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List of works by Alexander Combes

A spatially-averaged mathematical model of kidney branching morphogenesis.

scientific article published on 24 April 2015

An integrated pipeline for the multidimensional analysis of branching morphogenesis

scientific article published on 20 November 2014

Analysed cap mesenchyme track data from live imaging of mouse kidney development.

scientific article

Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment

scientific article published on 6 June 2009

Bayesian inference of agent-based models: a tool for studying kidney branching morphogenesis

scientific article published in February 2018

Branching morphogenesis in the developing kidney is not impacted by nephron formation or integration

scientific article published on 31 July 2018

Cap mesenchyme cell swarming during kidney development is influenced by attraction, repulsion, and adhesion to the ureteric tip.

scientific article published on 23 June 2016

Cell-cell interactions driving kidney morphogenesis

scientific article

Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome

scientific journal article

Endothelial cell migration directs testis cord formation

scientific article published on 7 November 2008

Epigenetic reprogramming: enforcer or enabler of developmental fate?

scientific article published on August 2010

Epigenetics and developmental programming of adult onset diseases

scientific article published on December 2012

Ex vivo magnetofection: a novel strategy for the study of gene function in mouse organogenesis

scientific article

Expression and functional analysis of Dkk1 during early gonadal development.

scientific article

Global quantification of tissue dynamics in the developing mouse kidney

scientific article

Gonadal defects in Cited2-mutant mice indicate a role for SF1 in both testis and ovary differentiation

scientific article published in January 2010

Hamartin regulates cessation of mouse nephrogenesis independently of Mtor

scientific article published on 21 May 2018

Haploinsufficiency for the Six2 gene increases nephron progenitor proliferation promoting branching and nephron number

scientific article published on 4 December 2017

Identification of novel hypomorphic and null mutations in Klf1 derived from a genetic screen for modifiers of α-globin transgene variegation

scientific article published on 31 October 2014

Luminal mitosis drives epithelial cell dispersal within the branching ureteric bud

scientific article

MicroRNAs-140-5p/140-3p modulate Leydig cell numbers in the developing mouse testis

scientific article published on 6 June 2013

Modelling cell turnover in a complex tissue during development.

scientific article published on 7 September 2013

Neonatal vascularization and oxygen tension regulate appropriate perinatal renal medulla/papilla maturation

scientific article

Nephron formation adopts a novel spatial topology at cessation of nephrogenesis

scientific article published on 21 September 2011

Nephron progenitor commitment is a stochastic process influenced by cell migration

scholarly article by Kynan T Lawlor et al published 24 January 2019 in eLife

Pisrt1, a gene implicated in XX sex reversal, is expressed in gonads of both sexes during mouse development

scientific article

Polarity, cell division, and out-of-equilibrium dynamics control the growth of epithelial structures

scientific article published on 21 October 2013

ROBO2 restricts the nephrogenic field and regulates Wolffian duct-nephrogenic cord separation

scientific article

SOX9 regulates prostaglandin D synthase gene transcription in vivo to ensure testis development

scientific article published on 2 February 2007

Segmental territories along the cardinal veins generate lymph sacs via a ballooning mechanism during embryonic lymphangiogenesis in mice

scientific article

Self-organisation after embryonic kidney dissociation is driven via selective adhesion of ureteric epithelial cells.

scientific article published on 7 February 2017

Sex Determination and Gonadal Development

article

Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk

scientific article published on 12 June 2019

Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development

scientific article

Towards a quantitative model of kidney morphogenesis

scientific article

Understanding kidney morphogenesis to guide renal tissue regeneration.

scientific article

Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment

scientific article published on 05 December 2018