Search filters

List of works by Merja Heinäniemi

Aggravated Postinfarct Heart Failure in Type 2 Diabetes Is Associated with Impaired Mitophagy and Exaggerated Inflammasome Activation.

scientific article published on 18 September 2017

Agonist-dependent and agonist-independent transactivations of the human constitutive androstane receptor are modulated by specific amino acid pairs

scientific article

Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture.

scientific article published on 3 October 2017

Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture.

scientific article published in September 2017

Combinatorial regulation of lipoprotein lipase by microRNAs during mouse adipogenesis.

scientific article published on 16 January 2014

Comprehensive analysis of PPARalpha-dependent regulation of hepatic lipid metabolism by expression profiling

scientific article

Controlling the chromatin organization of vitamin D target genes by multiple vitamin D receptor binding sites

scientific article published on 16 January 2007

Coordinate induction of PPAR alpha and SREBP2 in multifunctional protein 2 deficient mice

scientific article

Cyclical regulation of the insulin-like growth factor binding protein 3 gene in response to 1alpha,25-dihydroxyvitamin D3.

scientific article published on 19 September 2010

DICKKOPF-4 is induced by TCF/beta-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1alpha,25-dihydroxyvitamin D3.

scientific article

Data-driven characterization of molecular phenotypes across heterogeneous sample collections ⬇️

scientific article published on 01 July 2019

Dataset integration identifies transcriptional regulation of microRNA genes by PPARγ in differentiating mouse 3T3-L1 adipocytes

scientific article

Derailed regulatory network in childhood acute leukaemia

scientific article published in March 2017

Deregulation of the non-coding genome in leukemia

scientific article published on 7 April 2017

Endothelial cell differentiation is encompassed by changes in long range interactions between inactive chromatin regions.

scientific article published on 4 December 2017

Gene-pair expression signatures reveal lineage control

scientific article

Genome-wide repression of eRNA and target gene loci by the ETV6-RUNX1 fusion in acute leukemia

scientific article published on 12 September 2016

HOXA9 cooperates with activated JAK/STAT signaling to drive leukemia development.

scientific article published in March 2018

Hemap: An Interactive Online Resource for Characterizing Molecular Phenotypes across Hematologic Malignancies

scientific article published on 02 April 2019

Identification of pregnane X receptor binding sites in the regulatory regions of genes involved in bile acid homeostasis.

scientific article published on 5 January 2005

In silico and preclinical drug screening identifies dasatinib as a targeted therapy for T-ALL.

scientific article published on 8 September 2017

Integrated analysis of transcript-level regulation of metabolism reveals disease-relevant nodes of the human metabolic network

scientific article

Integrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network

scientific article

Meta-analysis of primary target genes of peroxisome proliferator-activated receptors

scientific article

Novel insights into the regulation of antioxidant-response-elementmediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2

article

Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma

scientific article published on 23 August 2019

Overexpression of PTP4A3 in ETV6-RUNX1 acute lymphoblastic leukemia.

scientific article published on 26 December 2016

Overexpression of SNORD114-3 marks acute promyelocytic leukemia

scientific article published on 27 August 2013

Peroxisome proliferator-activated receptor-γ coactivator 1 α1 induces a cardiac excitation-contraction coupling phenotype without metabolic remodelling

scientific article published on 26 September 2016

Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia

scientific article published on 11 July 2019

Profiling of promoter occupancy by PPARalpha in human hepatoma cells via ChIP-chip analysis

scientific article published on 27 January 2010

Role of the Keap1-Nrf2 pathway in cancer

scientific article published on January 2014

SIX6 is a TAL1-regulated transcription factor in T-ALL and associated with inferior outcome

scientific article published on 24 August 2020

Screening for PPAR Responsive Regulatory Modules in Cancer.

scientific article published on January 2008

Signalling input from divergent pathways subverts B cell transformation

scientific article published on 22 July 2020

Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1-positive pediatric leukemia identifies drug-targetable transcription factor activities

scientific article published on 20 November 2020

Systems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson's disease

scientific article

The Effects of Sequence Variation on Genome-wide NRF2 Binding--New Target Genes and Regulatory SNPs

scientific article

The Impact of Whole GenomeIn SilicoScreening for Nuclear Receptor-Binding Sites in Systems Biology

Time-resolved expression profiling of the nuclear receptor superfamily in human adipogenesis

scientific article

Transcription-coupled genetic instability marks acute lymphoblastic leukemia structural variation hotspots

scientific article published on 19 July 2016

Paulina is supported by:

About Paulina

Help