List of works - Nicholas Shepherd

A Structural Analysis of DNA Binding by Myelin Transcription Factor 1 Double Zinc Fingers

scientific article

A heterobimetallic Ga/Yb-Schiff base complex for catalytic asymmetric alpha-addition of isocyanides to aldehydes.

scientific article published in June 2009

A peptide affinity reagent for isolating an intact and catalytically active multi-protein complex from mammalian cells.

scientific article published on 22 January 2015

Consecutive Cyclic Pentapeptide Modules Form Shortα-Helices that are Very Stable to Water and Denaturants

scientific article published on 01 May 2004

Constraining cyclic peptides to mimic protein structure motifs.

scientific article

Direct catalytic asymmetric vinylogous Mannich-type and Michael reactions of an alpha,beta-unsaturated gamma-butyrolactam under dinuclear nickel catalysis

scientific article published on 01 March 2010

Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency

scientific article

Engineering specificity changes on a RanBP2 zinc finger that binds single-stranded RNA.

scientific article published on 9 July 2014

Helix-constrained nociceptin peptides are potent agonists and antagonists of ORL-1 and nociception.

scientific article

Insight into the Architecture of the NuRD Complex: STRUCTURE OF THE RbAp48-MTA1 SUBCOMPLEX

scientific article

Left- and right-handed alpha-helical turns in homo- and hetero-chiral helical scaffolds

scientific article published in November 2009

Modular alpha-helical mimetics with antiviral activity against respiratory syncitial virus.

scientific article

Novel Helix-Constrained Nociceptin Derivatives Are Potent Agonists and Antagonists of ERK Phosphorylation and Thermal Analgesia in Mice ⬇️

scientific article published on November 10, 2010

Single turn peptide alpha helices with exceptional stability in water

scientific article

Structural basis for phosphorylation and lysine acetylation cross-talk in a kinase motif associated with myocardial ischemia and cardioprotection

scientific article

Structural basis for phosphorylation and lysine acetylation cross-talk in a kinase motif associated with myocardial ischemia and cardioprotection

scientific article published in Journal of Biological Chemistry

Targeting quorum sensing and competence stimulation for antimicrobial chemotherapy

scientific article

The Identification and Structure of an N-Terminal PR Domain Show that FOG1 Is a Member of the PRDM Family of Proteins

scientific article (publication date: 2014)

The structural basis of DNA binding by the single-stranded DNA-binding protein from Sulfolobus solfataricus

scientific article

List of works by Nicholas Shepherd

A Structural Analysis of DNA Binding by Myelin Transcription Factor 1 Double Zinc Fingers

A heterobimetallic Ga/Yb-Schiff base complex for catalytic asymmetric alpha-addition of isocyanides to aldehydes.

A peptide affinity reagent for isolating an intact and catalytically active multi-protein complex from mammalian cells.

Consecutive Cyclic Pentapeptide Modules Form Shortα-Helices that are Very Stable to Water and Denaturants

Constraining cyclic peptides to mimic protein structure motifs.

Direct catalytic asymmetric vinylogous Mannich-type and Michael reactions of an alpha,beta-unsaturated gamma-butyrolactam under dinuclear nickel catalysis

Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency

Engineering specificity changes on a RanBP2 zinc finger that binds single-stranded RNA.

Helix-constrained nociceptin peptides are potent agonists and antagonists of ORL-1 and nociception.

Insight into the Architecture of the NuRD Complex: STRUCTURE OF THE RbAp48-MTA1 SUBCOMPLEX

Left- and right-handed alpha-helical turns in homo- and hetero-chiral helical scaffolds

Modular alpha-helical mimetics with antiviral activity against respiratory syncitial virus.

Novel Helix-Constrained Nociceptin Derivatives Are Potent Agonists and Antagonists of ERK Phosphorylation and Thermal Analgesia in Mice ⬇️

Single turn peptide alpha helices with exceptional stability in water

Structural basis for phosphorylation and lysine acetylation cross-talk in a kinase motif associated with myocardial ischemia and cardioprotection

Structural basis for phosphorylation and lysine acetylation cross-talk in a kinase motif associated with myocardial ischemia and cardioprotection

Targeting quorum sensing and competence stimulation for antimicrobial chemotherapy

The Identification and Structure of an N-Terminal PR Domain Show that FOG1 Is a Member of the PRDM Family of Proteins

The structural basis of DNA binding by the single-stranded DNA-binding protein from Sulfolobus solfataricus