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List of works by Mario Scartozzi

5-Fluorouracil pharmacogenomics: still rocking after all these years?

scientific article published on February 2011

A combination of gefitinib and FOLFOX-4 as first-line treatment in advanced colorectal cancer patients. A GISCAD multicentre phase II study including a biological analysis of EGFR overexpression, amplification and NF-kB activation

scientific article published on 4 December 2007

Adenocarcinoma arising from ileoanal J-pouch mucosa

scientific article published on 06 April 2011

Adjuvant Treatment After Surgical Resection

Allele polymorphisms of tumor integrins correlate with peritoneal carcinosis capability of gastric cancer cells in radically resected patients

scientific article published on 06 October 2010

Analysis of HER-3, insulin growth factor-1, nuclear factor-kB and epidermal growth factor receptor gene copy number in the prediction of clinical outcome for K-RAS wild-type colorectal cancer patients receiving irinotecan-cetuximab.

scientific article published on 23 November 2011

Anemia may influence the outcome of patients undergoing neo-adjuvant treatment of rectal cancer

scientific article published on 12 September 2006

Angiogenesis Genotyping and Clinical Outcomes in Patients with Advanced Hepatocellular Carcinoma Receiving Sorafenib: The ALICE-2 Study

scientific article published on 01 February 2020

Angiogenesis genotyping and clinical outcome during regorafenib treatment in metastatic colorectal cancer patients.

scientific article published on 27 April 2016

Angiogenesis genotyping in the selection of first-line treatment with either sunitinib or pazopanib for advanced renal cell carcinoma.

scientific article published on 09 May 2016

Angiogenetic pathway as a therapeutic target in renal cell carcinoma

scientific article published on 01 February 2012

Anti-EGFR strategies as an incremental step for the treatment of colorectal cancer patients: moving from scientific evidence to clinical practice.

scientific article

Arterial hypertension correlates with clinical outcome in colorectal cancer patients treated with first-line bevacizumab

scientific article

Basal and bevacizumab-based therapy-induced changes of lactate dehydrogenases and fibrinogen levels and clinical outcome of previously untreated metastatic colorectal cancer patients: a multicentric retrospective analysis.

scientific article

Beyond RAS: the role of epidermal growth factor receptor (EGFR) and its network in the prediction of clinical outcome during anti-EGFR treatment in colorectal cancer patients

scientific article

COX-2 and NF-KB overexpression is common in pancreatic cancer but does not predict for COX-2 inhibitors activity in combination with gemcitabine and oxaliplatin.

scientific article published in October 2007

Cancer stem cell gene profile as predictor of relapse in high risk stage II and stage III, radically resected colon cancer patients

scientific article

Cetuximab plus gemcitabine and cisplatin compared with gemcitabine and cisplatin alone in patients with advanced pancreatic cancer: a randomised, multicentre, phase II trial

scientific article published in January 2008

Cetuximab rechallenge in metastatic colorectal cancer patients: how to come away from acquired resistance?

scientific article published on 5 March 2012

Chemotherapy-free intervals in patients with metastatic colorectal cancer: a tale of two cities?

scientific article published on 12 April 2010

Clinical evidence for three distinct gastric cancer subtypes: time for a new approach

scientific article

Clinical predictive factors for advanced non-small cell lung cancer (NSCLC) patients receiving third-line therapy: Selecting the unselectable?

scientific article published on 6 August 2009

Clinical significance and treatment of skin rash from erlotinib in non-small cell lung cancer patients: results of an Experts Panel Meeting.

scientific article

Colorectal Cancer Early Detection in Stool Samples Tracing CpG Islands Methylation Alterations Affecting Gene Expression

scientific article published on 24 June 2020

Combined analysis of E-cadherin gene (CDH1) promoter hypermethylation and E-cadherin protein expression in patients with gastric cancer: implications for treatment with demethylating drugs.

scientific article published in March 2004

Contemporary best practice in the management of urothelial carcinomas of the renal pelvis and ureter

scientific article published on 08 January 2019

Correction to: Angiogenesis Genotyping and Clinical Outcomes in Patients with Advanced Hepatocellular Carcinoma Receiving Sorafenib: The ALICE‑2 Study

scientific article published on 10 November 2020

Dalotuzumab, a recombinant humanized mAb targeted against IGFR1 for the treatment of cancer.

