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List of works by Martino Introna

A human immunodeficiency virus type 1 pol gene-derived sequence (cPPT/CTS) increases the efficiency of transduction of human nondividing monocytes and T lymphocytes by lentiviral vectors

scientific article published in October 2002

A novel method using blinatumomab for efficient, clinical-grade expansion of polyclonal T cells for adoptive immunotherapy

scientific article published on 29 September 2014

A policy for the disposal of autologous hematopoietic progenitor cells: report from an Italian consensus panel

scientific article published on 24 March 2014

A simple and rapid method to analyze specific mRNAs from few cells in a semi-quantitative way using the polymerase chain reaction ⬇️

scientific article published on November 1, 1991

A single point mutation in the v-ets oncogene affects both erythroid and myelomonocytic cell differentiation

scientific article published in December 1988

A-Myb up-regulates Bcl-2 through a Cdx binding site in t(14;18) lymphoma cells.

scientific article

APO B gene polymorphisms and coronary artery disease: a meta-analysis

scientific article

Acquired immunodeficiency syndrome-associated lymphomas are efficiently lysed through complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity by rituximab

scientific article published in December 2002

Autologous mesenchymal stromal cells and kidney transplantation: a pilot study of safety and clinical feasibility.

scientific article

CD20 levels determine the in vitro susceptibility to rituximab and complement of B-cell chronic lymphocytic leukemia: further regulation by CD55 and CD59

scientific article published on 01 December 2001

CD40 ligand-stimulated B cell precursor leukemic cells elicit interferon-gamma production by autologous bone marrow T cells in childhood acute lymphoblastic leukemia

scientific article published on 01 October 2002

CIK as therapeutic agents against tumors

scientific article

Cell-based strategies to manage leukemia relapse: efficacy and feasibility of immunotherapy approaches

scientific article

Characterization of in vitro migratory properties of anti-CD19 chimeric receptor-redirected CIK cells for their potential use in B-ALL immunotherapy

scientific article published in September 2006

Characterization of migratory activity and cytokine profile of helper and cytotoxic CMV-specific T-cell lines expanded by a selective peptide library

scientific article

Characterization of the c-Myb-responsive region and regulation of the human type I collagen alpha 2 chain gene by c-Myb.

scientific article

Chemokines and antagonists in non-Hodgkin's lymphoma

scientific article published on 01 May 2008

Clinical grade expansion of MSCs

scientific article published on 17 June 2015

Cloning and characterization of a new isoform of the interleukin 1 receptor antagonist

scientific article

Complement in antibody therapy: friend or foe?

scientific article published on 01 December 2009

Cytokine Induced Killer (CIK) cells for the treatment of haematological neoplasms.

scientific article published on 29 September 2013

Cytokine-induced killer cells are terminally differentiated activated CD8 cytotoxic T-EMRA lymphocytes.

scientific article published in May 2009

Detection of a transcriptional block in the first intron of the human c-myb gene.

scientific article published on January 1992

Differential response of human acute myeloid leukemia cells to gemtuzumab ozogamicin in vitro: role of Chk1 and Chk2 phosphorylation and caspase 3.

scientific article

Direct involvement of CD56 in cytokine-induced killer-mediated lysis of CD56+ hematopoietic target cells.

scientific article published on 6 September 2014

Direct reprogramming of human bone marrow stromal cells into functional renal cells using cell-free extracts

scientific article

Dual-functional capability of CD3+CD56+ CIK cells, a T-cell subset that acquires NK function and retains TCR-mediated specific cytotoxicity.

scientific article

Effect of a streptococcal preparation (OK432) on natural killer activity of tumour-associated lymphoid cells in human ovarian carcinoma and on lysis of fresh ovarian tumour cells.

scientific article

Endothelial activation by cytokines

scientific article

Endothelial cell regulation of leukocyte infiltration in inflammatory tissues.

scientific article published on January 1995

Enhanced killing of human B-cell lymphoma targets by combined use of cytokine-induced killer cell (CIK) cultures and anti-CD20 antibodies.

scientific article published on 3 November 2010

Evaluation of absorption with Limulus amebocyte lysate to remove contaminating endotoxin from interferon and lymphokine preparations

scientific article published on 01 January 1984

Expression and production of the long pentraxin PTX3 in rheumatoid arthritis (RA)

article

Feasibility and safety of adoptive immunotherapy with CIK cells after cord blood transplantation.

scientific article

Frequent occurrence of non-malignant genetic alterations in clinical grade mesenchymal stromal cells expanded for cell therapy protocols.

