List of works - Martin J. Lear

A Direct and Efficientα-Selective Glycosylation Protocol for the Kedarcidin Sugar,L-Mycarose: AgPF6 as a Remarkable Activator of 2-Deoxythioglycosides

scientific article published on 01 March 2001

A bismuth(III)-catalyzed Friedel-Crafts cyclization and stereocontrolled organocatalytic approach to (-)-platensimycin

scientific article published on 29 October 2010

A convergent total synthesis of the kedarcidin chromophore: 20-years in the making

scientific article published on 25 March 2019

A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases.

scientific article

A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria

scientific article

Absolute Configuration and Total Synthesis of a Novel Antimalarial Lipopeptide by the de Novo Preparation of Chiral Nonproteinogenic Amino Acids

scientific article published in 2012

Activity-based proteome profiling of potential cellular targets of Orlistat--an FDA-approved drug with anti-tumor activities

scientific article

Autoinductive conversion of α,α-diiodonitroalkanes to amides and esters catalysed by iodine byproducts under O2

scholarly article by Jing Li et al published 2018 in Chemical Communications

Biomimetic Total Synthesis of Cyanosporaside Aglycons from a Single Enediyne Precursor through Site-Selectivep-Benzyne Hydrochlorination

scholarly article by Kei Yamada et al published 8 October 2014 in Angewandte Chemie International Edition

Characterization of the commercially-available fluorescent chloroquine-BODIPY conjugate, LynxTag-CQGREEN, as a marker for chloroquine resistance and uptake in a 96-well plate assay

scientific article

Chemical Modification and Organelle-Specific Localization of Orlistat-Like Natural-Product-Based Probes

article

Click-based synthesis and proteomic profiling of lipstatin analogues

scientific article

Diverted total synthesis of falcitidin acyl tetrapeptides as new antimalarial leads

Efficient Construction of the Kedarcidin Chromophore Ansamacrolide

scientific article published on 01 January 2005

Evaluation of aroma-active compounds in Pontianak orange peel oil ( Citrus nobilis Lour. Var. microcarpa Hassk.) by gas chromatography-olfactometry, aroma reconstitution, and omission test

scientific article

Identification of the binding of sceptrin to MreB via a bidirectional affinity protocol.

scientific article

Isolation and synthesis of falcitidin, a novel myxobacterial-derived acyltetrapeptide with activity against the malaria target falcipain-2.

scientific article published on 23 January 2013

Laetirobin from the Parasitic Growth ofLaetiporus sulphureusonRobinia pseudoacacia

article

Lipidomic analysis of human tear fluid reveals structure-specific lipid alterations in dry eye syndrome

scientific article

Mechanism of Oxidative Amidation of Nitroalkanes with Oxygen and Amine Nucleophiles by Using Electrophilic Iodine.

scientific article published on 3 March 2016

Oxidative Amidation of Nitroalkanes with Amine Nucleophiles using Molecular Oxygen and Iodine.

scientific article

Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti Trypanosoma brucei agent

scientific article

Practical synthesis of maleimides and coumarin-linked probes for protein and antibody labelling via reduction of native disulfides

scientific article published on 3 July 2009

Rapid and sensitive profiling of tear wax ester species using high performance liquid chromatography coupled with tandem mass spectrometry

scientific article published on 8 August 2013

Singapore R&D and globetrotting

scientific article published on 01 February 2009

Spin Trapping of13C-Labeledp-Benzynes Generated by Masamune–Bergman Cyclization of Bicyclic Nine-Membered Enediynes

scholarly article by Toyonobu Usuki et al published 4 October 2004 in Angewandte Chemie International Edition

Sterically Demanding Oxidative Amidation of α-Substituted Malononitriles with Amines Using O2

scientific article published on 14 June 2016

Synthesis of 13C-labelled, bicyclic mimetics of natural enediynes

scientific article published on 01 November 2002

Synthesis of 2-C-methylerythritols and 2-C-methylthreitols via enantiodivergent Sharpless dihydroxylation of trisubstituted olefins

Synthesis of the entire carbon framework of the kedarcidin chromophore aglycon

scientific article published on 29 June 2007

The first total synthesis of N1999-A2: absolute stereochemistry and stereochemical implications into DNA cleavage

scientific article published in November 2001

Total synthesis confirms laetirobin as a formal Diels-Alder adduct

scientific article published in February 2010

Total synthesis of (-)-platensimycin by advancing oxocarbenium- and iminium-mediated catalytic methods

scientific article published on 22 July 2014

Transient Brewster angle reflectometry of spiropyran monolayers

scientific article

Transient absorption spectroscopy on spiropyran monolayers using nanosecond pump-probe Brewster angle reflectometry.

