List of works - Tomoya Hirano

6-Arylcoumarin as a Scaffold of Photofunctional Molecules with OFF-ON-OFF Type Regulation

scientific article published on 27 December 2020

6-arylcoumarins as novel nonsteroidal type progesterone antagonists: an example with receptor-binding-dependent fluorescence

scientific article published on 5 October 2011

A Polarity-Sensitive Fluorescent Amino Acid and its Incorporation into Peptides for the Ratiometric Detection of Biomolecular Interactions

scientific article published on 13 October 2019

A novel fluorescent probe for zinc ion based on boron dipyrromethene (BODIPY) chromophore

scientific article

A novel, cell-permeable, fluorescent probe for ratiometric imaging of zinc ion.

scientific article

ASKA technology-based pull-down method reveals a suppressive effect of ASK1 on the inflammatory NOD-RIPK2 pathway in brown adipocytes

scientific article published on 10 November 2021

Boron cluster-based development of potent nonsecosteroidal vitamin D receptor ligands: direct observation of hydrophobic interaction between protein surface and carborane

scientific article

Design and synthesis of 4-benzyl-1-(2H)-phthalazinone derivatives as novel androgen receptor antagonists.

scientific article published on 6 August 2015

Design and synthesis of tetraol derivatives of 1,12-dicarba- closo -dodecaborane as non-secosteroidal vitamin D analogs

scientific article published on 06 August 2014

Development of 6-arylcoumarins as nonsteroidal progesterone antagonists. Structure-activity relationships and fluorescence properties.

scientific article published on 12 September 2016

Development of Novel Inhibitors for Histone Methyltransferase SET7/9 based on Cyproheptadine

scientific article published on 06 July 2018

Development of a library of 6-arylcoumarins as candidate fluorescent sensors

scientific article

Development of functional molecules for elucidation of the physiological roles of several nuclear receptors and their endogenous ligands.

scientific article

Development of novel bisubstrate-type inhibitors of histone methyltransferase SET7/9.

scientific article published on 14 October 2010

Evidence for pH dependent Zn2+influx in K562 erythroleukemia cells: studies using ZnAF-2F fluorescence and 65Zn2+ uptake

scientific article published on 8 September 2005

Identification of Cyproheptadine as an Inhibitor of SET Domain Containing Lysine Methyltransferase 7/9 (Set7/9) That Regulates Estrogen-Dependent Transcription

scientific article

Identification of absolute helical structures of aromatic multilayered oligo(m-phenylurea)s in solution.

scientific article published in November 2009

Improvement and biological applications of fluorescent probes for zinc, ZnAFs

scientific article published in June 2002

Isolation and identification of C-19 fatty acids with anti-tumor activity from the spores of Ganoderma lucidum (reishi mushroom)

scientific article published on 30 December 2011

Modulation of intramolecular heterodimer-induced fluorescence quenching of tricarbocyanine dye for the development of fluorescent sensor

scientific article published on 08 October 2010

Mossy fiber Zn2+ spillover modulates heterosynaptic N-methyl-D-aspartate receptor activity in hippocampal CA3 circuits.

scientific article published on 15 July 2002

Novel thyroid hormone receptor antagonists with an N-alkylated diphenylamine skeleton.

scientific article published on 3 March 2007

Steric structure-activity relationship of cyproheptadine derivatives as inhibitors of histone methyltransferase Set7/9.

scientific article published on 12 July 2016

Structural development of p-carborane-based potent non-secosteroidal vitamin D analogs

scientific article published on 16 September 2014

Structures of histone methyltransferase SET7/9 in complexes with adenosylmethionine derivatives

scientific article

Synthesis and structure–activity relationship of p-carborane-based non-secosteroidal vitamin D analogs

scientific article published on 21 January 2014

Thyromimetics: a review of recent reports and patents (2004 - 2009).

scientific article published on February 2010

List of works by Tomoya Hirano

6-Arylcoumarin as a Scaffold of Photofunctional Molecules with OFF-ON-OFF Type Regulation

6-arylcoumarins as novel nonsteroidal type progesterone antagonists: an example with receptor-binding-dependent fluorescence

A Polarity-Sensitive Fluorescent Amino Acid and its Incorporation into Peptides for the Ratiometric Detection of Biomolecular Interactions

A novel fluorescent probe for zinc ion based on boron dipyrromethene (BODIPY) chromophore

A novel, cell-permeable, fluorescent probe for ratiometric imaging of zinc ion.

ASKA technology-based pull-down method reveals a suppressive effect of ASK1 on the inflammatory NOD-RIPK2 pathway in brown adipocytes﻿

Boron cluster-based development of potent nonsecosteroidal vitamin D receptor ligands: direct observation of hydrophobic interaction between protein surface and carborane

Design and synthesis of 4-benzyl-1-(2H)-phthalazinone derivatives as novel androgen receptor antagonists.

Design and synthesis of tetraol derivatives of 1,12-dicarba- closo -dodecaborane as non-secosteroidal vitamin D analogs

Development of 6-arylcoumarins as nonsteroidal progesterone antagonists. Structure-activity relationships and fluorescence properties.

Development of Novel Inhibitors for Histone Methyltransferase SET7/9 based on Cyproheptadine

Development of a library of 6-arylcoumarins as candidate fluorescent sensors

Development of functional molecules for elucidation of the physiological roles of several nuclear receptors and their endogenous ligands.

Development of novel bisubstrate-type inhibitors of histone methyltransferase SET7/9.

Evidence for pH dependent Zn2+influx in K562 erythroleukemia cells: studies using ZnAF-2F fluorescence and 65Zn2+ uptake

Identification of Cyproheptadine as an Inhibitor of SET Domain Containing Lysine Methyltransferase 7/9 (Set7/9) That Regulates Estrogen-Dependent Transcription

Identification of absolute helical structures of aromatic multilayered oligo(m-phenylurea)s in solution.

Improvement and biological applications of fluorescent probes for zinc, ZnAFs

Isolation and identification of C-19 fatty acids with anti-tumor activity from the spores of Ganoderma lucidum (reishi mushroom)

Modulation of intramolecular heterodimer-induced fluorescence quenching of tricarbocyanine dye for the development of fluorescent sensor

Mossy fiber Zn2+ spillover modulates heterosynaptic N-methyl-D-aspartate receptor activity in hippocampal CA3 circuits.

Novel thyroid hormone receptor antagonists with an N-alkylated diphenylamine skeleton.

Steric structure-activity relationship of cyproheptadine derivatives as inhibitors of histone methyltransferase Set7/9.

Structural development of p-carborane-based potent non-secosteroidal vitamin D analogs

Structures of histone methyltransferase SET7/9 in complexes with adenosylmethionine derivatives

Synthesis and structure–activity relationship of p-carborane-based non-secosteroidal vitamin D analogs

Thyromimetics: a review of recent reports and patents (2004 - 2009).

ASKA technology-based pull-down method reveals a suppressive effect of ASK1 on the inflammatory NOD-RIPK2 pathway in brown adipocytes