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List of works by Attila Ambrus

A direct and nondestructive approach to determine the folding structure of the I-motif DNA secondary structure by NMR.

scientific article published on May 2009

A labile regulatory copper ion lies near the T1 copper site in the multicopper oxidase CueO

scientific article

A multipronged approach unravels unprecedented protein-protein interactions in the human 2-oxoglutarate dehydrogenase multienzyme complex

scientific article published in Journal of Biological Chemistry

A re-evaluation of the role of matrix acidification in uncoupler-induced Ca2+ release from mitochondria.

scientific article

An Updated View on the Molecular Pathomechanisms of Human Dihydrolipoamide Dehydrogenase Deficiency in Light of Novel Crystallographic Evidence

scientific article published on 07 March 2019

Calcium binding of transglutaminases: a 43Ca NMR study combined with surface polarity analysis

scientific article published in August 2001

Crystal structures of the disease-causing D444V mutant and the relevant wild type human dihydrolipoamide dehydrogenase

scientific article published on 20 June 2018

DNA binding of sunitinib: Spectroscopic evidence via circular dichroism and nuclear magnetic resonance.

scientific article published on 16 December 2017

Diffusion-ordered nuclear magnetic resonance spectroscopy for analysis of DNA secondary structural elements

scientific article

Exclusive neuronal detection of KGDHC-specific subunits in the adult human brain cortex despite pancellular protein lysine succinylation

scientific article published on 25 January 2020

Formation of reactive oxygen species by human and bacterial pyruvate and 2-oxoglutarate dehydrogenase multienzyme complexes reconstituted from recombinant components

scientific article published on 8 October 2015

Human 2-oxoglutarate dehydrogenase complex E1 component forms a thiamin-derived radical by aerobic oxidation of the enamine intermediate

scientific article

Human dihydrolipoamide dehydrogenase (E3) deficiency: Novel insights into the structural basis and molecular pathomechanism

scientific article published on 2 June 2017

Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution

scientific article

Hydrogen-Deuterium Exchange Mass Spectrometry: A Novel Structural Biology Approach to Structure, Dynamics and Interactions of Proteins and Their Complexes

scientific article published on 15 November 2020

Inhibition of the alpha-ketoglutarate dehydrogenase-mediated reactive oxygen species generation by lipoic acid.

scientific article published in May 2009

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry protocol for monitoring the progress of enzymatic (13)C/(15)N-labeled DNA syntheses

scientific article

Measurement of ROS homeostasis in isolated mitochondria.

scientific article

Membrane potential and delta pH dependency of reverse electron transport-associated hydrogen peroxide production in brain and heart mitochondria

scientific article published on 17 August 2018

Molecular dynamics study of the structural basis of dysfunction and the modulation of reactive oxygen species generation by pathogenic mutants of human dihydrolipoamide dehydrogenase

scientific article published on 3 September 2013

Oligomerization of nitrophorins

scientific article published on 20 March 2006

Periplasmic cold expression and one-step purification of human dihydrolipoamide dehydrogenase

scientific article

Polyethylene glycol enhanced refolding of the recombinant human tissue transglutaminase

scientific article published in February 2001

Solution structure of the biologically relevant G-quadruplex element in the human c-MYC promoter. Implications for G-quadruplex stabilization

scientific article published in February 2005

Stimulation of reactive oxygen species generation by disease-causing mutations of lipoamide dehydrogenase

article

Structural alterations by five disease-causing mutations in the low-pH conformation of human dihydrolipoamide dehydrogenase (hLADH) analyzed by molecular dynamics - Implications in functional loss and modulation of reactive oxygen species generation

scientific article

Structural alterations induced by ten disease-causing mutations of human dihydrolipoamide dehydrogenase analyzed by hydrogen/deuterium-exchange mass spectrometry: Implications for the structural basis of E3 deficiency

scientific article

Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation

scientific article

Structure-function analyses of the G729R 2-oxoadipate dehydrogenase genetic variant associated with L-lysine metabolism disorder

scientific article published on 17 April 2020

TP53 mutation hits energy metabolism and increases glycolysis in breast cancer

scientific article

Total and semisynthesis and in vitro studies of both enantiomers of 20-fluorocamptothecin

scientific article

Triethylene glycol dimethacrylate impairs bioenergetic functions and induces oxidative stress in mitochondria via inhibiting respiratory Complex I.

scientific article published on 16 April 2018

Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants

scientific article published on 01 October 2019

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