List of works by Giovanna Lattanzi

108th ENMC International Workshop, 3rd Workshop of the MYO-CLUSTER project: EUROMEN, 7th International Emery-Dreifuss Muscular Dystrophy (EDMD) Workshop, 13-15 September 2002, Naarden, The Netherlands

scientific article

A novel phenotypic expression associated with a new mutation in LMNA gene, characterized by partial lipodystrophy, insulin resistance, aortic stenosis and hypertrophic cardiomyopathy

scientific article published on July 2008

A pathogenic mechanism leading to partial lipodistrophy and prospects for pharmacological treatment of insulin resistance syndrome

scientific article published on 01 January 2007

A-type lamins and signaling: the PI 3-kinase/Akt pathway moves forward

scientific article published on September 2009

All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype.

scientific article published on 13 August 2015

Alterations of nuclear envelope and chromatin organization in mandibuloacral dysplasia, a rare form of laminopathy

scientific article published on 26 July 2005

Altered adipocyte differentiation and unbalanced autophagy in type 2 Familial Partial Lipodystrophy: an in vitro and in vivo study of adipose tissue browning

scientific article published on 02 August 2019

Altered chromatin organization and SUN2 localization in mandibuloacral dysplasia are rescued by drug treatment.

scientific article

Altered modulation of lamin A/C-HDAC2 interaction and p21 expression during oxidative stress response in HGPS

scientific article published on 15 August 2018

Altered pre-lamin A processing is a common mechanism leading to lipodystrophy.

scientific article published on 20 April 2005

An overview of new translational, clinical and therapeutic perspectives in laminopathies and other nuclear envelope-related diseases.

scientific article published on 11 November 2015

Ankrd2 in Mechanotransduction and Oxidative Stress Response in Skeletal Muscle: New Cues for the Pathogenesis of Muscular Laminopathies

scientific article published on 24 July 2019

Ankrd2/ARPP is a novel Akt2 specific substrate and regulates myogenic differentiation upon cellular exposure to H(2)O(2)

scientific article

Association of emerin with nuclear and cytoplasmic actin is regulated in differentiating myoblasts

scientific article (publication date: 11 April 2003)

At the nucleus of the problem: nuclear proteins and disease

scientific article

Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria.

scientific article published on 19 October 2011

BK channel overexpression on plasma membrane of fibroblasts from Hutchinson-Gilford progeria syndrome

scientific article published on 01 November 2018

Barrier-to-autointegration factor (BAF) involvement in prelamin A-related chromatin organization changes

scientific article published on 20 December 2015

Bethlem myopathy (BETHLEM) 86th ENMC international workshop, 10-11 November 2000, Naarden, The Netherlands.

scientific article published in March 2002

Bethlem myopathy (BETHLEM) and Ullrich scleroatonic muscular dystrophy: 100th ENMC international workshop, 23-24 November 2001, Naarden, The Netherlands

scientific article published in December 2002

Binding of hexachloroethane to biological macromolecules from rat and mouse organs

scientific article published on 01 January 1988

CD99 acts as an oncosuppressor in osteosarcoma

scientific article

Cardiolaminopathies from bench to bedside: challenges in clinical decision-making with focus on arrhythmia-related outcomes

scientific article published in January 2018

Changes in polyphosphoinositide levels in rat liver nuclei in response to prolactin, a known hepatic mitogen

scientific article published on 01 July 1992

Chloroform Bioactivation Leading to Nucleic Acids Binding ⬇️

scientific article published on August 31, 1991

Chromatin dynamics and in vitro biomarkers in laminopathies: an overview.

scientific article published on 11 November 2015

Collagen VI deficiency affects the organization of fibronectin in the extracellular matrix of cultured fibroblasts

article

Compound Heterozygosity for Mutations inLMNAin a Patient with a Myopathic and Lipodystrophic Mandibuloacral Dysplasia Type A Phenotype

scientific article published on 11 September 2007

Constitutive heterochromatin: a surprising variety of expressed sequences.

scientific article published on 02 May 2009

Covalent binding of 1,1,1,2‐tetrachloroethane to nucleic acids as evidence of genotoxic activity

scientific article published on 01 January 1989

Cytokine Profile in Striated Muscle Laminopathies: New Promising Biomarkers for Disease Prediction

scientific article published on 23 June 2020

Detection of mesenchymal stem cells senescence by prelamin A accumulation at the nuclear level.

scientific article published on 26 August 2016

Different prelamin A forms accumulate in human fibroblasts: a study in experimental models and progeria.

scientific article published on 31 March 2009

Different prelamin A forms accumulate in human fibroblasts: a study in experimental models and progeria.

scientific article published in January 2009

Diverse lamin-dependent mechanisms interact to control chromatin dynamics. Focus on laminopathies

scientific article

Doubly heterozygous LMNA and TTN mutations revealed by exome sequencing in a severe form of dilated cardiomyopathy

scientific article published on 06 March 2013

Drugs affecting prelamin A processing: effects on heterochromatin organization

scientific article

Dysferlin in a hyperCKaemic patient with caveolin 3 mutation and in C2C12 cells after p38 MAP kinase inhibition

scientific article (publication date: 31 December 2003)

