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List of works by Brian Smith

Acetyl-lysine analog peptides as mechanistic probes of protein deacetylases

scientific article published on 19 October 2007

Chemoproteomic Strategy to Quantitatively Monitor Transnitrosation Uncovers Functionally Relevant S-Nitrosation Sites on Cathepsin D and HADH2.

scientific article published on 7 June 2016

Coenzyme specificity of Sir2 protein deacetylases: implications for physiological regulation

scientific article

Comparative and integrative metabolomics reveal that -nitrosation inhibits physiologically relevant metabolic enzymes

scientific article published on 26 February 2018

Covalent-Fragment Screening of BRD4 Identifies a Ligandable Site Orthogonal to the Acetyl-Lysine Binding Sites

scientific article published on 23 March 2020

Current Trends in Sirtuin Activator and Inhibitor Development

scientific article published in 2024

Human sirtuins are differentially sensitive to inhibition by nitrosating agents and other cysteine oxidants

scientific article published on 05 May 2020

Hydrolysis of O-acetyl-ADP-ribose isomers by ADP-ribosylhydrolase 3.

scientific article

Linking SIRT2 to Parkinson's disease.

scientific article published in August 2007

Mechanism and kinetics of inducible nitric oxide synthase auto-S-nitrosation and inactivation

scientific article published on 24 January 2012

Mechanism of Sirt1 NAD+-dependent Protein Deacetylase Inhibition by Cysteine S-Nitrosation.

scientific article published on 18 October 2016

Mechanism of human SIRT1 activation by resveratrol

scientific article (publication date: 29 April 2005)

Mechanism-based inhibition of Sir2 deacetylases by thioacetyl-lysine peptide

scientific article published on 21 November 2007

Mechanisms and molecular probes of sirtuins.

scientific article published on October 2008

Mechanisms of S-nitrosothiol formation and selectivity in nitric oxide signaling

scientific article

Metabolically Derived Lysine Acylations and Neighboring Modifications Tune the Binding of the BET Bromodomains to Histone H4.

scientific article

Molecular architecture of mammalian nitric oxide synthases

scientific article

Nitric Oxide Mediates Biofilm Formation and Symbiosis in Silicibacter sp. Strain TrichCH4B

scientific article published on 5 May 2015

Nitric oxide synthase domain interfaces regulate electron transfer and calmodulin activation

scientific article published on 03 September 2013

Nitrosothiol formation and S-nitrosation signaling through nitric oxide synthases

scientific article published on 5 October 2016

Reply

scientific article published on 27 May 2015

SIRT3 substrate specificity determined by peptide arrays and machine learning

scientific article

Sir2 deacetylases exhibit nucleophilic participation of acetyl-lysine in NAD+ cleavage.

scientific article published on 17 April 2007

Sir2 protein deacetylases: evidence for chemical intermediates and functions of a conserved histidine.

scientific article published on January 2006

Sirt3 Promotes the Urea Cycle and Fatty Acid Oxidation during Dietary Restriction

scientific article published on January 21, 2011

Sirtuins Caught in the Act

scientific article published on 01 August 2006

Structural and Kinetic Isotope Effect Studies of Nicotinamidase (Pnc1) from Saccharomyces cerevisiae

scientific article

Truncating Mutation in the Nitric Oxide Synthase 1 Gene Is Associated With Infantile Achalasia

article

Validation and Characterization of Five Distinct Novel Inhibitors of Human Cytomegalovirus

scientific article published on 27 March 2020