scientific article published on 28 March 2014

Givinostat and hydroxyurea synergize in vitro to induce apoptosis of cells from JAK2(V617F) myeloproliferative neoplasm patients.

scientific article

Glycoengineered CD20 antibody obinutuzumab activates neutrophils and mediates phagocytosis through CD16B more efficiently than rituximab

scientific article published on 8 October 2013

Homologous and heterologous desensitization of proto-oncogene cfos expression in murine peritoneal macrophages

article

Human Bone Marrow Mesenchymal Stem Cells Accelerate Recovery of Acute Renal Injury and Prolong Survival in Mice

scholarly article by Marina Morigi et al published August 2008 in Stem Cells

Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function

scientific article

Human neutrophils express low levels of FcγRIIIA, which plays a role in PMN activation

scientific article published on 17 January 2019

Human neutrophils mediate trogocytosis rather than phagocytosis of CLL B cells opsonized with anti-CD20 antibodies

scientific article

Ibrutinib interferes with the cell-mediated anti-tumor activities of therapeutic CD20 antibodies: implications for combination therapy

scientific article

Identification of two novel isoforms of the ZNF162 gene: a growing family of signal transduction and activator of RNA proteins

scientific article (publication date: June 1997)

Inducible expression of the long pentraxin PTX3 in the central nervous system.

scientific article

Induction of cytotoxicity by interleukin-2 in T gamma-lymphoproliferative disorders.

scientific article published in January 1986

Inhibition of Monocyte Chemotaxis to C-C Chemokines by Antisense Oligonucleotide for Cytosolic Phospholipase A

scientific article published in Journal of Biological Chemistry

Interleukin-1 and Tumor Necrosis Factor Induce Transient Expression of an Inhibitor of Nuclear Factor kB in Endothelial Cells

Intraperitoneal administration ofcorynebacterium parvum in patients with ascitic ovarian tumors resistant to chemotherapy: Effects on cytotoxicity of tumor-associated macrophages and NK cells

scientific article published on 01 January 1981

Kidney transplant tolerance associated with remote autologous mesenchymal stromal cell administration

scientific article published on 24 December 2019

Kinetics of the use of cryopreserved autologous stem cell grafts: a GITMO-SIDEM survey.

scientific article published on 26 October 2013

Large granular lymphocyte/natural killer cell proliferative disease: clinical and laboratory heterogeneity

scientific article published on 01 August 1986

Life-sparing effect of human cord blood-mesenchymal stem cells in experimental acute kidney injury

scientific article

Localization of Mesenchymal Stromal Cells Dictates Their Immune or Proinflammatory Effects in Kidney Transplantation

scientific article published on 29 May 2012

Long-Term Clinical and Immunological Profile of Kidney Transplant Patients Given Mesenchymal Stromal Cell Immunotherapy.

scientific article

Longitudinal tracking of triple labeled umbilical cord derived mesenchymal stromal cells in a mouse model of Amyotrophic Lateral Sclerosis

scientific article published on 27 June 2015

Lymphokine production in T gamma lymphoproliferative disorders.

scientific article

M2 macrophages phagocytose rituximab-opsonized leukemic targets more efficiently than m1 cells in vitro.

scientific article published on April 2009

Mechanism of action of type II, glycoengineered, anti-CD20 monoclonal antibody GA101 in B-chronic lymphocytic leukemia whole blood assays in comparison with rituximab and alemtuzumab.

scientific article published on 4 February 2011

Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Fourth Meeting: lessons learned from first clinical trials.

scientific article published on August 2013

Mesenchymal stromal cells and kidney transplantation: pretransplant infusion protects from graft dysfunction while fostering immunoregulation.

scientific article published on 6 June 2013

Mesenchymal stromal cells do not increase the risk of viral reactivation nor the severity of viral events in recipients of allogeneic stem cell transplantation

scientific article

Mesenchymal stromal cells for prevention and treatment of graft-versus-host disease: successes and hurdles

scientific article published on February 2015

Mesenchymal stromal cells for the treatment of graft-versus-host disease: understanding the in vivo biological effect through patient immune monitoring

scientific article published on 13 January 2012

Migratory Response of Human NK Cells to Monocyte-Chemotactic Proteins

article

Minimally manipulated whole human umbilical cord is a rich source of clinical-grade human mesenchymal stromal cells expanded in human platelet lysate

scientific article published on 18 March 2011

Modulation of cell cycle by graded expression of MLL-AF4 fusion oncoprotein

scientific article (publication date: June 2004)

