List of works - Hongmin Zhang

"Anion clamp" allows flexible protein to impose coordination geometry on metal ions

scientific article

A Conserved Hydrophobic Patch on Vβ Domains Revealed by TCRβ Chain Crystal Structures: Implications for Pre-TCR Dimerization

scientific article

Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1

article

An Unusual Allosteric Mobility of the C-Terminal Helix of a High-Affinity αL Integrin I Domain Variant Bound to ICAM-5

scientific article

Bacterial lipoprotein biosynthetic pathway as a potential target for structure-based design of antibacterial agents

scientific article published on 01 January 2020

Bismuth antimicrobial drugs serve as broad-spectrum metallo-β-lactamase inhibitors.

scientific article

Catalysis-based inhibitors of the calcium signaling function of CD38

scientific article

Crystal structure of NDM‐1 reveals a common β‐lactam hydrolysis mechanism ⬇️

scientific article published on April 20, 2011

Crystal structure of isoflurane bound to integrin LFA-1 supports a unified mechanism of volatile anesthetic action in the immune and central nervous systems

scientific article

Cyclic adenosine 5'-diphosphate ribose analogs without a "southern" ribose inhibit ADP-ribosyl cyclase-hydrolase CD38.

scientific article published on October 2014

Cytosolic CD38 protein forms intact disulfides and is active in elevating intracellular cyclic ADP-ribose

scientific article

Dynamic Conformations of the CD38-Mediated NAD Cyclization Captured in a Single Crystal ⬇️

scientific article published on December 8, 2010

High resolution crystal structure of the catalytic domain of MCR-1.

scientific article published on 21 December 2016

Iron and bismuth bound human serum transferrin reveals a partially-opened conformation in the N-lobe

scientific article

Mass production of active recombinant Chryseobacterium proteolyticum protein glutaminase in Escherichia coli using a sequential dual expression system and one-step purification

scientific article published on 22 August 2020

Mp1p Is a Virulence Factor in Talaromyces (Penicillium) marneffei

scientific article

N-thiadiazole-4-hydroxy-2-quinolone-3-carboxamides bearing heteroaromatic rings as novel antibacterial agents: Design, synthesis, biological evaluation and target identification

scientific article published on 30 December 2019

Pose Filter-Based Ensemble Learning Enables Discovery of Orally Active, Nonsteroidal Farnesoid X Receptor Agonists

scientific article published on 25 February 2020

Purification, partial characterization, crystallization and structural determination of AHP-LAAO, a novel L-amino-acid oxidase with cell apoptosis-inducing activity from Agkistrodon halys pallas venom

scientific article published on 21 April 2004

Structural Basis for Human PECAM-1-Mediated Trans-homophilic Cell Adhesion.

scientific article published on 13 December 2016

Structural Basis for RNA Binding and Homo-Oligomer Formation by Influenza B Virus Nucleoprotein

scientific article

Structural basis of activation-dependent binding of ligand-mimetic antibody AL-57 to integrin LFA-1

scientific article

Structural insight into a matured humanized monoclonal antibody HuA21 against HER2-overexpressing cancer cells

scientific article published on 31 May 2019

Talaromyces marneffei Mp1 Protein, a Novel Virulence Factor, Carries Two Arachidonic Acid-Binding Domains To Suppress Inflammatory Responses in Hosts

scientific article published on 25 March 2019

Talaromyces marneffei Mp1p Is a Virulence Factor that Binds and Sequesters a Key Proinflammatory Lipid to Dampen Host Innate Immune Response.

scientific article published on 16 January 2017

The Bicyclic Intermediate Structure Provides Insights into the Desuccinylation Mechanism of Human Sirtuin 5 (SIRT5) ⬇️

scientific article published on July 5, 2012

The STAT3 inhibitor S3I-201 suppresses fibrogenesis and angiogenesis in liver fibrosis

scientific article published on 11 September 2018

List of works by Hongmin Zhang

"Anion clamp" allows flexible protein to impose coordination geometry on metal ions

A Conserved Hydrophobic Patch on Vβ Domains Revealed by TCRβ Chain Crystal Structures: Implications for Pre-TCR Dimerization

Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1

An Unusual Allosteric Mobility of the C-Terminal Helix of a High-Affinity αL Integrin I Domain Variant Bound to ICAM-5

Bacterial lipoprotein biosynthetic pathway as a potential target for structure-based design of antibacterial agents

Bismuth antimicrobial drugs serve as broad-spectrum metallo-β-lactamase inhibitors.

Catalysis-based inhibitors of the calcium signaling function of CD38

Crystal structure of NDM‐1 reveals a common β‐lactam hydrolysis mechanism ⬇️

Crystal structure of isoflurane bound to integrin LFA-1 supports a unified mechanism of volatile anesthetic action in the immune and central nervous systems

Cyclic adenosine 5'-diphosphate ribose analogs without a "southern" ribose inhibit ADP-ribosyl cyclase-hydrolase CD38.

Cytosolic CD38 protein forms intact disulfides and is active in elevating intracellular cyclic ADP-ribose

Dynamic Conformations of the CD38-Mediated NAD Cyclization Captured in a Single Crystal ⬇️

High resolution crystal structure of the catalytic domain of MCR-1.

Iron and bismuth bound human serum transferrin reveals a partially-opened conformation in the N-lobe

Mass production of active recombinant Chryseobacterium proteolyticum protein glutaminase in Escherichia coli using a sequential dual expression system and one-step purification

Mp1p Is a Virulence Factor in Talaromyces (Penicillium) marneffei

N-thiadiazole-4-hydroxy-2-quinolone-3-carboxamides bearing heteroaromatic rings as novel antibacterial agents: Design, synthesis, biological evaluation and target identification

Pose Filter-Based Ensemble Learning Enables Discovery of Orally Active, Nonsteroidal Farnesoid X Receptor Agonists

Purification, partial characterization, crystallization and structural determination of AHP-LAAO, a novel L-amino-acid oxidase with cell apoptosis-inducing activity from Agkistrodon halys pallas venom

Structural Basis for Human PECAM-1-Mediated Trans-homophilic Cell Adhesion.

Structural Basis for RNA Binding and Homo-Oligomer Formation by Influenza B Virus Nucleoprotein

Structural basis of activation-dependent binding of ligand-mimetic antibody AL-57 to integrin LFA-1

Structural insight into a matured humanized monoclonal antibody HuA21 against HER2-overexpressing cancer cells

Talaromyces marneffei Mp1 Protein, a Novel Virulence Factor, Carries Two Arachidonic Acid-Binding Domains To Suppress Inflammatory Responses in Hosts

Talaromyces marneffei Mp1p Is a Virulence Factor that Binds and Sequesters a Key Proinflammatory Lipid to Dampen Host Innate Immune Response.

The Bicyclic Intermediate Structure Provides Insights into the Desuccinylation Mechanism of Human Sirtuin 5 (SIRT5) ⬇️

The STAT3 inhibitor S3I-201 suppresses fibrogenesis and angiogenesis in liver fibrosis