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List of works by Kirsi Ketola

234 Drugs with known pharmacological profiles, such as monensin, disulfiram and salinomycin, show cancer-selective inhibition of prostate cancer cell growth by increasing oxidative stress

scholarly article by Kirsi Ketola et al published June 2010 in EJC supplements

A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care

scientific article

Abstract 3189: Neuronal transcription factor BRN2 is an androgen suppressed driver of neuroendocrine differentiation in prostate cancer

Abstract 4106: Lyn kinase promotes metastasis through EMT in cancers

Abstract A62: Monensin-induced oxidative stress reduces prostate cancer cell motility and cancer stem cell markers

Abstract C91: Targeting enzalutamide resistance in prostate cancer

Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer

scientific article

Axon Guidance-Related Factor FLRT3 Regulates VEGF-Signaling and Endothelial Cell Function

scientific article published on 12 March 2019

BCOR-coupled H2A monoubiquitination represses a subset of androgen receptor target genes regulating prostate cancer proliferation

scientific article published on 10 January 2020

CD44s Assembles Hyaluronan Coat on Filopodia and Extracellular Vesicles and Induces Tumorigenicity of MKN74 Gastric Carcinoma Cells

scientific article published on 22 March 2019

Chemical biology drug sensitivity screen identifies sunitinib as synergistic agent with disulfiram in prostate cancer cells

scientific article

High-throughput RNAi screening for novel modulators of vimentin expression identifies MTHFD2 as a regulator of breast cancer cell migration and invasion

scientific article

High-throughput cell-based compound screen identifies pinosylvin methyl ether and tanshinone IIA as inhibitors of castration-resistant prostate cancer

scientific article published on March 2016

High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth

scientific article

Monensin Induced Oxidative Stress Reduces Prostate Cancer Cell Migration and Cancer Stem Cell Population

Monensin is a potent inducer of oxidative stress and inhibitor of androgen signaling leading to apoptosis in prostate cancer cells

scientific article published on December 2010

PME-1 protects extracellular signal-regulated kinase pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma

scientific article

Regulation of tumor cell plasticity by the androgen receptor in prostate cancer

scientific article

Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress

scientific article published on January 2012

Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse

scientific article published on 06 September 2021

Targeting Lyn regulates Snail family shuttling and inhibits metastasis

scientific article published on 13 March 2017

Targeting Prostate Cancer Subtype 1 by Forkhead Box M1 Pathway Inhibition

scientific article published on 12 September 2017

The Master Neural Transcription Factor BRN2 Is an Androgen Receptor-Suppressed Driver of Neuroendocrine Differentiation in Prostate Cancer.

scientific article

The Plasticity of Stem-Like States in Patient-Derived Tumor Xenografts

scholarly article published 2017

The β2-Adrenergic Receptor Is a Molecular Switch for Neuroendocrine Transdifferentiation of Prostate Cancer Cells

scientific article published on 08 August 2019

Using online game-based platforms to improve student performance and engagement in histology teaching

scientific article published on 22 July 2019

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