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List of works by Mimoun Azzouz

<i>C9ORF72</i>-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons

scientific article published on 13 May 2022

AAV9-mediated central nervous system-targeted gene delivery via cisterna magna route in mice

scientific article published on 17 February 2016

C9ORF72 hexanucleotide repeat exerts toxicity in a stable, inducible motor neuronal cell model, which is rescued by partial depletion of Pten

scientific article

C9orf72 expansion disrupts ATM-mediated chromosomal break repair.

scientific article

Comparison of stimulus-evoked cerebral hemodynamics in the awake mouse and under a novel anesthetic regime

scientific article published on 28 July 2015

Corrigendum: Comparison of stimulus-evoked cerebral hemodynamics in the awake mouse and under a novel anesthetic regime.

scientific article published on 8 October 2015

Current developments in gene therapy for amyotrophic lateral sclerosis

scientific article published on 10 May 2015

Deficiency in the mRNA export mediator Gle1 impairs Schwann cell development in the zebrafish embryo

scientific article published on 24 February 2016

Development and applications of non-HIV-based lentiviral vectors in neurological disorders

scientific article published in December 2008

Development of Nonviral Vectors Targeting the Brain as a Therapeutic Approach For Parkinson's Disease and Other Brain Disorders.

scientific article published on 24 December 2015

Dopamine gene therapy for Parkinson's disease in a nonhuman primate without associated dyskinesia.

scientific article published in October 2009

Early detection of motor dysfunction in the SOD1G93A mouse model of Amyotrophic Lateral Sclerosis (ALS) using home cage running wheels

scientific article

Electromyographical and Motor Performance Studies in thepmnMouse Model of Neurodegenerative Disease

scientific article published in April 1996

Encapsulation of biomacromolecules within polymersomes by electroporation.

scientific article

Enhancement of Mouse Sciatic Nerve Regeneration by the Long Chain Fatty Alcohol,N-Hexacosanol

scientific article published in April 1996

Gene Therapy for ALS: progress and prospects

scientific article published on 22 May 2006

Gene Therapy in the Nervous System: Failures and Successes.

scientific article

Gene therapy for neurodegenerative and ocular diseases using lentiviral vectors

scientific article

Gene therapy: a promising approach to treating spinal muscular atrophy.

scientific article published on 27 June 2014

LRP-1-mediated intracellular antibody delivery to the Central Nervous System

scientific article published on 20 July 2015

Lentivector-mediated delivery of GDNF protects complex motor functions relevant to human Parkinsonism in a rat lesion model.

scientific article published on November 2005

Lentiviral vectors for the treatment of neurodegenerative diseases

scientific article published on October 1, 2001

Lentiviral vectors for treating and modeling human CNS disorders

scientific article published in September 2004

Local GDNF expression mediated by lentiviral vector protects facial nerve motoneurons but not spinal motoneurons in SOD1(G93A) transgenic mice

scientific article published on June 2004

Meta-Analysis of Autoimmune Regulator-Regulated Genes in Human and Murine Models: A Novel Human Model Provides Insights on the Role of Autoimmune Regulator in Regulating STAT1 and STAT1-Regulated Genes.

scientific article published on 28 June 2018

Optimised and rapid pre-clinical screening in the SOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis (ALS).

scientific article

PTEN depletion decreases disease severity and modestly prolongs survival in a mouse model of spinal muscular atrophy

scientific article

PTEN depletion rescues axonal growth defect and improves survival in SMN-deficient motor neurons

scientific article published on 4 June 2010

PTEN regulates AMPA receptor-mediated cell viability in iPS-derived motor neurons.

scientific article published on 27 February 2014

Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis

scientific article

Plastin 3 Promotes Motor Neuron Axonal Growth and Extends Survival in a Mouse Model of Spinal Muscular Atrophy.

scientific article

Prevention of mutant SOD1 motoneuron degeneration by copper chelatorsin vitro

scientific article published in January 2000

Progressive motor neuron impairment in an animal model of familial amyotrophic lateral sclerosis

scientific article published in January 1997

Retinoic acid receptor beta2 promotes functional regeneration of sensory axons in the spinal cord

scientific article published on 25 December 2005

SMN-deficient cells exhibit increased ribosomal DNA damage

scientific article published on 19 April 2022

SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits

scientific article

Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model

scientific article

Site Specific Modification of Adeno-Associated Virus Enables Both Fluorescent Imaging of Viral Particles and Characterization of the Capsid Interactome.

scientific article published on 7 November 2017

Systemic delivery of scAAV9 expressing SMN prolongs survival in a model of spinal muscular atrophy

scientific article published in June 2010

The AIRE -230Y Polymorphism Affects AIRE Transcriptional Activity: Potential Influence on AIRE Function in the Thymus

scientific article

Therapeutic gene silencing in neurological disorders, using interfering RNA.

scientific article

Transduction Patterns of Pseudotyped Lentiviral Vectors in the Nervous System

scientific article published in January 2004

Translating SOD1 Gene Silencing toward the Clinic: A Highly Efficacious, Off-Target-free, and Biomarker-Supported Strategy for fALS.

scientific article

Trophic activity of Rabies G protein-pseudotyped equine infectious anemia viral vector mediated IGF-I motor neuron gene transfer in vitro

scientific article published in December 2005

VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model

scientific article published in May 2004

Viral delivery of C9orf72 hexanucleotide repeat expansions in mice leads to repeat-length-dependent neuropathology and behavioural deficits

scientific article published on 26 May 2017

Viral delivery of antioxidant genes as a therapeutic strategy in experimental models of amyotrophic lateral sclerosis

scientific article

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