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List of works by Agueda Gonzalez-rodriguez

Azathioprine desensitizes liver cancer cells to insulin-like growth factor 1 and causes apoptosis when it is combined with bafilomycin A1.

scientific article published on 16 August 2013

Beneficial effects of PTP1B deficiency on brown adipocyte differentiation and protection against apoptosis induced by pro- and anti-inflammatory stimuli.

scientific article

Beneficial effects of fenofibrate in retinal pigment epithelium by the modulation of stress and survival signaling under diabetic conditions.

scientific article

CHOP is a critical regulator of acetaminophen-induced hepatotoxicity.

scientific article published on 9 May 2013

Differential insulin receptor substrate-1 (IRS1)-related modulation of neuropeptide Y and proopiomelanocortin expression in nondiabetic and diabetic IRS2-/- mice

scientific article

Essential role of protein tyrosine phosphatase 1B in obesity‐induced inflammation and peripheral insulin resistance during aging ⬇️

scientific article published on February 1, 2012

Essential role of protein-tyrosine phosphatase 1B in the modulation of insulin signaling by acetaminophen in hepatocytes

scientific article published on 9 September 2014

Eukaryotic elongation factor 2 controls TNF-α translation in LPS-induced hepatitis.

scientific article published in April 2014

Hepatic cyclooxygenase-2 expression protects against diet-induced steatosis, obesity, and insulin resistance.

scientific article published on 24 November 2014

Hepatic insulin resistance is associated with increased apoptosis and fibrogenesis in nonalcoholic steatohepatitis and chronic hepatitis C.

scientific article published on 27 August 2010

IL-6 cooperates with peroxisome proliferator-activated receptor-α-ligands to induce liver fatty acid binding protein (LFABP) up-regulation.

scientific article published on 28 March 2013

IRS2 and PTP1B: Two opposite modulators of hepatic insulin signalling.

scientific article published on 14 March 2011

Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD.

scientific article published on 17 April 2014

Impairment of transforming growth factor beta signaling in caveolin-1-deficient hepatocytes: role in liver regeneration.

scientific article

In vivo siRNA delivery of Keap1 modulates death and survival signaling pathways and attenuates concanavalin-A-induced acute liver injury in mice.

scientific article published on 4 July 2014

Increased oxidative stress and apoptosis in the hypothalamus of diabetic male mice in the insulin receptor substrate-2 knockout model.

scientific article published on 24 March 2016

Insulin receptor substrate 2 (IRS2)-deficient mice show sensorineural hearing loss that is delayed by concomitant protein tyrosine phosphatase 1B (PTP1B) loss of function

scientific article

Liver-specific insulin receptor isoform A expression enhances hepatic glucose uptake and ameliorates liver steatosis in a mouse model of diet-induced obesity

scientific article published on 07 February 2019

Loss of protein tyrosine phosphatase 1B increases IGF-I receptor tyrosine phosphorylation but does not rescue retinal defects in IRS2-deficient mice

scientific article published on 19 June 2013

Normal proliferation and tumorigenesis but impaired pancreatic function in mice lacking the cell cycle regulator sei1.

scientific article

PTP1B deficiency enhances liver growth during suckling by increasing the expression of insulin-like growth factor-I.

scientific article published in October 2010

PTP1B deficiency increases glucose uptake in neonatal hepatocytes: involvement of IRA/GLUT2 complexes.

scientific article published on 5 June 2008

Pivotal role of protein tyrosine phosphatase 1B (PTP1B) in the macrophage response to pro-inflammatory and anti-inflammatory challenge

scientific article published on 13 March 2014

Protein Tyrosine Phosphatase 1B (PTP1B) deficiency accelerates hepatic regeneration in mice

scientific article

Protein tyrosine phosphatase 1B modulates GSK3β/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity.

scientific article published on 9 May 2013

Protein-tyrosine phosphatase 1B (PTP1B) deficiency confers resistance to transforming growth factor-β (TGF-β)-induced suppressor effects in hepatocytes

scientific article

Studies of naturally occurring friedelane triterpenoids as insulin sensitizers in the treatment type 2 diabetes mellitus.

scientific article published on 25 August 2012

Topical administration of somatostatin prevents retinal neurodegeneration in experimental diabetes.

scientific article published on 8 March 2013

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