Ectopic Expression of Ankrd2 Affects Proliferation, Motility and Clonogenic Potential of Human Osteosarcoma Cells

scientific article published on 06 January 2021

Effects of prelamin A processing inhibitors on the differentiation and activity of human osteoclasts

scientific article published in September 2008

Elevated TGF β2 serum levels in Emery-Dreifuss muscular dystrophy: implications for myocyte and tenocyte differentiation and fibrogenic processes.

scientific article

Emerging perspectives on laminopathies

Emerin Phosphorylation during the Early Phase of the Oxidative Stress Response Influences Emerin-BAF Interaction and BAF Nuclear Localization

scientific article published on 06 June 2020

Emerin increase in regenerating muscle fibers

article

Emerin-prelamin A interplay in human fibroblasts

scientific article

Emery-Dreifuss Muscular Dystrophy-Associated Mutant Forms of Lamin A Recruit the Stress Responsive Protein Ankrd2 into the Nucleus, Affecting the Cellular Response to Oxidative Stress.

scientific article published on 25 May 2017

Emery-Dreifuss muscular dystrophy, nuclear cell signaling and chromatin remodeling

scientific article

Extracellular matrix and nuclear abnormalities in skeletal muscle of a patient with Walker-Warburg syndrome caused by POMT1 mutation

scientific article

Failure of lamin A/C to functionally assemble in R482L mutated familial partial lipodystrophy fibroblasts: altered intermolecular interaction with emerin and implications for gene transcription

scientific article published in November 2003

Familial partial lipodystrophy, mandibuloacral dysplasia and restrictive dermopathy feature barrier-to-autointegration factor (BAF) nuclear redistribution

scientific article

Functional domains of the nucleus: implications for Emery-Dreifuss muscular dystrophy

scientific article

Genotoxic and biochemical effects of dimethylamine

scientific article published on 01 May 1993

High resolution detection of uncoated metaphase chromosomes by means of field emission scanning electron microscopy

scientific article published on 01 October 1994

High-resolution FEISEM detection of DNA centromeric probes in HeLa metaphase chromosomes

scientific article published on April 1995

Immunocytochemistry of nuclear domains and Emery-Dreifuss muscular dystrophy pathophysiology.

scientific article

Implications for nuclear organization and gene transcription of lamin A/C specific mutations

article

Improvement of short-term tests for mutagenicity: on the optimal pH for the liver microsomal assay

scientific article published on 01 December 1988

In vivo and in vitro interaction of trichloroethylene with macromolecules from various organs of rat and mouse.

scientific article published in May 1992

Interleukin-6 neutralization ameliorates symptoms in prematurely aged mice

scientific article published on 03 January 2021

LMNA-associated myopathies: the Italian experience in a large cohort of patients.

scientific article published on October 2014

Lamin A Ser404 is a nuclear target of Akt phosphorylation in C2C12 cells

scientific article published on 23 September 2008

Lamin A and Prelamin A Counteract Migration of Osteosarcoma Cells

scientific article published on 22 March 2020

Lamin A precursor induces barrier-to-autointegration factor nuclear localization.

scientific article published in July 2010

Laminopathies

scientific article published on 01 January 2018

Laminopathies and A-type lamin-associated signalling pathways.

scientific article

Laminopathies and lamin-associated signaling pathways

scientific article

Laminopathies: a chromatin affair

scientific article published on 18 July 2006

Laminopathies: involvement of structural nuclear proteins in the pathogenesis of an increasing number of human diseases

scientific article published in May 2005

Laminopathies: many diseases, one gene. Report of the first Italian Meeting Course on Laminopathies.

scientific article published on October 2011

Lamins and bone disorders: current understanding and perspectives.

scientific article

Lamins are rapamycin targets that impact human longevity: a study in centenarians

scientific article published on 23 October 2013

Linkage of lamins to fidelity of gene transcription

scientific article

Mandibuloacral dysplasia: A premature ageing disease with aspects of physiological ageing

scientific article published on 2 December 2017

Modulation of TGFbeta 2 levels by lamin A in U2-OS osteoblast-like cells: understanding the osteolytic process triggered by altered lamins

scientific article

Molecular mechanisms of CD99-induced caspase-independent cell death and cell-cell adhesion in Ewing's sarcoma cells: actin and zyxin as key intracellular mediators.

scientific article

Morphological study of TNPO3 and SRSF1 interaction during myogenesis by combining confocal, structured illumination and electron microscopy analysis

scientific article published on 15 January 2021

Muscular dystrophy-associated SUN1 and SUN2 variants disrupt nuclear-cytoskeletal connections and myonuclear organization

scientific article (publication date: September 2014)

