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List of works by Richard Meehan

5-hydroxymethylcytosine profiling as an indicator of cellular state

scientific article published on December 2013

A component of the transcriptional repressor MeCP1 shares a motif with DNA methyltransferase and HRX proteins

scientific article (publication date: July 1997)

A gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of Syk

scientific article

A mutant form of MeCP2 protein associated with human Rett syndrome cannot be displaced from methylated DNA by notch in Xenopus embryos

retracted scientific article

A reassessment of DNA-immunoprecipitation-based genomic profiling

scientific article published on 25 June 2018

An in vitro model that recapitulates the epithelial to mesenchymal transition (EMT) in human breast cancer

scientific article

An unbalanced maternal diet in pregnancy associates with offspring epigenetic changes in genes controlling glucocorticoid action and foetal growth

scientific article

Apoptosis and DNA methylation.

scientific article published on April 2011

Binding of histone H1 to DNA is indifferent to methylation at CpG sequences

scientific article published in November 1995

Cloning and developmental expression of MARK/Par-1/MELK-related protein kinase xMAK-V in Xenopus laevis

scientific article published on 23 January 2004

Cloning and expression of sheep DNA methyltransferase 1 and its development-specific isoform

scientific article

Comparative analysis of affinity-based 5-hydroxymethylation enrichment techniques

scientific article

DNA methylation at promoter regions regulates the timing of gene activation in Xenopus laevis embryos

scientific article published in March 2002

DNA methylation in animal development

scientific article

DNMT1 deficiency triggers mismatch repair defects in human cells through depletion of repair protein levels in a process involving the DNA damage response.

scientific article published on 2 June 2011

Defending the genome from the enemy within: mechanisms of retrotransposon suppression in the mouse germline

scientific article published on 18 September 2013

Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver.

scientific article published on 17 April 2013

Effect of limited DNA methylation reprogramming in the normal sheep embryo on somatic cell nuclear transfer

scientific article published on 3 March 2004

Enzymatic approaches and bisulfite sequencing cannot distinguish between 5-methylcytosine and 5-hydroxymethylcytosine in DNA.

scientific article published on April 2010

Epigenetic profiles as defined signatures of xenobiotic exposure

scientific article published on 31 August 2013

Epigenetic reprogramming: preparing the epigenome for the next generation.

scientific article published on June 2013

Epigenetic silencing in embryogenesis

scientific article

Expression of a large LINE-1-driven antisense RNA is linked to epigenetic silencing of the metastasis suppressor gene TFPI-2 in cancer

scientific article published on 23 May 2013

From paramutation to paradigm

scientific article

Genetic and physical mapping of a gene encoding a methyl CpG binding protein, Mecp2, to the mouse X chromosome.

scientific article published on August 1994

Genomic insights into cancer-associated aberrant CpG island hypermethylation

scientific article

Hydroxymethylated DNA immunoprecipitation (hmeDIP).

scientific article published in January 2014

Investigating 5-hydroxymethylcytosine (5hmC): the state of the art.

scientific article published on January 2014

Kaiso is a genome-wide repressor of transcription that is essential for amphibian development

scientific article

LINE-1 activation and epigenetic silencing of suppressor genes in cancer: Causally related events?

scientific article published on September 2013

Lashings of DNA methylation, forkfuls of chromatin remodeling.

scientific article

Loss of the maintenance methyltransferase, xDnmt1, induces apoptosis in Xenopus embryos

scientific article published on 01 October 2019

MBD4 and MLH1 are required for apoptotic induction in xDNMT1-depleted embryos.

scientific article published in July 2009

Methylation-sensitive polymerase chain reaction

scientific article published in January 2006

Microarray analysis of LTR retrotransposon silencing identifies Hdac1 as a regulator of retrotransposon expression in mouse embryonic stem cells

scientific article

Molecular cloning and developmental expression of two Chloride Intracellular Channel (CLIC) genes in Xenopus laevis

scientific article

Multigenerational programming in the glucocorticoid programmed rat is associated with generation-specific and parent of origin effects ⬇️

scientific article published on November 1, 2011

Non-canonical functions of the DNA methylome in gene regulation

scientific article published on April 2013

Non-conservation of mammalian preimplantation methylation dynamics

scientific article published on 01 April 2004

Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome

scientific article (publication date: 3 October 2012)

Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline

scientific article

Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA

scientific article

Putting muscle in DNA methylation ⬇️

scientific article published on May 31, 2011

Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes

scientific article

Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise ⬇️

scientific article published on November 19, 2010

Senescent cells harbour features of the cancer epigenome.

scientific article published on 24 November 2013

Shoring up DNA methylation and H3K27me3 domain demarcation at developmental genes

scientific article published on 22 November 2017

Targeting of Rac GTPases blocks the spread of intact human breast cancer.

scientific article

The CXXC-TET bridge--mind the methylation gap!

scientific article published on 28 May 2013

The effect of interspecific oocytes on demethylation of sperm DNA.

scholarly article

The genome-defence gene Tex19.1 suppresses LINE-1 retrotransposons in the placenta and prevents intra-uterine growth retardation in mice

scientific journal article

The interaction of xKaiso with xTcf3: a revised model for integration of epigenetic and Wnt signalling pathways ⬇️

scientific article published on 21 January 2009

The non-methylated DNA-binding function of Kaiso is not required in early Xenopus laevis development

scientific article published on 21 January 2009

Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns

scientific article

Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes

scientific article

Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer.

scientific article

xDnmt1 regulates transcriptional silencing in pre-MBT Xenopus embryos independently of its catalytic function

scientific article

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