List of works - Sameh Soror

1H-Imidazole-2,5-Dicarboxamides as NS4A Peptidomimetics: Identification of a New Approach to Inhibit HCV-NS3 Protease

scientific article published on 21 March 2020

A cold-active esterase of Streptomyces coelicolor A3(2): from genome sequence to enzyme activity.

scientific article published in August 2007

A llama-derived gelsolin single-domain antibody blocks gelsolin-G-actin interaction

scientific article

A novel expression system for production of soluble prion proteins in E. coli

scientific article published on 10 January 2012

Combining in-situ proteolysis and microseed matrix screening to promote crystallization of PrPc-nanobody complexes

scientific article published on 01 May 2011

Crystallization and preliminary X-ray diffraction analysis of a specific VHH domain against mouse prion protein

scientific article published on 26 November 2010

Design, synthesis, assessment, and molecular docking of novel pyrrolopyrimidine (7-deazapurine) derivatives as non-nucleoside hepatitis C virus NS5B polymerase inhibitors

scientific article published on 28 March 2016

Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors

scientific article published on 21 July 2017

Elevated Expression of MiR-17 in Microglia of Alzheimer's Disease Patients Abrogates Autophagy-Mediated Amyloid-β Degradation

scientific article published on 27 July 2021

Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors

scientific article

Expression, purification, characterization, and solution nuclear magnetic resonance study of highly deuterated yeast cytochrome C peroxidase with enhanced solubility

scientific article

High-resolution structure of a papaya plant-defense barwin-like protein solved by in-house sulfur-SAD phasing

scientific article

Inflammasome Genes' Polymorphisms in Egyptian Chronic Hepatitis C Patients: Influence on Vulnerability to Infection and Response to Treatment

article

Ligand efficiency driven design of new inhibitors of Mycobacterium tuberculosis transcriptional repressor EthR using fragment growing, merging, and linking approaches

scientific article

Mining the genome sequence for novel enzyme activity: characterisation of an unusual member of the hormone-sensitive lipase family of esterases from the genome of Streptomyces coelicolor A3 (2).

scientific article published on 25 March 2009

Novel antiviral compounds against gastroenteric viral infections

scientific article published on 18 February 2015

Probing the N-terminal β-sheet conversion in the crystal structure of the human prion protein bound to a nanobody

scientific article

Revealing the Potential Application of EC-Synthetic Retinoid Analogues in Anticancer Therapy

scientific article published on 19 January 2021

Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands

scientific article

Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion

scientific article published on 09 December 2019

List of works by Sameh Soror

1H-Imidazole-2,5-Dicarboxamides as NS4A Peptidomimetics: Identification of a New Approach to Inhibit HCV-NS3 Protease

A cold-active esterase of Streptomyces coelicolor A3(2): from genome sequence to enzyme activity.

A llama-derived gelsolin single-domain antibody blocks gelsolin-G-actin interaction

A novel expression system for production of soluble prion proteins in E. coli

Combining in-situ proteolysis and microseed matrix screening to promote crystallization of PrPc-nanobody complexes

Crystallization and preliminary X-ray diffraction analysis of a specific VHH domain against mouse prion protein

Design, synthesis, assessment, and molecular docking of novel pyrrolopyrimidine (7-deazapurine) derivatives as non-nucleoside hepatitis C virus NS5B polymerase inhibitors

Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors

Elevated Expression of MiR-17 in Microglia of Alzheimer's Disease Patients Abrogates Autophagy-Mediated Amyloid-β Degradation

Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors

Expression, purification, characterization, and solution nuclear magnetic resonance study of highly deuterated yeast cytochrome C peroxidase with enhanced solubility

High-resolution structure of a papaya plant-defense barwin-like protein solved by in-house sulfur-SAD phasing

Inflammasome Genes' Polymorphisms in Egyptian Chronic Hepatitis C Patients: Influence on Vulnerability to Infection and Response to Treatment

Ligand efficiency driven design of new inhibitors of Mycobacterium tuberculosis transcriptional repressor EthR using fragment growing, merging, and linking approaches

Mining the genome sequence for novel enzyme activity: characterisation of an unusual member of the hormone-sensitive lipase family of esterases from the genome of Streptomyces coelicolor A3 (2).

Novel antiviral compounds against gastroenteric viral infections

Probing the N-terminal β-sheet conversion in the crystal structure of the human prion protein bound to a nanobody

Revealing the Potential Application of EC-Synthetic Retinoid Analogues in Anticancer Therapy

Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands

Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion