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List of works by Janja Marc

-1227C>T polymorphism in the pleiotrophin gene promoter influences bone mineral density in postmenopausal women.

scientific article published on 3 February 2011

4th ESPT Conference: pharmacogenomics and personalized medicine - research progress and clinical implementation

scientific article published on 01 October 2019

4th ESPT summer school: precision medicine and personalised health

scientific article published on 01 May 2019

A microarray based identification of osteoporosis-related genes in primary culture of human osteoblasts

scientific article published on 23 September 2009

A transnational collaborative network dedicated to the study and applications of the vascular endothelial growth factor-A in medical practice: the VEGF Consortium

scientific article published on 01 March 2018

ADRA2A is involved in neuro-endocrine regulation of bone resorption

scientific article published on 27 March 2015

Activity or mass concentration of bone-specific alkaline phosphatase as a marker of bone formation

scientific article published on 01 January 2007

Analysis of Association of LRP5, LRP6, SOST, DKK1, and CTNNB1 Genes with Bone Mineral Density in a Slovenian Population

article

Analysis of CYP3A4*1B and CYP3A5*3 polymorphisms in population of Bosnia and Herzegovina.

scientific article published in February 2011

Antioxidant enzymes GSR, SOD1, SOD2, and CAT gene variants and bone mineral density values in postmenopausal women

article

Arsenic trioxide (ATO) influences the gene expression of metallothioneins in human glioblastoma cells.

scientific article published on 4 May 2012

Association between 11beta-hydroxysteroid dehydrogenase type 1 gene polymorphisms and metabolic syndrome in Bosnian population.

scientific article

Association of Dyslipidemia, Oxidative Stress, and Inflammation With Redox Status in VLDL, LDL, and HDL Lipoproteins in Patients With Renal Disease

scientific article published on 18 June 2018

Association of FTO Gene Variant (rs8050136) with Type 2 Diabetes and Markers of Obesity, Glycaemic Control and Inflammation

article

Association of NAT2 polymorphisms with type 2 diabetes in a population from Bosnia and Herzegovina.

scientific article published in May 2011

Association of PPARG and LPIN1 gene polymorphisms with metabolic syndrome and type 2 diabetes

article

Association of TNFSF11 gene promoter polymorphisms with bone mineral density in postmenopausal women.

scientific article

Association of the osteoprotegerin gene polymorphisms with bone mineral density in postmenopausal women.

scientific article

Association of vitamin D receptor gene polymorphism with bone mineral density in Slovenian postmenopausal women

scientific article published on 01 February 2000

Atorvastatin treatment increases plasma bilirubin but not HMOX1 expression in stable angina patients

scientific article published on 29 April 2015

BMD values and GSTM3 gene polymorphisms in combination with GSTT1/GSTM1 genes: a genetic association study in Slovenian elderly.

scientific article published on 8 February 2012

Bone microRNAs and aging

scientific article published on 2 February 2017

CTSS activation coexists with CD40 activation in human atheroma: evidence from plasma mRNA analysis.

scientific article

Cathepsin K predicts femoral neck bone mineral density change in nonosteoporotic peri- and early postmenopausal women

scientific article published on 01 March 2008

Codon 325 sequence polymorphism of the estrogen receptor alpha gene and bone mineral density in postmenopausal women

scientific article published on 01 July 2001

Decreased lipin 1 beta expression in visceral adipose tissue is associated with insulin resistance in polycystic ovary syndrome

scientific article published in October 2008

Development and validation of a liquid chromatography–tandem mass spectrometry assay for determination of raloxifene and its metabolites in human plasma

article

Effect of cetirizine, a histamine (H(1)) receptor antagonist, on bone modeling during orthodontic tooth movement in rats.

scientific article

Effects of UGT1A1*28 polymorphism on raloxifene pharmacokinetics and pharmacodynamics

scientific article published on April 2009

Effects of melatonin receptor 1B gene variation on glucose control in population from Bosnia and Herzegovina.

scientific article published on 7 April 2014

Epigenetic enzymes influenced by oxidative stress and hypoxia mimetic in osteoblasts are differentially expressed in patients with osteoporosis and osteoarthritis

scientific article published in Scientific Reports

Epigenetic mechanisms in bone

scientific article published on May 2014

Etidronate does not suppress periprosthetic bone loss following cemented hip arthroplasty.

scientific article

Exonic, but not intronic polymorphisms of ESR1 gene might influence the hypolipemic effect of raloxifene

article

Expression of 11β-hydroxysteroid dehydrogenase type 1 in visceral and subcutaneous adipose tissues of patients with polycystic ovary syndrome is associated with adiposity

scientific article published on 13 December 2010

Expression of bone resorption genes in osteoarthritis and in osteoporosis

article

Frequencies of Q188R and N314D Mutations and IVS5-24G>A Intron Variation in the Galactose-1-Phosphate Uridyl Transferase (GALT) Gene in the Slovenian Population

article

Genetic effects on bone health

article

Gene–gene interactions in RANK/RANKL/OPG system influence bone mineral density in postmenopausal women

article

Genome-wide gene expression profiling of low-dose, long-term exposure of human osteosarcoma cells to bisphenol A and its analogs bisphenols AF and S.

scientific article published on 22 April 2015

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

scientific article

Highlights from the latest pharmacogenomic genome-wide association studies

scientific article published in March 2013

Human Skeletal Muscle-Derived Mesenchymal Stem/Stromal Cell Isolation and Growth Kinetics Analysis

scientific article published on 01 January 2019

Hypoxia mimetic deferoxamine influences the expression of histone acetylation- and DNA methylation-associated genes in osteoblasts.

scientific article

Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density

scientific article

Impact of metformin and rosiglitazone treatment on glucose transporter 4 mRNA expression in women with polycystic ovary syndrome

scientific article

Implementation of a companion diagnostic in the clinical laboratory: the BRAF example in melanoma.

scientific article published on 23 October 2014

Increased Apolipoprotein E Gene Expression and Protein Concentration in Lung Cancer Tissue Do Not Contribute to the Clinical Assessment of Non-small Cell Lung Cancer Patients

scientific article published on 01 October 2008

Increased DAPK1 but decreased CCL2 plasma levels of nucleic acids in patients with stable angina.

scientific article

Increased Plasma Cathepsin s at the Time of Percutaneous Transluminal Angioplasty is Associated with 6-months' Restenosis of the Femoropopliteal Artery.

scientific article

Increased bone resorption in HD patients: is it caused by elevated RANKL synthesis?

scientific article published on 21 January 2005

Increased levels of osteoprotegerin in hemodialysis patients

scientific article published in October 2002

Increased lipoprotein lipase activity in non-small cell lung cancer tissue predicts shorter patient survival

scientific article published on 25 July 2009

Increased phosphatidylethanolamine N-methyltransferase gene expression in non-small-cell lung cancer tissue predicts shorter patient survival.

scientific article

Increased plasma levels of CATS mRNA but not CATB mRNA in patients with coronary atherosclerosis

scientific article published on 27 September 2010

Influence of hepatic and intestinal efflux transporters and their genetic variants on the pharmacokinetics and pharmacodynamics of raloxifene in osteoporosis treatment

scientific article published on 28 March 2012

Influence of trypsinization and alternative procedures for cell preparation before RNA extraction on RNA integrity.

scientific article published on 28 June 2014

Interleukin-1α gene variants influence bone mineral density and the risk of osteoporotic hip fractures in elderly Slovenian people

article

Interrelated cathepsin S-lowering and LDL subclass profile improvements induced by atorvastatin in the plasma of stable angina patients.

scientific article published on 14 April 2014

Inverse correlation of carotid intima-media thickness with raloxifene serum levels in osteoporosis

scientific article published on 20 May 2014

Is laboratory medicine ready for the era of personalized medicine? A survey addressed to laboratory directors of hospitals/academic schools of medicine in Europe

scientific article published on 01 June 2015

Is laboratory medicine ready for the era of personalized medicine? A survey addressed to laboratory directors of hospitals/academic schools of medicine in Europe.

scientific article

LIPOPROTEIN LIPASE ACTIVITY AND GENE EXPRESSION IN LUNG CANCER AND IN ADJACENT NONCANCER LUNG TISSUE

article

Lipin 1 gene polymorphisms in polycystic ovary syndrome.

scientific article published on 29 March 2011

Lipoprotein lipase in non-small cell lung cancer tissue is highly expressed in a subpopulation of tumor-associated macrophages

scientific article

Mercury speciation in prenatal exposure in Slovenian and Croatian population - PHIME study

scientific article published on 05 August 2019

Mesenchymal Stem Cells in the Musculoskeletal System: From Animal Models to Human Tissue Regeneration?

scientific article published on 20 March 2018

MiR-148a the epigenetic regulator of bone homeostasis is increased in plasma of osteoporotic postmenopausal women.

scientific article published on 29 November 2016

Molecular mechanisms of insulin resistance and associated diseases

scientific article

Monitoring of imatinib targeted delivery in human leukocytes.

scientific article published on 2 May 2013

New insights into adipose tissue dysfunction in insulin resistance

scientific article published on 06 September 2011

No major effect of estrogen receptor beta gene RsaI polymorphism on bone mineral density and response to alendronate therapy in postmenopausal osteoporosis

scientific article

Opposite effects of GSTM1--and GSTT1: gene deletion variants on bone mineral density.

scientific article published on January 2011

Optimisation of methods for quantifying plasma mRNA levels from genes responsible for coronary artery plaque development and destabilization.

scientific article

Optimization of high-resolution melting analysis for simultaneous genotyping of two 11β-hydroxysteroid dehydrogenase type 1 gene polymorphisms.

scientific article

Optimization of single-stranded conformation polymorphism (SSCP) analysis for screening for the estrogen receptor-alpha gene polymorphism P325P.

