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List of works by Alistair Mathie

5-HT3 receptor channels in dissociated rat superior cervical ganglion neurons

scientific article published on 01 March 1992

A "Target Class" Screen to Identify Activators of Two-Pore Domain Potassium (K2P) Channels

scientific article published on 29 December 2020

A non-inactivating K+ current sensitive to muscarinic receptor activation in rat cultured cerebellar granule neurons.

scientific article published in March 1996

Acetylcholine receptor channels and their block by clonidine in cultured bovine chromaffin cells

scientific article published on 01 August 1988

Activation of TREK currents by riluzole in three subgroups of cultured mouse nodose ganglion neurons.

scientific article

Activation of glutamate receptors and glutamate uptake in identified macroglial cells in rat cerebellar cultures.

scientific article published in January 1991

Activation of group I metabotropic glutamate receptors elicits pH changes in cultured rat cortical glia and neurons

scientific article

Alpha-adrenoceptors and facilitation at a sympathetic neuroeffector junction

scientific article published on 01 March 1984

Aristolochic acid, a plant extract used in the treatment of pain and linked to Balkan endemic nephropathy, is a regulator of K2P channels

scientific article published on 23 February 2016

Background potassium channels move into focus

scientific article

Characterisation and regulation of wild type and mutant TASK-1 two pore domain potassium channels indicated in pulmonary arterial hypertension

scientific article published on 24 November 2018

Characterization of muscarinic receptor subtypes inhibiting Ca2+ current and M current in rat sympathetic neurons

scientific article published on October 1992

Characterization of the hyperpolarization-activated chloride current in dissociated rat sympathetic neurons

scientific article published in February 1998

Conductance and kinetic properties of single nicotinic acetylcholine receptor channels in rat sympathetic neurones

scientific article published in August 1991

Dominant negative effects of a non-conducting TREK1 splice variant expressed in brain.

scientific article

Effects of the ventilatory stimulant, doxapram on human TASK-3 (KCNK9, K2P9.1) channels and TASK-1 (KCNK3, K2P3.1) channels

scientific article published on 18 September 2019

Enhanced inflammatory cell profiles in schistosomiasis-induced pulmonary vascular remodeling

scientific article

Enhancement of TWIK-related acid-sensitive potassium channel 3 (TASK3) two-pore domain potassium channel activity by tumor necrosis factor α.

scientific article published on 4 December 2013

Facilitation at single release sites of a sympathetic neuroeffector junction in the mouse

scientific article published on 01 April 1984

G(alpha)q-mediated regulation of TASK3 two-pore domain potassium channels: the role of protein kinase C

scientific article published on 20 March 2007

GI-530159, a novel, selective, mechanosensitive two-pore-domain potassium (K2P ) channel opener, reduces rat dorsal root ganglion neuron excitability.

scientific article published on 18 November 2017

Gain and loss of TASK3 channel function and its regulation by novel variation cause KCNK9 imprinting syndrome

scientific article published on 13 June 2022

Gating of two pore domain potassium channels.

scientific article published on 21 June 2010

Guide to Receptors and Channels (GRAC), 3rd edition

scientific article published in March 2008

Guide to Receptors and Channels (GRAC), 5th edition

scientific article

Guide to receptors and channels, 1st edition (2005 revision).

scientific article published in March 2005

Guide to receptors and channels, 1st edition.

scientific article published on March 2004

Guide to receptors and channels, 2nd edition

scientific article published in March 2006

GuideToPharmacology.org--an update

scientific article

HIV transgene expression impairs K+ channel function in the pulmonary vasculature

Identification of a region in the TASK3 two pore domain potassium channel that is critical for its blockade by methanandamide.

scientific article published on 10 September 2007

Influence of the N terminus on the biophysical properties and pharmacology of TREK1 potassium channels

scientific article published on 07 February 2014

Inhibition by inorganic ions of a sustained calcium signal evoked by activation of mGlu5 receptors in rat cortical neurons and glia

scientific article published in December 1998

Inhibition of N- and L-type calcium channels by muscarinic receptor activation in rat sympathetic neurons

scientific article published on 01 May 1992

Inhibition of delayed rectifier K+ conductance in cultured rat cerebellar granule neurons by activation of calcium-permeable AMPA receptors

scientific article published on 01 March 2000

Inhibition of neuronal KV potassium currents by the antidepressant drug, fluoxetine

scientific article

Inhibition of the human two-pore domain potassium channel, TREK-1, by fluoxetine and its metabolite norfluoxetine

scientific article

Inhibition of the potassium current IK(SO), in cerebellar granule cells, by the inhibitors of MEK1 activation, PD 98059 and U 0126

scientific article published on 01 February 2002

Interactions between the effects of yohimbine, clonidine and [Ca]o on the electrical response of the mouse vas deferens

scientific article published on August 1986

Intracellular Ca2+ buffers disrupt muscarinic suppression of Ca2+ current and M current in rat sympathetic neurons.

