Search filters

List of works by Philip Hogg

A phase 1 trial of intravenous 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) in patients with advanced solid tumours

scientific article

A substrate-driven allosteric switch that enhances PDI catalytic activity

scientific article

Allosteric control of βII-tryptase by a redox active disulfide bond

scientific article published on 18 October 2013

Allosteric disulfides: Sophisticated molecular structures enabling flexible protein regulation

scientific article published on 10 January 2019

Alterations in the mitochondrial responses to PENAO as a mechanism of resistance in ovarian cancer cells.

scientific article published on 14 June 2015

An alternate covalent form of platelet αIIbβ3 integrin that resides in focal adhesions and has altered function

scientific article published on 01 October 2021

Analysis of disulfide bonds in protein structures

scientific article published on 30 April 2010

Autoregulation of von Willebrand factor function by a disulfide bond switch.

scientific article published on 28 February 2018

Biodistribution and imaging of an hsp90 ligand labelled with 111In and 67Ga for imaging of cell death

scientific article published on 20 January 2020

Characterization of a reduced form of plasma plasminogen as the precursor for angiostatin formation

scientific article published on 12 December 2013

Classification of Protein Disulphide Bonds

scientific article published on 01 January 2019

Contribution of allosteric disulfide bonds to regulation of hemostasis.

scientific article published on July 2009

Control of blood proteins by functional disulfide bonds.

scientific article published on 12 February 2014

Disulfide bond acquisition through eukaryotic protein evolution.

scientific article

Dual targeting of mitochondrial function and mTOR pathway as a therapeutic strategy for diffuse intrinsic pontine glioma

scientific article published on 8 January 2018

Dual-targeting of aberrant glucose metabolism in glioblastoma

scientific article

Elimination of the antimicrobial action of the organoarsenical cancer therapeutic, 4-(N-(S-glutathionylacetyl)amino) phenylarsonous acid, before finished product sterility testing

scientific article published on 18 September 2013

Employing pancreatic tumor γ-glutamyltransferase for therapeutic delivery

scientific article published on 2 April 2014

Encryption and decryption of tissue factor.

scientific article published on June 2013

Factor XI is a substrate for oxidoreductases: enhanced activation of reduced FXI and its role in antiphospholipid syndrome thrombosis

scientific article published on 13 June 2012

Fibrinogen function achieved through multiple covalent states

scientific article published on 29 October 2020

Global redox proteome and phosphoproteome analysis reveals redox switch in Akt

scientific article published on 02 December 2019

Hypoxia regulates the production and activity of glucose transporter-1 and indoleamine 2,3-dioxygenase in monocyte-derived endothelial-like cells: possible relevance to infantile haemangioma pathogenesis

scientific article published on 01 February 2011

Identification of allosteric disulfides from labile bonds in X-ray structures.

scientific article published on 7 February 2018

JMJD1C-mediated metabolic dysregulation contributes to HOXA9-dependent leukemogenesis

scientific article published on 08 January 2019

Lateral self-association of VWF involves the Cys2431-Cys2453 disulfide/dithiol in the C2 domain

Mechanism of dimerization of a recombinant mature vascular endothelial growth factor C

scientific article published on 26 December 2013

Mechano-redox control of integrin de-adhesion

scientific article published on 22 June 2018

Mitochondrial metabolism inhibitors for cancer therapy.

scientific article published on 15 September 2011

Multiple Disulfide-Bonded States of Native Proteins: Estimate of Number Using Probabilities of Disulfide Bond Formation

scientific article published on 04 December 2020

Necrotic platelets provide a procoagulant surface during thrombosis

scientific article

Novel assay demonstrates that coronary artery disease patients have heightened procoagulant platelet response.

scientific article published on 22 March 2018

One-Way Allosteric Communication between the Two Disulfide Bonds in Tissue Factor.

scientific article published in January 2017

Optical Imaging of Treatment-Related Tumor Cell Death Using a Heat Shock Protein-90 Alkylator ⬇️

scientific article published on September 10, 2013

Optical imaging of cell death in traumatic brain injury using a heat shock protein-90 alkylator

scientific article published on 24 January 2013

Organic arsenicals as efficient and highly specific linkers for protein/peptide-polymer conjugation.

scientific article

Pharmaceutical development of the novel arsenical based cancer therapeutic GSAO for Phase I clinical trial

scientific article published on 21 January 2012

Plasminogen is tethered with high affinity to the cell surface by the plasma protein, histidine-rich glycoprotein

scientific article

Platelet Protein Disulfide Isomerase Promotes Glycoprotein Ibα-Mediated Platelet-Neutrophil Interactions Under Thromboinflammatory Conditions

scientific article published on 01 March 2019

Post-translational control of protein function by disulfide bond cleavage.

scientific article published on 15 February 2013

Preparation of a Dithiol-Reactive Probe for PET Imaging of Cell Death

scientific article published on 01 January 2019

Protein disulfide isomerase cleaves allosteric disulfides in histidine-rich glycoprotein to regulate thrombosis

scientific article published in 2024

Protein disulfide isomerase regulation by nitric oxide maintains vascular quiescence and controls thrombus formation

scientific article published on 12 October 2018

Reactive oxygen species and p38 mitogen-activated protein kinase mediate tumor necrosis factor α-converting enzyme (TACE/ADAM-17) activation in primary human monocytes.

scientific article published on 24 August 2011

Redox properties of the tissue factor Cys186-Cys209 disulfide bond

scientific article published on 01 August 2011

Redox regulation of methionine aminopeptidase 2 activity

scientific article

Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2

scientific article published on 11 September 2020

Reprogramming of human fibroblasts into osteoblasts by insulin-like growth factor-binding protein 7

scientific article published on 06 January 2020

TMX1: a new vascular thiol isomerase

scientific article published on 01 January 2019

Targeting allosteric disulphide bonds in cancer ⬇️

scientific article published on May 10, 2013

Targeting of two aspects of metabolism in breast cancer treatment

scientific article

The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas

scientific article published on 07 January 2020

The tumour metabolism inhibitors GSAO and PENAO react with cysteines 57 and 257 of mitochondrial adenine nucleotide translocase.

scientific article

Thiol isomerase ERp57 targets and modulates the lectin pathway of complement activation

scientific article published on 22 January 2019

Tyrosine nitration moderates the peptidase activity of human methionyl aminopeptidase 2.

scientific article

Zinc is a potent and specific inhibitor of IFN-λ3 signalling.

scientific article

γ-Crystallin redox-detox in the lens

scientific article published in Journal of Biological Chemistry

Paulina is supported by:

About Paulina

Help