scientific article published in July 2001

Organic anion transporting polypeptides OATP1B1 and OATP1B3 and their genetic variants influence the pharmacokinetics and pharmacodynamics of raloxifene

scientific article

Osteoarthritic versus osteoporotic bone and intra-skeletal variations in normal bone: evaluation with µCT and bone histomorphometry.

scientific article

Osteoblastogenesis and adipogenesis are higher in osteoarthritic than in osteoporotic bone tissue.

scientific article

Osteoimmunology and the influence of pro-inflammatory cytokines on osteoclasts

scientific article

Osteoporosis pharmacogenomics: recent insights and future perspectives

scientific article published in April 2013

P4 medicine and osteoporosis: a systematic review.

scientific article published on 21 November 2016

PPARG gene promoter polymorphism is associated with non-traumatic hip fracture risk in the elderly Slovenian population: A pilot study

article

Personalized laboratory medicine: a patient-centered future approach

scientific article published on 01 November 2018

Pharmacogenomics education in medical and pharmacy schools: conclusions of a global survey

scientific article published on 01 June 2019

Prenatal mercury exposure, neurodevelopment and apolipoprotein E genetic polymorphism.

scientific article published on 8 September 2016

Preparation of reference material for UGT1A1 (TA)n polymorphism genotyping

scientific article published on 29 April 2014

Raloxifene pharmacodynamics is influenced by genetic variants in the RANKL/RANK/OPG system and in the Wnt signaling pathway

scientific article published on January 2014

Report from the European Society of Pharmacogenomics and Theranostics (ESPT) Inaugural Symposium 2011 in Bled

scientific article published on 01 January 2012

Risk factors for symptomatic osteonecrosis in childhood ALL: A retrospective study of a Slovenian pediatric ALL population between 1970 and 2004.

scientific article published on 25 May 2016

Sequence variations in the osteoprotegerin gene promoter in patients with postmenopausal osteoporosis.

scientific article published in September 2002

Sex-determining region Y (SRY) attributes to gender differences in RANKL expression and incidence of osteoporosis

scientific article published on 14 August 2019

Skeletal-muscle-derived mesenchymal stem/stromal cells from patients with osteoarthritis show superior biological properties compared to bone-derived cells

scientific article published on 14 May 2019

Sub-therapeutic doses of fluvastatin and valsartan are more effective than therapeutic doses in providing beneficial cardiovascular pleiotropic effects in rats: A proof of concept study.

scientific article published on 23 September 2017

TNFRSF11B gene polymorphisms 1181G > C and 245T > G as well as haplotype CT influence bone mineral density in postmenopausal women.

scientific article

Testing GSTP1 genotypes and haplotypes interactions in Slovenian post-/pre-menopausal women: Novel involvement of glutathione S-transferases in bone remodeling process

scientific article published on 03 January 2012

The "Rise-Peak-Fall" Pattern of Time Dependency of the Cardiovascular Pleiotropic Effects of Treatment With Low-dose Atorvastatin, Losartan, and a Combination Thereof in Rats

scientific article published in July 2016

The Pleiotropic Effects of Atorvastatin on Stable Angina Patients: Evidence by Analysis of High-Density Lipoprotein Size and Subclasses, and Plasma mRNA.

scientific article published on 14 July 2015

The antioxidant enzyme GPX1 gene polymorphisms are associated with low BMD and increased bone turnover markers.

scientific article published on January 2010

The combinations of polymorphisms in vitamin D receptor, osteoprotegerin and tumour necrosis factor superfamily member 11 genes are associated with bone mineral density

scientific article published on 8 January 2009

The impact of gene polymorphisms in angiotensin receptor 1 and aldosterone synthase in peritoneal dialysis patients

scientific article published on 01 January 2017

The low-dose atorvastatin and valsartan combination effectively protects the arterial wall from atherogenic diet-induced impairment in the guinea pig.

scientific article

The many faces of estrogen signaling.

scientific article

The relationship between osteoclastogenic and anti-osteoclastogenic pro-inflammatory cytokines differs in human osteoporotic and osteoarthritic bone tissues

scientific article published in March 2012

The role of artichoke leaf tincture (Cynara scolymus) in the suppression of DNA damage and atherosclerosis in rats fed an atherogenic diet.

scientific article published in December 2018

Treatment with low-dose atorvastatin, losartan, and their combination increases expression of vasoactive-related genes in rat aortas

scientific journal article

Triglyceride metabolism in bone tissue is associated with osteoblast and osteoclast differentiation: a gene expression study

scientific article published on 16 April 2013

Tumour necrosis factor superfamily member 11 gene promoter polymorphisms modulate promoter activity and influence bone mineral density in postmenopausal women with osteoporosis

scientific article published in June 2008

VDR genotype and response to etidronate therapy in late postmenopausal women

scientific article published on 01 January 1999

VEGF-A is associated with early degenerative changes in cartilage and subchondral bone

scientific article published on 01 December 2018

Vitamin D receptor gene polymorphism and bone metabolism during low-dose oral contraceptive use in young women

scientific article

XbaI polymorphism of the estrogen receptor alpha gene influences the effect of raloxifene on the endothelial function

scientific article published on 6 July 2010