Molecular events underlying interleukin-6 independence in a subclone of the CMA-03 multiple myeloma cell line

scientific article published on 5 November 2013

Molecular evidence of inefficient transduction of proliferating human B lymphocytes by VSV-pseudotyped HIV-1-derived lentivectors

scientific article published in August 2004

Multimer formation and ligand recognition by the long pentraxin PTX3. Similarities and differences with the short pentraxins C-reactive protein and serum amyloid P component.

scientific article published in December 1997

Mutations in v-myb alter the differentiation of myelomonocytic cells transformed by the oncogene.

scientific article published in December 1990

Ofatumumab is more efficient than rituximab in lysing B chronic lymphocytic leukemia cells in whole blood and in combination with chemotherapy.

scientific article published on 5 December 2012

Phase II Study of Sequential Infusion of Donor Lymphocyte Infusion and Cytokine-Induced Killer Cells for Patients Relapsed after Allogeneic Hematopoietic Stem Cell Transplantation.

scientific article published on 13 July 2017

Phenotypical and Functional Characteristics of In Vitro-Expanded Adipose-Derived Mesenchymal Stromal Cells From Patients With Systematic Sclerosis

scientific article published on 31 January 2017

Platelet-lysate-Expanded Mesenchymal Stromal Cells as a Salvage Therapy for Severe Resistant Graft-versus-Host Disease in a Pediatric Population

scientific article published on 27 March 2010

Pleiotropic anti-myeloma activity of ITF2357: inhibition of interleukin-6 receptor signaling and repression of miR-19a and miR-19b

scientific article

Possible misinterpretation of the mode of action of therapeutic antibodies in vitro: homotypic adhesion and flow cytometry result in artefactual direct cell death

scientific article published on 01 October 2010

Preventive administration of Mycobacterium tuberculosis 10-kDa heat shock protein (hsp10) suppresses adjuvant arthritis in Lewis rats

scientific article published on 01 March 2002

Rapid retroviral infection of human haemopoietic cells of different lineages: efficient transfer in fresh T cells.

scientific article published on November 1998

Regulation of endothelial cell function by pro- and anti-inflammatory cytokines

scientific article published on 01 December 1998

Regulation of inhibitory pathways of the interleukin-1 system

scientific article published in May 1998

Repeated infusions of donor-derived cytokine-induced killer cells in patients relapsing after allogeneic stem cell transplantation: a phase I study

scientific article published in July 2007

Safety of retroviral gene marking with a truncated NGF receptor

scientific article published on 01 April 2003

Small dose of rituximab for graves orbitopathy: new insights into the mechanism of action

scientific article published on 01 January 2012

Suicide gene therapy and the control of graft-vs-host disease

scientific article published in September 2004

Synergism between fludarabine and rituximab revealed in a follicular lymphoma cell line resistant to the cytotoxic activity of either drug alone.

scientific article

The DNA Binding Domain of the A-MYB Transcription Factor Is Responsible for Its B Cell-specific Activity and Binds to a B Cell 110-kDa Nuclear Protein ⬇️

scientific article published on October 3, 1997

The HDAC inhibitor Givinostat modulates the hematopoietic transcription factors NFE2 and C-MYB in JAK2(V617F) myeloproliferative neoplasm cells

scientific article published on 8 May 2012

The Polo-Like Kinase 1 (PLK1) inhibitor NMS-P937 is effective in a new model of disseminated primary CD56+ acute monoblastic leukaemia

scientific article

The washouts of discarded bone marrow collection bags and filters are a very abundant source of hMSCs.

scientific article

Therapeutic efficacy of the pan-cdk inhibitor PHA-793887 in vitro and in vivo in engraftment and high-burden leukemia models.

scientific article

Therapeutic potential of stromal cells of non-renal or renal origin in experimental chronic kidney disease

scholarly article by Cinzia Rota et al published 14 August 2018 in Stem Cell Research & Therapy

Thrombospondin-1 promotes mesenchymal stromal cell functions via TGFβ and in cooperation with PDGF.

scientific article published on 15 March 2016

Toward MSC in Solid Organ Transplantation: 2008 Position Paper of the MISOT Study Group

article

Transfer of growth factor receptor mRNA via exosomes unravels the regenerative effect of mesenchymal stem cells

scientific article

Transplanted Umbilical Cord Mesenchymal Stem Cells Modify the In Vivo Microenvironment Enhancing Angiogenesis and Leading to Bone Regeneration

scientific article published on 18 March 2015

Treatment of graft versus host disease with mesenchymal stromal cells: a phase I study on 40 adult and pediatric patients

scientific article published on 7 December 2013

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