scientific article published on June 2010

Elderly patients with advanced non-small cell lung cancer. A pase II study with weekly cisplatin and gemcitabine

scientific article

Epidermal Growth Factor Receptor (EGFR) gene copy number (GCN) correlates with clinical activity of irinotecan-cetuximab in K-RAS wild-type colorectal cancer: a fluorescence in situ (FISH) and chromogenic in situ hybridization (CISH) analysis

scientific article published on 27 August 2009

Epidermal growth factor receptor (EGFR) downstream signalling pathway in primary colorectal tumours and related metastatic sites: optimising EGFR-targeted treatment options.

scientific article published on 19 June 2007

Epidermal growth factor receptor (EGFR) gene promoter methylation and cetuximab treatment in colorectal cancer patients.

scientific article

Epidermal growth factor receptor (EGFR) status in primary colorectal tumors does not correlate with EGFR expression in related metastatic sites: implications for treatment with EGFR-targeted monoclonal antibodies.

scientific article published in December 2004

Evolving strategies for the treatment of hepatocellular carcinoma: from clinical-guided to molecularly-tailored therapeutic options.

scientific article published on 25 August 2010

First-line FOLFIRI and bevacizumab in patients with advanced colorectal cancer prospectively stratified according to serum LDH: final results of the GISCAD (Italian Group for the Study of Digestive Tract Cancers) CENTRAL (ColorEctalavastiNTRiAlLdh)

scientific article published on 19 September 2017

From CENTRAL to SENTRAL (SErum aNgiogenesis cenTRAL): Circulating Predictive Biomarkers to Anti-VEGFR Therapy

scientific article published on 22 May 2020

Hepatocellular carcinoma treatment over sorafenib: epigenetics, microRNAs and microenvironment. Is there a light at the end of the tunnel?

scientific article published on 27 July 2015

High curative resection rate with weekly cisplatin, 5-fluorouracil, epidoxorubicin, 6S-leucovorin, glutathione, and filgastrim in patients with locally advanced, unresectable gastric cancer: a report from the Italian Group for the Study of Digestive

scientific article

Insulin-like growth factor 1 expression correlates with clinical outcome in K-RAS wild type colorectal cancer patients treated with cetuximab and irinotecan.

scientific article published in October 2010

Lactate Dehydrogenase in Hepatocellular Carcinoma: Something Old, Something New

scientific article

Liver metastases from colorectal cancer

scientific article published on 01 April 1997

Locally Advanced Rectal Cancer Patients Receiving Radio-Chemotherapy: A Novel Clinical–Pathologic Score Correlates With Global Outcome

scientific article published on 20 April 2009

Locally advanced rectal cancer: from molecular profiling to clinical practice. A literature review: Part 2.

scientific article published on October 2009

Locoregional treatments of unresectable liver metastases from colorectal cancer

scientific article published on 01 February 1998

Loss of hMLH1 expression correlates with improved survival in stage III-IV ovarian cancer patients

scientific article published in May 2003

Metronomic chemotherapy from rationale to clinical studies: a dream or reality?

scientific article published on 20 January 2015

Mismatch repair deficiency may affect clinical outcome through immune response activation in metastatic gastric cancer patients receiving first-line chemotherapy.

scientific article published on 21 January 2016

Mismatch repair system (MMR) status correlates with response and survival in non-small cell lung cancer (NSCLC) patients

scientific article published in July 2006

Molecular biology for stage II colorectal cancer: the jury is still out

scientific article published on 01 July 2007

Molecular biology of sporadic gastric cancer: prognostic indicators and novel therapeutic approaches.

scientific article published in August 2004

Molecular biomarkers of resistance to anti-EGFR treatment in metastatic colorectal cancer, from classical to innovation

scientific article published on 24 June 2013

Multidisciplinary treatment of locally advanced rectal cancer: a literature review. Part 1.

scientific article published on October 2009

Mutations of hMLH1 and hMSH2 in patients with suspected hereditary nonpolyposis colorectal cancer: correlation with microsatellite instability and abnormalities of mismatch repair protein expression

scientific article published on 01 March 2002

Natural history of malignant bone disease in hepatocellular carcinoma: final results of a multicenter bone metastasis survey.

scientific article

Neutrophil-to-lymphocyte ratio may be associated with the outcome in patients with prostate cancer.

scientific article

New target therapies in advanced pancreatic cancer.

scientific article published on May 2006

Novel perspectives for the treatment of gastric cancer: from a global approach to a personalized strategy.

scientific article published in May 2010

Nuclear Factor-kB Tumor Expression Predicts Response and Survival in Irinotecan-Refractory Metastatic Colorectal Cancer Treated With Cetuximab-Irinotecan Therapy

article

Off-target effects and clinical outcome in metastatic colorectal cancer patients receiving regorafenib: The TRIBUTE analysis

scientific article published on 05 April 2017

Outcomes of Advanced Gastric Cancer Patients Treated with at Least Three Lines of Systemic Chemotherapy

scientific article published in February 2018

Outcomes of Advanced Gastric Cancer Patients Treated with at Least Three Lines of Systemic Chemotherapy.