Muscular laminopathies: role of prelamin A in early steps of muscle differentiation

scientific article published on 28 October 2010

Network assessment of demethylation treatment in melanoma: Differential transcriptome-methylome and antigen profile signatures

scientific article published in PLoS ONE

Novel COL6A1 splicing mutation in a family affected by mild Bethlem myopathy

scientific article published on 01 April 2002

Novel histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in sarcoma cancer stem cells

scientific article published on 30 April 2015

Nuclear alterations in autosomal-dominant Emery-Dreifuss muscular dystrophy

article published in 2001

Nuclear damages and oxidative stress: new perspectives for laminopathies

scientific article published on 18 October 2012

Nuclear envelope proteins and chromatin arrangement: a pathogenic mechanism for laminopathies.

scientific article

O-4The Italian Network for Laminopathies.

scientific article published in October 2011

Oct-1 recruitment to the nuclear envelope in adult-onset autosomal dominant leukodystrophy

scientific article published on 20 December 2012

Osteoblasts from a mandibuloacral dysplasia patient induce human blood precursors to differentiate into active osteoclasts

scientific article published on 16 March 2011

PCAF Involvement in Lamin A/C-HDAC2 Interplay during the Early Phase of Muscle Differentiation

scientific article published on 20 July 2020

Partial lipodystrophy associated with muscular dystrophy of unknown genetic origin

scientific article published on 01 June 2014

Potential therapeutic effects of the MTOR inhibitors for preventing ageing and progeria-related disorders

scientific article

Pre-Lamin A processing is linked to heterochromatin organization.

scientific article published in December 2007

Prelamin A is involved in early steps of muscle differentiation.

scientific article

Prelamin A processing and heterochromatin dynamics in laminopathies.

scientific article published on 23 December 2006

Prelamin A-mediated nuclear envelope dynamics in normal and laminopathic cells

scientific article published on December 2011

Prelamin A-mediated recruitment of SUN1 to the nuclear envelope directs nuclear positioning in human muscle.

scientific article published on 11 February 2011

Prevalent cardiac phenotype resulting in heart transplantation in a novel LMNA gene duplication

scientific article

Progeroid laminopathy with restrictive dermopathy-like features caused by an isodisomic LMNA mutation p.R435C.

scientific article published on June 2013

Rapamycin treatment of Mandibuloacral dysplasia cells rescues localization of chromatin-associated proteins and cell cycle dynamics

scientific article

Reduced adipogenic gene expression in fibroblasts from a patient with type 2 congenital generalized lipodystrophy.

scientific article published on October 2010

Remodelling of the nuclear lamina during human cytomegalovirus infection: role of the viral proteins pUL50 and pUL53

scientific article published on 01 March 2008

Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment

scientific article published on November 2005

SREBP1 interaction with prelamin A forms: a pathogenic mechanism for lipodystrophic laminopathies

scientific article published on 19 November 2007

Samp1 Mislocalization in Emery-Dreifuss Muscular Dystrophy

scientific article published on 15 October 2018

Satellite cell characterization from aging human muscle.

scientific article

Short-term tests of genotoxicity for 1,1,1-trichloroethane

scientific article published in June 1986

Silencing of Euchromatic Transposable Elements as a Consequence of Nuclear Lamina Dysfunction

scientific article published on 05 March 2020

Site-dependent differences in both prelamin A and adipogenic genes in subcutaneous adipose tissue of patients with type 2 familial partial lipodystrophy

article

Slug transcription factor and nuclear Lamin B1 are upregulated in osteoarthritic chondrocytes

scientific article published on 20 March 2015

Statins and Histone Deacetylase Inhibitors Affect Lamin A/C - Histone Deacetylase 2 Interaction in Human Cells

scientific article published on 31 January 2019

Staurosporine treatment and serum starvation promote the cleavage of emerin in cultured mouse myoblasts: involvement of a caspase-dependent mechanism

scientific article

Strategies for optimization of short-term genotoxicity tests: the synergistic effect of NADPH and NADH on P450 function in processing pre mutagens

scientific article published on 01 January 1990

Targeting of the Akt/PKB kinase to the actin skeleton.

scientific article published in December 2003

The Cutting Edge: The Role of mTOR Signaling in Laminopathies

scientific article published on 15 February 2019

The covalent binding of 1, 1,2,2-tetrachloroethane to macromolecules of rat and mouse organs

scientific article published on 01 January 1987

The different genotoxicity of p-dichlorobenzene in mouse and rat: measurement of the in vivo and in vitro covalent interaction with nucleic acids.

scientific article published in August 1989

The empowerment of translational research: lessons from laminopathies.

scientific article

The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence.

scientific article published on August 2016

Troglitazione affects survival of human osteosarcoma cells

scientific article published in March 2002

Ultrastructural aspects of the DNA polymerase alpha distribution during the cell cycle

scientific article

Ultrastructural defects of collagen VI filaments in an Ullrich syndrome patient with loss of the alpha3(VI) N10-N7 domains

scientific article published on 01 January 2006

Up-regulation of nuclear PLCbeta1 in myogenic differentiation

scientific article published on June 2003

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