List of works by Burkhard Jakob

ATM alters the otherwise robust chromatin mobility at sites of DNA double-strand breaks (DSBs) in human cells.

scientific article

ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control

scientific article

ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1.

scientific article published on 3 August 2015

Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage.

scientific article

Autophosphorylation and ATM activation: additional sites add to the complexity

scientific article

Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks

scientific article

Biological dose estimation of UVA laser microirradiation utilizing charged particle-induced protein foci

scientific article

Biological imaging of heavy charged-particle tracks

scientific article published in May 2003

CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response

scientific article

Clustered DNA damage induces pan-nuclear H2AX phosphorylation mediated by ATM and DNA-PK

scientific article published on 24 April 2013

Clustered double-strand breaks in heterochromatin perturb DNA repair after high linear energy transfer irradiation.

scientific article published on 13 September 2016

Correlative Light and Electron Microscopy (CLEM) Analysis of Nuclear Reorganization Induced by Clustered DNA Damage Upon Charged Particle Irradiation

scientific article published on 11 March 2020

DNA end resection is needed for the repair of complex lesions in G1-phase human cells

scientific article published on January 2014

Direct evidence for the spatial correlation between individual particle traversals and localized CDKN1A (p21) response induced by high-LET radiation.

scientific article

Immediate localized CDKN1A (p21) radiation response after damage produced by heavy-ion tracks

scientific article published on 01 October 2000

Induction and Processing of the Radiation-Induced Gamma-H2AX Signal and Its Link to the Underlying Pattern of DSB: A Combined Experimental and Modelling Study.

scientific article published on 11 June 2015

Live Cell Imaging to Study Real-Time ATM-Mediated Recruitment of DNA Repair Complexes to Sites of Ionizing Radiation-Induced DNA Damage

scientific article published in January 2017

Live cell imaging of heavy-ion-induced radiation responses by beamline microscopy.

scientific article published in June 2005

Live cell microscopy analysis of radiation-induced DNA double-strand break motion.

scholarly article

Nanoscale analysis of clustered DNA damage after high-LET irradiation by quantitative electron microscopy--the heavy burden to repair

scientific article published on 28 January 2015

PCNA-dependent accumulation of CDKN1A into nuclear foci after ionizing irradiation.

scientific article

Phosphorylation of Ku dictates DNA double-strand break (DSB) repair pathway choice in S phase

scientific article published on 27 December 2015

Positional stability of damaged chromatin domains along radiation tracks in mammalian cells

scientific article published in April 2009

Reduced contribution of thermally labile sugar lesions to DNA double strand break formation after exposure to heavy ions

scientific article published on 2 April 2013

Spatiotemporal dynamics of early DNA damage response proteins on complex DNA lesions

scientific article

Species conserved DNA damage response at the inactive human X chromosome

scientific article published on 28 April 2013

Targeted irradiation of Mammalian cells using a heavy-ion microprobe.

scientific article

X-ray irradiation activates K+ channels via H2O2 signaling

scientific article published on 9 September 2015

X-ray irradiation triggers immune response in human T-lymphocytes via store-operated Ca2+ entry and NFAT activation

scientific article published on 13 April 2022

pH and buffer capacities of apoplastic and cytoplasmic cell compartments in leaves.

scientific article