3-domain GRB2-like (endophilin)-interacting protein 1 has a major impact on fat mass

scientific article

Glucagon-like peptide-1 receptor agonism improves metabolic, biochemical, and histopathological indices of nonalcoholic steatohepatitis in mice ⬇️

scientific article published on January 19, 2012

Gut check on diabesity: leveraging gut mechanisms for the treatment of type 2 diabetes and obesity

scientific article published on 10 August 2017

Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism.

scientific article published on December 2008

Identification of hypothalamic genes implicated in the development of obesity in Psammomys obesus using differential display PCR.

scientific article

Improved glucose control and reduced body weight in rodents with dual mechanism of action peptide hybrids.

scientific article

Interaction of leptin and amylin in the long-term maintenance of weight loss in diet-induced obese rats.

scientific article published on 18 June 2009

Interactions of amylinergic and melanocortinergic systems in the control of food intake and body weight in rodents

scientific article published on 20 February 2012

Leptin responsiveness restored by amylin agonism in diet-induced obesity: evidence from nonclinical and clinical studies

scientific article

Localization and expression of selenoprotein S in the testis of Psammomys obesus

scientific article published on 16 December 2006

Mechanisms of amylin/leptin synergy in rodent models

scientific article published on 29 October 2009

Melanocortin signaling in the CNS directly regulates circulating cholesterol

scientific article

Multi-hormonal weight loss combinations in diet-induced obese rats: therapeutic potential of cholecystokinin?

scientific article published on 3 March 2010

Neurturin and a GLP-1 Analogue Act Synergistically to Alleviate Diabetes in Zucker Diabetic Fatty Rats

scientific article

Pancreatic β-Cell Rest Replenishes Insulin Secretory Capacity and Attenuates Diabetes in an Extreme Model of Obese Type 2 Diabetes

article

Rapid development of non-alcoholic steatohepatitis in Psammomys obesus (Israeli sand rat)

scientific article

Robust anti-obesity and metabolic effects of a dual GLP-1/glucagon receptor peptide agonist in rodents and non-human primates

scientific article

Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1, a novel neuronal protein that regulates energy balance

scientific article

Superior reductions in hepatic steatosis and fibrosis with co-administration of a glucagon-like peptide-1 receptor agonist and obeticholic acid in mice

scientific article published on 14 September 2017

Synergistic metabolic benefits of an exenatide analogue and cholecystokinin in diet-induced obese and leptin-deficient rodents

scientific article published on 14 October 2014

Tanis: a link between type 2 diabetes and inflammation?

scientific article

The PYY/Y2R-Deficient Mouse Responds Normally to High-Fat Diet and Gastric Bypass Surgery

scientific article published on 10 March 2019

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