List of works by Marina Bolzoni

Bone marrow monocyte-/macrophage-derived activin A mediates the osteoclastogenic effect of IL-3 in multiple myeloma

scientific article published on 26 December 2013

Bone osteoblastic and mesenchymal stromal cells lack primarily tumoral features in multiple myeloma patients

scientific article published on 20 May 2010

Cutaneous localization in multiple myeloma in the context of bortezomib-based treatment: how do myeloma cells escape from the bone marrow to the skin?

scientific article published on 3 October 2016

Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target.

scientific article published on 6 June 2016

Distinct transcriptional profiles characterize bone microenvironment mesenchymal cells rather than osteoblasts in relationship with multiple myeloma bone disease.

scientific article published on 4 December 2009

Expression of CD38 in myeloma bone niche: A rational basis for the use of anti-CD38 immunotherapy to inhibit osteoclast formation

scientific article published on 16 May 2017

Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo

scientific article published on 17 June 2016

HOXB7 expression by myeloma cells regulates their pro-angiogenic properties in multiple myeloma patients.

scientific article published on 23 November 2010

Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction.

scientific article published on 24 January 2013

IL21R expressing CD14+CD16+ monocytes expand in multiple myeloma patients leading to increased osteoclasts.

scientific article

Immunomodulatory drugs lenalidomide and pomalidomide inhibit multiple myeloma-induced osteoclast formation and the RANKL/OPG ratio in the myeloma microenvironment targeting the expression of adhesion molecules

scientific article published on 23 November 2012

Increased osteocyte death in multiple myeloma patients: role in myeloma-induced osteoclast formation.

scientific article published on 6 January 2012

Low bone marrow oxygen tension and hypoxia-inducible factor-1α overexpression characterize patients with multiple myeloma: role on the transcriptional and proangiogenic profiles of CD138+ cells

scientific article published on 02 September 2010

Mechanism of Action of Bortezomib and the New Proteasome Inhibitors on Myeloma Cells and the Bone Microenvironment: Impact on Myeloma-Induced Alterations of Bone Remodeling

scientific article

Microvesicles released from multiple myeloma cells are equipped with ectoenzymes belonging to canonical and non-canonical adenosinergic pathways and produce adenosine from ATP and NAD

scientific article published on 07 May 2018

Myeloma cells inhibit non-canonical wnt co-receptor ror2 expression in human bone marrow osteoprogenitor cells: effect of wnt5a/ror2 pathway activation on the osteogenic differentiation impairment induced by myeloma cells.

scientific article

NAD⁺-Metabolizing Ectoenzymes in Remodeling Tumor-Host Interactions: The Human Myeloma Model

scientific article

Osteolytic lesions, cytogenetic features and bone marrow levels of cytokines and chemokines in multiple myeloma patients: Role of chemokine (C-C motif) ligand 20.

scientific article

Overexpression of HOXB7 and homeobox genes characterizes multiple myeloma patients lacking the major primary immunoglobulin heavy chain locus translocations

article

Possible targets to treat myeloma-related osteoclastogenesis.

scientific article published on 2 March 2018

Role of Osteocytes in Myeloma Bone Disease: Anti-sclerostin Antibody as New Therapeutic Strategy

scientific article published on 24 October 2018

The Proteasome Inhibitor Bortezomib Maintains Osteocyte Viability in Multiple Myeloma Patients by Reducing Both Apoptosis and Autophagy: A New Function for Proteasome Inhibitors

scientific article published on 9 November 2015

The anti-tumoral effect of lenalidomide is increased in vivo by hypoxia-inducible factor (HIF)-1α inhibition in myeloma cells.

scientific article published on 11 December 2015

The link between bone microenvironment and immune cells in multiple myeloma: Emerging role of CD38

scientific article published on 24 April 2018

The osteoblastic niche in the context of multiple myeloma

scientific article

The potential of inhibiting glutamine uptake as a therapeutic target for multiple myeloma

scientific article published on 18 January 2017

The proapoptotic effect of zoledronic acid is independent of either the bone microenvironment or the intrinsic resistance to bortezomib of myeloma cells and is enhanced by the combination with arsenic trioxide.

scientific article published on 25 October 2010

Unraveling the contribution of ectoenzymes to myeloma life and survival in the bone marrow niche.

scientific article

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