Search filters

List of works by Genevieve Evans

A covalent adduct of MbtN, an acyl-ACP dehydrogenase from Mycobacterium tuberculosis, reveals an unusual acyl-binding pocket

scientific article

A lipid site shapes the agonist response of a pentameric ligand-gated ion channel

scientific article published on 07 October 2019

A tetrameric structure is not essential for activity in dihydrodipicolinate synthase (DHDPS) from Mycobacterium tuberculosis.

scientific article

Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis

scientific article

Anthranilate phosphoribosyltransferase: Binding determinants for 5'-phospho-alpha-d-ribosyl-1'-pyrophosphate (PRPP) and the implications for inhibitor design.

scientific article published on 24 August 2017

Conformational flexibility of EptA driven by an interdomain helix provides insights for enzyme-substrate recognition

scientific article published on 15 July 2021

Corrigendum: Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis

scientific article published on 11 March 2015

Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis

scientific article

Datasets, processing and refinement details for Mtb-AnPRT: inhibitor structures with various space groups

scientific article

Disrupting the quaternary structure of DHDPS as a new approach to antibiotic design. ⬇️

2010 doctoral thesis by Genevieve Laura Evans at University of Canterbury

Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis

scientific article

Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens?

scientific journal article

Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT3 receptor via a common vestibule site

scientific article published on 28 January 2020

Purification, crystallization and preliminary X-ray studies of MbtN (Rv1346) from Mycobacterium tuberculosis

scientific article published on 28 November 2013

Repurposing the chemical scaffold of the anti-arthritic drug Lobenzarit to target tryptophan biosynthesis in Mycobacterium tuberculosis

scientific article

Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex

scientific article

Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding

scientific article

Structures of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Variants Reveal the Conformational Changes That Facilitate Delivery of the Substrate to the Active Site

scientific article

The substrate capture mechanism of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase provides a mode for inhibition

scientific article

Thermodynamics of the fragile X mental retardation protein RGG box interactions with G quartet forming RNA.

scientific article published in July 2006

Paulina is supported by:

About Paulina

Help