scientific article

Use of Polystyrene-Supported DBU in the Synthesis and α-Selective Glycosylation Study of the Unstable Schmidt Donor ofl-Kedarosamine

scientific article published on 01 March 2004

List of works by Martin J. Lear

A Direct and Efficientα-Selective Glycosylation Protocol for the Kedarcidin Sugar,L-Mycarose: AgPF6 as a Remarkable Activator of 2-Deoxythioglycosides

A bismuth(III)-catalyzed Friedel-Crafts cyclization and stereocontrolled organocatalytic approach to (-)-platensimycin

A convergent total synthesis of the kedarcidin chromophore: 20-years in the making

A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases.

A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria

Absolute Configuration and Total Synthesis of a Novel Antimalarial Lipopeptide by the de Novo Preparation of Chiral Nonproteinogenic Amino Acids

Activity-based proteome profiling of potential cellular targets of Orlistat--an FDA-approved drug with anti-tumor activities

Autoinductive conversion of α,α-diiodonitroalkanes to amides and esters catalysed by iodine byproducts under O2

Biomimetic Total Synthesis of Cyanosporaside Aglycons from a Single Enediyne Precursor through Site-Selectivep-Benzyne Hydrochlorination

Characterization of the commercially-available fluorescent chloroquine-BODIPY conjugate, LynxTag-CQGREEN, as a marker for chloroquine resistance and uptake in a 96-well plate assay

Chemical Modification and Organelle-Specific Localization of Orlistat-Like Natural-Product-Based Probes

Click-based synthesis and proteomic profiling of lipstatin analogues

Diverted total synthesis of falcitidin acyl tetrapeptides as new antimalarial leads

Efficient Construction of the Kedarcidin Chromophore Ansamacrolide

Evaluation of aroma-active compounds in Pontianak orange peel oil ( Citrus nobilis Lour. Var. microcarpa Hassk.) by gas chromatography-olfactometry, aroma reconstitution, and omission test

Identification of the binding of sceptrin to MreB via a bidirectional affinity protocol.

Isolation and synthesis of falcitidin, a novel myxobacterial-derived acyltetrapeptide with activity against the malaria target falcipain-2.

Laetirobin from the Parasitic Growth ofLaetiporus sulphureusonRobinia pseudoacacia

Lipidomic analysis of human tear fluid reveals structure-specific lipid alterations in dry eye syndrome

Mechanism of Oxidative Amidation of Nitroalkanes with Oxygen and Amine Nucleophiles by Using Electrophilic Iodine.

Oxidative Amidation of Nitroalkanes with Amine Nucleophiles using Molecular Oxygen and Iodine.

Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti Trypanosoma brucei agent

Practical synthesis of maleimides and coumarin-linked probes for protein and antibody labelling via reduction of native disulfides

Rapid and sensitive profiling of tear wax ester species using high performance liquid chromatography coupled with tandem mass spectrometry

Singapore R&D and globetrotting

Spin Trapping of13C-Labeledp-Benzynes Generated by Masamune–Bergman Cyclization of Bicyclic Nine-Membered Enediynes

Sterically Demanding Oxidative Amidation of α-Substituted Malononitriles with Amines Using O2

Synthesis of 13C-labelled, bicyclic mimetics of natural enediynes

Synthesis of 2-C-methylerythritols and 2-C-methylthreitols via enantiodivergent Sharpless dihydroxylation of trisubstituted olefins

Synthesis of the entire carbon framework of the kedarcidin chromophore aglycon

The first total synthesis of N1999-A2: absolute stereochemistry and stereochemical implications into DNA cleavage

Total synthesis confirms laetirobin as a formal Diels-Alder adduct

Total synthesis of (-)-platensimycin by advancing oxocarbenium- and iminium-mediated catalytic methods

Transient Brewster angle reflectometry of spiropyran monolayers

Transient absorption spectroscopy on spiropyran monolayers using nanosecond pump-probe Brewster angle reflectometry.

Use of Polystyrene-Supported DBU in the Synthesis and α-Selective Glycosylation Study of the Unstable Schmidt Donor ofl-Kedarosamine