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List of works by Michael D. B. Swedberg

1,2,5-Thiadiazole analogues of aceclidine as potent m1 muscarinic agonists.

scientific article

3-(5-Alkylamino-4-isoxazolyl)-1,2,5,6-tetrahydropyridines: a novel class of central nicotinic receptor ligands.

scientific article published on September 1998

A multi-site comparison of in vivo safety pharmacology studies conducted to support ICH S7A & B regulatory submissions.

scientific article published on 09 May 2013

A proactive nonclinical drug abuse and dependence liability assessment strategy: a sponsor perspective

scientific article published on September 2013

A repeated test procedure to assess onset and duration of the cue properties of (-) delta 9-THC, (-) delta 8-THC-DMH and (+) delta 8-THC.

scientific article published in January 1981

AZD9272 and AZD2066: selective and highly central nervous system penetrant mGluR5 antagonists characterized by their discriminative effects.

scientific article published on 29 May 2014

Conformationally constrained analogues of the muscarinic agonist 3-(4-(methylthio)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyr idine. Synthesis, receptor affinity, and antinociceptive activity

scientific article published in January 1998

Discriminative stimulus effects of intravenous l-nicotine and nicotine analogs or metabolites in squirrel monkeys

scientific article published in January 1989

Discriminative stimulus functions of CNS sedative drugs assessed by drug versus drug discrimination procedures in gerbils

scientific article published in January 1998

Discriminative stimulus properties of drugs: a brief history and a selective review.

scientific article published on January 1982

Drug discrimination procedures: differential characteristics of the drug A vs drug B and the drug A vs drug B vs no drug cases

scientific article published in January 1986

Drug discrimination: A versatile tool for characterization of CNS safety pharmacology and potential for drug abuse

scientific article published on 25 May 2016

Effects of chlormethiazole (Heminevrin®) on drug discrimination and open-field behavior in gerbils ⬇️

scientific article published on October 31, 1978

Effects of the δ opioid agonist AZD2327 upon operant behaviors and assessment of its potential for abuse

scientific article

Establishment of auditory discrimination and detection of tinnitus induced by salicylic acid and intense tone exposure in the rat.

scientific article published on 25 March 2013

Evidence supporting lack of discriminative stimulus properties of a combination of naltrexone and morphine

scientific article published on April 1, 1979

In vivo labeling of the central GABA uptake carrier with 3H-Tiagabine

scientific article published on January 1, 1992

Muscarinic agonists as analgesics. Antinociceptive activity versus M1 activity: SAR of alkylthio-TZTP's and related 1,2,5-thiadiazole analogs

scientific article published on 01 January 1995

Muscarinic receptor agonists decrease cocaine self-administration rates in drug-naive mice.

scientific article published in August 2000

NNC-19-1228 and NNC 22-0031, novel neuroleptics with a "mesolimbic-selective" behavioral profile

scientific article published in January 1997

Potential role of muscarinic receptors in schizophrenia

scientific article published in January 1999

Preclinical pharmacology of AZD2327: a highly selective agonist of the δ-opioid receptor

scientific article

Prediction and modeling of effects on the QTc interval for clinical safety margin assessment, based on single-ascending-dose study data with AZD3839.

scientific article

Reinforcing effects of nicotinic compounds: intravenous self-administration in drug-naive mice

scientific article published in June 1998

Role of central noradrenaline neurons in the contextual control of latent inhibition in taste aversion learning

scientific article published in August 1986

Synthesis of novel GABA uptake inhibitors. 3. Diaryloxime and diarylvinyl ether derivatives of nipecotic acid and guvacine as anticonvulsant agents.

scientific article

Synthesis of novel GABA uptake inhibitors. 4. Bioisosteric transformation and successive optimization of known GABA uptake inhibitors leading to a series of potent anticonvulsant drug candidates

scientific article published on 01 October 1999

Synthesis of novel GABA uptake inhibitors. Part 6: preparation and evaluation of N-Omega asymmetrically substituted nipecotic acid derivatives

scientific article

Synthesis of novel gamma-aminobutyric acid (GABA) uptake inhibitors. 5.(1) Preparation and structure-activity studies of tricyclic analogues of known GABA uptake inhibitors

scientific article published in June 2001

The gamma-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracellular brain levels of GABA in awake rats.

scientific article published in September 1992

The muscarinic receptor agonist BuTAC, a novel potential antipsychotic, does not impair learning and memory in mouse passive avoidance

scientific article

Unexpected antipsychotic-like activity with the muscarinic receptor ligand (5R,6R)6-(3-propylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane .

scientific article published in September 1998

mGluR5 antagonist-induced psychoactive properties: MTEP drug discrimination, a pharmacologically selective non-NMDA effect with apparent lack of reinforcing properties

scientific article

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