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List of works by Darin E. Jones

An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation

scientific article published on 03 March 2021

Analysis of Plant-Plant Interactions Reveals the Presence of Potent Antileukemic Compounds

scientific article published on 04 May 2022

Chemical screening by time-resolved X-ray scattering to discover allosteric probes

scientific article published in 2024

Dehydroleucodine, a Sesquiterpene Lactone from Gynoxys verrucosa, Demonstrates Cytotoxic Activity against Human Leukemia Cells

scientific article published on 8 April 2016

Discovery and SAR of PF-4693627, a potent, selective and orally bioavailable mPGES-1 inhibitor for the potential treatment of inflammation

scientific article published on 6 December 2012

Inhibitors of HGFA, Matriptase, and Hepsin Serine Proteases: A Nonkinase Strategy to Block Cell Signaling in Cancer

scientific article published on 9 October 2014

Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death

scientific article published on 11 December 2019

Structure-activity relationships among DNA ligase inhibitors: Characterization of a selective uncompetitive DNA ligase I inhibitor

scientific article published on 10 October 2017

Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets.

scientific article published on 4 April 2015

Structure-based drug design of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex.

scientific article

Synthesis, Crystallography, and Anti-Leukemic Activity of the Amino Adducts of Dehydroleucodine

scientific article published on 20 October 2020

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