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List of works by Alexandru Saveanu

A Novel Dysfunctional LHX4 Mutation with High Phenotypical Variability in Patients with Hypopituitarism

scientific article published on 29 April 2008

A potential inhibitory role for the new truncated variant of somatostatin receptor 5, sst5TMD4, in pituitary adenomas poorly responsive to somatostatin analogs

scientific article published on 16 March 2010

An Uncommon Phenotype with Familial Central Hypogonadism Caused by a NovelPROP1Gene Mutant Truncated in the Transactivation Domain

article

Anti-proliferative and anti-secretory effects of everolimus on human pancreatic neuroendocrine tumors primary cultures: is there any benefit from combination with somatostatin analogs?

scientific article published on 10 April 2017

Balance between somatostatin and D2 receptor expression drives TSH-secreting adenoma response to somatostatin analogues and dopastatins.

scientific article

Cancerous leptomeningitis and familial congenital hypopituitarism

scientific article

Case seminar: a young female with acute hyponatremia and a sellar mass

scientific article published on 24 August 2011

Combined pituitary hormone deficiency: current and future status

scientific article

Demonstration of enhanced potency of a chimeric somatostatin-dopamine molecule, BIM-23A387, in suppressing growth hormone and prolactin secretion from human pituitary somatotroph adenoma cells.

scientific article published in December 2002

Detection of genetic hypopituitarism in an adult population of idiopathic pituitary insufficiency patients with growth hormone deficiency.

scientific article published in September 2011

Déficit hypophysaire combiné multiple : aspects cliniques et génétiques

scientific article published on 01 February 2008

Efficacy of a dopamine-somatostatin chimeric molecule, BIM-23A760, in the control of cell growth from primary cultures of human non-functioning pituitary adenomas: a multi-center study.

scientific article published in June 2008

Efficacy of chimeric molecules directed towards multiple somatostatin and dopamine receptors on inhibition of GH and prolactin secretion from GH-secreting pituitary adenomas classified as partially responsive to somatostatin analog therapy.

scientific article published in July 2005

Expression of somatostatin receptors, dopamine D₂ receptors, noradrenaline transporters, and vesicular monoamine transporters in 52 pheochromocytomas and paragangliomas.

scientific article

GPR101 Mutations are not a Frequent Cause of Congenital Isolated Growth Hormone Deficiency

scientific article published on 21 January 2016

Genetic causes of combined pituitary hormone deficiencies in humans ⬇️

scientific article published on April 21, 2012

Genetic screening of combined pituitary hormone deficiency: experience in 195 patients

scientific article published on 30 May 2006

Human somatostatin receptor subtypes in acromegaly: distinct patterns of messenger ribonucleic acid expression and hormone suppression identify different tumoral phenotypes

scientific article published on 01 February 2000

Identification and functional analysis of the novel S179R POU1F1 mutation associated with combined pituitary hormone deficiency

scientific article published on 12 September 2006

Identifying the Deleterious Effect of Rare LHX4 Allelic Variants, a Challenging Issue

scientific article published on 8 May 2015

In vivo and in vitro response to octreotide LAR in a TSH-secreting adenoma: characterization of somatostatin receptor expression and role of subtype 5

scientific article published on 18 November 2010

Lanreotide for the treatment of acromegaly.

scientific article published on 16 June 2009

Lessons from monogenic causes of growth hormone deficiency

scientific article published on 5 May 2017

MECHANISMS IN ENDOCRINOLOGY: An update in the genetic aetiologies of combined pituitary hormone deficiency

scientific article

Mécanismes de tumorigenèse hypophysaire

scientific article published on 19 October 2008

Neuroendocrine tumors: insights into innovative therapeutic options and rational development of targeted therapies.

scientific article published on 27 October 2013

Novel chimeric somatostatin analogs: facts and perspectives.

scientific article published on April 2007

Novel modalities of somatostatin actions.

scientific article

Novel mutations within the POU1F1 gene associated with variable combined pituitary hormone deficiency.

scientific article published on 31 May 2005

Octreotide therapy in meningiomas: in vitro study, clinical correlation, and literature review

scientific article published on 16 December 2016

PROKR2 variants in multiple hypopituitarism with pituitary stalk interruption.

scientific article published on 30 March 2012

Pasireotide and octreotide antiproliferative effects and sst2 trafficking in human pancreatic neuroendocrine tumor cultures

article

Physiopathology of somatolactotroph cells: from transduction mechanisms to cotargeting therapy.

scientific article published on March 2011

Pituitary hormone deficiencies due to transcription factor gene alterations.

scientific article

Pituitary stalk interruption and olfactory bulbs aplasia/hypoplasia in a man with Kallmann syndrome and reversible gonadotrope and somatotrope deficiencies

scientific article published on 9 November 2014

Pituitary stalk interruption syndrome in 83 patients: novel HESX1 mutation and severe hormonal prognosis in malformative forms.

scientific article

Quelles causes génétiques rechercher en présence d’un déficit en hormone de croissance ?

scientific article published on 15 April 2011

Rapid pituitary tumor shrinkage with dissociation between antiproliferative and antisecretory effects of a long-acting octreotide in an acromegalic patient

scientific article published on 20 February 2007

Relevance of coexpression of somatostatin and dopamine D2 receptors in pituitary adenomas.

scientific article published on 23 December 2007

Somatostatin and dopamine receptor expression in lung carcinoma cells and effects of chimeric somatostatin-dopamine molecules on cell proliferation.

scientific article

Somatostatin and dopamine-somatostatin multiple ligands directed towards somatostatin and dopamine receptors in pituitary adenomas

scientific article published on 13 October 2006

Somatostatin receptor sst2 gene transfer in human prolactinomas in vitro: Impact on sensitivity to dopamine, somatostatin and dopastatin, in the control of prolactin secretion

article

Somatostatin-dopamine ligands in the treatment of pituitary adenomas.

scientific article published on 24 July 2008

Targeting Dopamine Receptors Subtype 2 (D2DR) in Pheochromocytomas: Head-to-Head Comparison Between In Vitro and In Vivo Findings

scientific article published on 05 September 2013

The analysis of quantitative expression of somatostatin and dopamine receptors in gastro-entero-pancreatic tumours opens new therapeutic strategies

scientific article published in December 2006

Unilateral agenesis of internal carotid artery associated with congenital combined pituitary hormone deficiency and pituitary stalk interruption without HESX1, LHX4 or OTX2 mutation: a case report.

scientific article published in December 2012

[Congenital hypopituitarism: when should transcription factor gene screenings be performed?]

scientific article published on 01 March 2004

[Genetics of anterior hypopituitary diseases]

scientific article published on 01 June 2005

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