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List of works by Michael A. Freitas

A mass accuracy sensitive probability based scoring algorithm for database searching of tandem mass spectrometry data

scientific article

A multi-model statistical approach for proteomic spectral count quantitation

scientific article published on 31 May 2016

A quantitative proteomic workflow for characterization of frozen clinical biopsies: laser capture microdissection coupled with label-free mass spectrometry

scientific article

A robust linear regression based algorithm for automated evaluation of peptide identifications from shotgun proteomics by use of reversed-phase liquid chromatography retention time

scientific article

Age-related changes in mesenchymal stem cells derived from rhesus macaque bone marrow.

scientific article

Alterations of Histone H1 Phosphorylation During Bladder Carcinogenesis ⬇️

scientific article published on June 17, 2013

Apigenin induces DNA damage through the PKCδ-dependent activation of ATM and H2AX causing down-regulation of genes involved in cell cycle control and DNA repair.

scientific article

Application of mass spectrometry to the identification and quantification of histone post-translational modifications.

scientific article published on July 2004

Assaying pharmacodynamic endpoints with targeted therapy: flavopiridol and 17AAG induced dephosphorylation of histone H1.5 in acute myeloid leukemia

scientific article

Automated diagnosis of LC-MS/MS performance.

scientific article published on 20 March 2009

Characterization of glomerular diseases using proteomic analysis of laser capture microdissected glomeruli.

scientific article

Characterization of multiple myeloma vesicles by label-free relative quantitation.

scientific article published on October 2013

Citrate is a major component of snake venoms

scientific article published on 01 April 1992

Correction: In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation

scientific article

Database search algorithm for identification of intact cross-links in proteins and peptides using tandem mass spectrometry.

scientific article

Differential expression of histone post-translational modifications in acute myeloid and chronic lymphocytic leukemia determined by high-pressure liquid chromatography and mass spectrometry

scientific article published on January 2004

Discovery of histone modification crosstalk networks by stable isotope labeling of amino acids in cell culture mass spectrometry (SILAC MS)

scientific article

Gas phase RNA and DNA ions 2. Conformational dependence of the gas-phase H/D exchange of nucleotide-5'-monophosphates

scientific article published in July 2001

Gas-phase hydrogen/deuterium exchange of positively charged mononucleotides by use of Fourier-transform ion cyclotron resonance mass spectrometry

scientific article

Gas-phase reactions of glycine, alanine, valine and their N-methyl derivatives with the nitrosonium ion, NO+

scientific article published on 01 October 1996

High-resolution Fourier transform ion cyclotron resonance mass spectrometry of humic and fulvic acids: improvements and comparisons.

scientific article

High‐sensitivity TFA‐free LC‐MS for profiling histones ⬇️

scientific article published on August 1, 2011

Histone H1 phosphorylation in breast cancer

scientific article

Histone H3-K56 acetylation is catalyzed by histone chaperone-dependent complexes

scientific article published on 22 February 2007

Histone H4 acetylation dynamics determined by stable isotope labeling with amino acids in cell culture and mass spectrometry

scientific article

Histone H4 lysine 91 acetylation a core domain modification associated with chromatin assembly

scientific article

Identification and characterization of disulfide bonds in proteins and peptides from tandem MS data by use of the MassMatrix MS/MS search engine

scientific article

Identification of histone demethylases in Saccharomyces cerevisiae.

scientific article

Identification of novel histone post-translational modifications by peptide mass fingerprinting

scientific article published on 9 July 2003

Identification of replication-dependent and replication-independent linker histone complexes: Tpr specifically promotes replication-dependent linker histone stability

scientific article

In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation

scientific article published on 22 April 2013

Increasing the complexity of chromatin: functionally distinct roles for replication-dependent histone H2A isoforms in cell proliferation and carcinogenesis ⬇️

scientific article published on August 16, 2013

Liquid chromatography mass spectrometry profiling of histones

scientific article published on 07 January 2007

Mass spectrometry-based strategies for characterization of histones and their post-translational modifications.

scientific article published on April 2007

MassMatrix: a database search program for rapid characterization of proteins and peptides from tandem mass spectrometry data

scientific article

Methylation of the PTPRO gene in human hepatocellular carcinoma and identification of VCP as its substrate ⬇️

scientific article published on August 1, 2013

MicroRNA regulation of stem cell differentiation and diseases of the bone and adipose tissue: Perspectives on miRNA biogenesis and cellular transcriptome

scientific article published on 26 February 2015

Monte carlo simulation-based algorithms for analysis of shotgun proteomic data

scientific article

Peptide-based inhibition of NF-κB rescues diaphragm muscle contractile dysfunction in a murine model of Duchenne muscular dystrophy.

scientific article

Proteomic Signatures of Thymomas

scientific article

Proteomic analysis reveals new cardiac-specific dystrophin-associated proteins

scientific article

Proteomic characterization of circulating extracellular vesicles identifies novel serum myeloma associated markers

scientific article published on 13 January 2016

Proteomic profiling identifies specific histone species associated with leukemic and cancer cells

scientific article

Quantitative Mass Spectrometry Reveals that Intact Histone H1 Phosphorylations are Variant Specific and Exhibit Single Molecule Hierarchical Dependence

scientific article published on 24 July 2015

SILAC peptide ratio calculator: a tool for SILAC quantitation of peptides and post-translational modifications.

scientific article published on 09 January 2014

Screening combinatorial libraries by mass spectrometry. 2. Identification of optimal substrates of protein tyrosine phosphatase SHP-1.

scientific article

Screening combinatorial libraries for optimal enzyme substrates by mass spectrometry

scientific article published in January 2001

Self-chemical ionization of diethylzinc

scientific article published on 01 January 1999

Simultaneous metabolic labeling of cells with multiple amino acids: Localization and dynamics of histone acetylation and methylation

scientific article published on 01 January 2007

Sites of acetylation on newly synthesized histone H4 are required for chromatin assembly and DNA damage response signaling.

scientific article published on 17 June 2013

Specificity profiling of dual specificity phosphatase vaccinia VH1-related (VHR) reveals two distinct substrate binding modes

scientific article

Tag-Count Analysis of Large-Scale Proteomic Data.

scientific article

Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL) ⬇️

scientific article published on January 30, 2012

Tetraspanin CD37 directly mediates transduction of survival and apoptotic signals

scientific article

The chromatin scaffold protein SAFB1 localizes SUMO-1 to the promoters of ribosomal protein genes to facilitate transcription initiation and splicing.

scientific article

The impact of cruciferous vegetable isothiocyanates on histone acetylation and histone phosphorylation in bladder cancer

scientific article published on 26 January 2017

The non-canonical hydroxylase structure of YfcM reveals a metal ion-coordination motif required for EF-P hydroxylation

scientific article

The novel deacetylase inhibitor AR-42 demonstrates pre-clinical activity in B-cell malignancies in vitro and in vivo

scientific article (publication date: 3 June 2010)

The potential diagnostic power of extracellular vesicle analysis for multiple myeloma.

scientific article published on 15 December 2015

Tool command language automation of the modular ion cyclotron data acquisition system (MIDAS) for data-dependent tandem Fourier transform ion cyclotron resonance mass spectrometry.

scientific article

Validation of an LC-MS based approach for profiling histones in chronic lymphocytic leukemia

scientific article

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