scientific article published on 31 August 2017

Over-DI dissection may question the value of radiotherapy as a part of an adjuvant programme in high-risk radically resected gastric cancer patients.

scientific article published on March 2005

PTEN expression and KRAS mutations on primary tumors and metastases in the prediction of benefit from cetuximab plus irinotecan for patients with metastatic colorectal cancer.

scientific article published on 27 April 2009

Pancreatic cancer: progress in cancer therapy.

scientific article published on 19 March 2008

Pegylated liposomal doxorubicin, 5-fluorouracil and cisplatin versus mitomycin-C, 5-fluorouracil and cisplatin for advanced gastric cancer: a randomized phase II trial

scientific article

Perioperative anemia and blood transfusions as prognostic factors in patients undergoing resection for non-small cell lung cancers

scientific article published on 01 September 2005

Perspectives from American Society of Clinical Oncology: translational and clinical research highlights in breast and colorectal cancers.

scientific article published in October 2014

Pharmacogenomics of cetuximab in metastatic colorectal carcinoma.

scientific article

Phase II study of pharmacogenetic-tailored therapy in elderly colorectal cancer patients

scientific article published on 03 September 2011

Phosphorylated AKT and MAPK expression in primary tumours and in corresponding metastases and clinical outcome in colorectal cancer patients receiving irinotecan-cetuximab

scientific article

Pre-operative treatment modalities in gastric cancer patients.

scientific article

Pre-treatment lactate dehydrogenase levels as predictor of efficacy of first-line bevacizumab-based therapy in metastatic colorectal cancer patients ⬇️

scientific article published on February 7, 2012

Predictive and prognostic role of E-cadherin protein expression in patients with advanced gastric carcinomas treated with palliative chemotherapy.

scientific article published in May 2004

Predictive factors for sunitinib treatment response in advanced renal cell carcinoma: are we really making steps forward?

scientific article published on 01 February 2015

Profiling tumor-associated markers for early detection of malignant mesothelioma: an epidemiologic study

scientific article

Prognostic Role ofInterleukin-1βGene andInterleukin-1 Receptor AntagonistGene Polymorphisms in Patients With Advanced Gastric Cancer

article

Prognostic Value for Incidental Antihypertensive Therapy With β-Blockers in Metastatic Colorectal Cancer.

scientific article

Prognostic Value of Thyroid Hormone Ratios in Patients With Advanced Metastatic Colorectal Cancer Treated With Regorafenib: The TOREADOR Study

scientific article published on 08 June 2018

Prognostic clinical factors in pretreated colorectal cancer patients receiving regorafenib: implications for clinical management

scientific article published on 17 August 2015

Prognostic factors in 868 advanced gastric cancer patients treated with second-line chemotherapy in the real world.

scientific article published on 27 December 2016

Prognostic impact of mismatch repair genes germline defects in colorectal cancer patients: are all mutations equal?

scientific article published on 15 October 2015

Prospective study of a molecular selection profile for RAS wild type colorectal cancer patients receiving irinotecan-cetuximab

scientific article published on 7 May 2015

Recent aspects of sunitinib therapy in patients with metastatic clear-cell renal cell carcinoma: a systematic review of the literature

scientific article

Renal Function Outcomes in Metastatic Non-Small-Cell Lung Carcinoma Patients Treated with Chemotherapy or Immune Checkpoint Inhibitors: An Unexpected Scenario

scientific article published on 24 April 2022

Role and mechanisms of resistance of epidermal growth factor receptor antagonists in the treatment of colorectal cancer.

scientific article published on 04 June 2015

Role of vascular endothelial growth factor (VEGF) and VEGF-R genotyping in guiding the metastatic process in pT4a resected gastric cancer patients

scientific article

Role of β4 integrin in HER-3-negative, K-RAS wild-type metastatic colorectal tumors receiving cetuximab

scientific article

Second-line angiogenesis inhibition in metastatic colorectal cancer patients: Straightforward or overcrowded?

scientific article published on 12 February 2016

Second-line chemotherapy with irinotecan, 5-fluorouracil and leucovorin (FOLFIRI) in relapsed or metastatic gastric cancer: lessons from clinical practice

scientific article

Selected gastrointestinal cancer presentations from the American Society of Clinical Oncology annual meeting 2013 in review: it is not about the destination, it is about the journey

scientific article

Selected news from the 2014 Genitourinary Cancers Symposium: translating novel strategies into clinical practice.