scientific article published on January 1991

Ion channels activated by acetylcholine and γ-aminobutyric acid in freshly dissociated sympathetic neurones of the rat

scientific article published on 01 May 1986

Ion channels as novel therapeutic targets in the treatment of pain

scientific article published on September 2010

Is EAG the answer to the M-current?

scientific article published on January 1997

Modifying the subunit composition of TASK channels alters the modulation of a leak conductance in cerebellar granule neurons.

scientific article published in December 2005

Modulation of the gating of the transient outward potassium current of rat isolated cerebellar granule neurons by lanthanum

scientific article published on 01 October 1994

Multiple G-protein-coupled pathways inhibit N-type Ca channels of neurons.

scientific article

Neuronal ion channels and their sensitivity to extremely low frequency weak electric field effects.

scientific article published on January 2003

Neuronal two-pore-domain potassium channels and their regulation by G protein-coupled receptors

scientific article published on 26 October 2006

Opportunistic screening for atrial fibrillation by clinical pharmacists in UK general practice during the influenza vaccination season: A cross-sectional feasibility study

scientific article published on 17 July 2020

Pharmacists detecting atrial fibrillation (PDAF) in primary care during the influenza vaccination season: a multisite, cross-sectional screening protocol.

scientific article

Pharmacological characterization of a non-inactivating outward current observed in mouse cerebellar Purkinje neurones

scientific article published on February 2002

Pharmacologically reversible, loss of function mutations in the TM2 and TM4 inner pore helices of TREK-1 K2P channels

scientific article published on 27 August 2019

Pranlukast is a novel small molecule activator of the two-pore domain potassium channel TREK2

scientific article published on 26 September 2019

Purinergic and muscarinic receptor activation activates a common calcium entry pathway in rat neocortical neurons and glial cells

scientific article published on 01 July 2000

Recovery of current through mutated TASK3 potassium channels underlying Birk Barel syndrome

scientific article published on 16 December 2013

Rectification of currents activated by nicotinic acetylcholine receptors in rat sympathetic ganglion neurones

scientific article published in August 1990

Selective block of the human 2-P domain potassium channel, TASK-3, and the native leak potassium current, IKSO, by zinc

scientific article

Single-channel and whole-cell currents evoked by acetylcholine in dissociated sympathetic neurons of the rat.

scientific article

TASK-1 (KCNK3) channels in the lung: from cell biology to clinical implications.

scientific article published on 9 November 2017

TASK-3 two-pore domain potassium channels enable sustained high-frequency firing in cerebellar granule neurons

scientific article

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Catalytic receptors

scientific article published on 01 December 2019

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes

scientific article published on 01 December 2019

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein-coupled receptors

scientific article published on 01 December 2019

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Introduction and Other Protein Targets

scientific article published on 01 December 2019

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels

scientific article published on 01 December 2019

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Nuclear hormone receptors

scientific article published on 01 December 2019

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Transporters

scientific article published on 01 December 2019

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors

journal article from 'British Journal of Pharmacology' published in 2021

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Nuclear hormone receptors

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters

TRESK is a key regulator of nocturnal suprachiasmatic nucleus dynamics and light adaptive responses

scientific article published on 14 September 2020

Terbinafine is a novel and selective activator of the two-pore domain potassium channel TASK3.

scientific article

The M1P1 loop of TASK3 K2P channels apposes the selectivity filter and influences channel function.

scientific article published on 16 April 2008

The in vivo contributions of TASK-1-containing channels to the actions of inhalation anesthetics, the alpha(2) adrenergic sedative dexmedetomidine, and cannabinoid agonists.

scientific article published on 5 January 2006

The role of Ca2+ stores in the muscarinic inhibition of the K+ current IK(SO) in neonatal rat cerebellar granule cells

scientific article published on 01 December 2000

The two-pore-domain K(+) channels TREK-1 and TASK-3 are differentially modulated by copper and zinc

scientific article published in September 2004

Trafficking of Neuronal Two Pore Domain Potassium Channels

scientific article published on September 1, 2010

Two-Pore Domain Potassium Channels as Drug Targets: Anesthesia and Beyond

scientific article published on 17 July 2020

Two-pore domain potassium channels: potential therapeutic targets for the treatment of pain

scientific article

Two-pore-domain K+ channels are a novel target for the anesthetic gases xenon, nitrous oxide, and cyclopropane

scientific article

Voltage-activated potassium channels in mammalian neurons and their block by novel pharmacological agents.

scientific article published on January 1998

What are the roles of the many different types of potassium channel expressed in cerebellar granule cells?

scientific article

Zinc and copper: pharmacological probes and endogenous modulators of neuronal excitability.

scientific article