List of works - Lukas Simon

A cellular census of human lungs identifies novel cell states in health and in asthma

scientific article published on 17 June 2019

A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection

scientific article published on 09 January 2017

An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics

scientific article published on 27 February 2019

CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT

scientific article

Common variants in the human platelet PAR4 thrombin receptor alter platelet function and differ by race

scientific article

EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells

scientific article

Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics.

scientific article

IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling

scientific article published in Nature Communications

Identification of a functional genetic variant driving racially dimorphic platelet gene expression of the thrombin receptor regulator, PCTP.

scientific article published on 2 March 2017

Integrative Multi-omic Analysis of Human Platelet eQTLs Reveals Alternative Start Site in Mitofusin 2.

scientific article published on 26 April 2016

MetaMap, an interactive webtool for the exploration of metatranscriptomic reads in human disease-related RNA-seq data

scholarly article published 30 September 2018

MetaMap: An atlas of metatranscriptomic reads in human disease-related RNA-seq data

scholarly article published 22 February 2018

MetaMap: an atlas of metatranscriptomic reads in human disease-related RNA-seq data.

scientific article published in June 2018

PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells

scientific article published on 19 March 2019

Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c

scientific article

SNP in human ARHGEF3 promoter is associated with DNase hypersensitivity, transcript level and platelet function, and Arhgef3 KO mice have increased mean platelet volume

scientific article

Single-cell RNA-seq denoising using a deep count autoencoder

scientific article published in Nature Communications

The spliceosome is a therapeutic vulnerability in MYC-driven cancer

scientific article

List of works by Lukas Simon

A cellular census of human lungs identifies novel cell states in health and in asthma

A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection

An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics

CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT

Common variants in the human platelet PAR4 thrombin receptor alter platelet function and differ by race

EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells

Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics.

IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling

Identification of a functional genetic variant driving racially dimorphic platelet gene expression of the thrombin receptor regulator, PCTP.

Integrative Multi-omic Analysis of Human Platelet eQTLs Reveals Alternative Start Site in Mitofusin 2.

MetaMap, an interactive webtool for the exploration of metatranscriptomic reads in human disease-related RNA-seq data

MetaMap: An atlas of metatranscriptomic reads in human disease-related RNA-seq data

MetaMap: an atlas of metatranscriptomic reads in human disease-related RNA-seq data.

PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells

Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c

SNP in human ARHGEF3 promoter is associated with DNase hypersensitivity, transcript level and platelet function, and Arhgef3 KO mice have increased mean platelet volume

Single-cell RNA-seq denoising using a deep count autoencoder

The spliceosome is a therapeutic vulnerability in MYC-driven cancer