scientific article published in November 2014

Selecting patients for gastrectomy in metastatic esophago-gastric cancer: clinics and pathology are not enough.

scientific article published on 4 October 2017

State of the art and future perspectives for the use of insulin-like growth factor receptor 1 (IGF-1R) targeted treatment strategies in solid tumors

scientific article published on February 1, 2011

Survival in patients with clear cell renal cell carcinoma is predicted by HIF-1α expression.

scientific article published on January 2015

Systemic therapy for the treatment of endometrial cancer

scientific article published on 26 August 2019

The "angiogenetic ladder", step-wise angiogenesis inhibition in metastatic colorectal cancer.

scientific article published on 20 June 2014

The Immune Revolution in Gastrointestinal Tumours: Leading the Way or Just Following?

scientific article published on 17 May 2016

The PANDA study: a randomized phase II study of first-line FOLFOX plus panitumumab versus 5FU plus panitumumab in RAS and BRAF wild-type elderly metastatic colorectal cancer patients.

scientific article published on 25 January 2018

The Role of Aspirin as Antitumoral Agent for Heavily Pretreated Patients With Metastatic Colorectal Cancer Receiving Capecitabine Monotherapy

scientific article published on 04 August 2016

The Tower of Babel of liver metastases from colorectal cancer: are we ready for one language?

scientific article published on 08 September 2012

The challenge of targeted therapies for gastric cancer patients: the beginning of a long journey

scientific article published on 07 May 2014

The correlation between LDH serum levels and clinical outcome in advanced biliary tract cancer patients treated with first line chemotherapy.

scientific article published on 11 April 2016

The distinctive molecular, pathological and clinical characteristics of BRAF-mutant colorectal tumors

scientific article published on 15 May 2015

The response of breast cancer cells to mesenchymal stem cells: a possible role of inflammation by breast implants.

scientific article published on December 2013

The role of 5-fluorouracil (5-FU) reintroduction with irinotecan or oxaliplatin in truly 5-FU-refractory advanced colorectal cancer patients

scientific article published on 7 July 2005

The role of HER-3 expression in the prediction of clinical outcome for advanced colorectal cancer patients receiving irinotecan and cetuximab.

scientific article published on 6 January 2011

The role of LDH serum levels in predicting global outcome in HCC patients treated with sorafenib: implications for clinical management

scientific article published on 20 February 2014

The role of LDH serum levels in predicting global outcome in HCC patients undergoing TACE: implications for clinical management

scientific article

The role of micro-RNAs in hepatocellular carcinoma: from molecular biology to treatment.

scientific article published on 19 May 2014

The role of primary tumour sidedness, EGFR gene copy number and EGFR promoter methylation in RAS/BRAF wild-type colorectal cancer patients receiving irinotecan/cetuximab.

scientific article published on 20 June 2017

The timing of surgery for resectable metachronous liver metastases from colorectal cancer: Better sooner than later? A retrospective analysis

scientific article published on 21 August 2010

The value of lactate dehydrogenase serum levels as a prognostic and predictive factor for advanced pancreatic cancer patients receiving sorafenib.

scientific article published on 10 September 2015

Three drugs vs two drugs first-line chemotherapy regimen in advanced gastric cancer patients: a retrospective analysis.

scientific article published on December 2015

Toward molecularly selected chemotherapy for advanced gastric cancer: state of the art and future perspectives.

scientific article published on 20 May 2009

Tracking the 2015 Gastrointestinal Cancers Symposium: bridging cancer biology to clinical gastrointestinal oncology

scientific article

Trans-arterial chemo-embolization (TACE), with either lipiodol (traditional TACE) or drug-eluting microspheres (precision TACE, pTACE) in the treatment of hepatocellular carcinoma: efficacy and safety results from a large mono-institutional analysis

scientific article

Translational challenges from the 2014 Gastrointestinal Cancers Symposium: toward a true tailored therapy through effective research

scientific article

Treatment sequence with either irinotecan/cetuximab followed by FOLFOX-4 or the reverse strategy in metastatic colorectal cancer patients progressing after first-line FOLFIRI/bevacizumab: An Italian Group for the Study of Gastrointestinal Cancer pha

scientific article published on 20 July 2017

Tumor VEGF expression correlates with tumor stage and identifies prognostically different groups in patients with clear cell renal cell carcinoma

scientific article

Tumor angiogenesis genotyping and efficacy of first-line chemotherapy in metastatic gastric cancer patients

scientific article

Tumor infiltrating lymphocytes in gastrointestinal tumors: Controversies and future clinical implications

scientific article published on 25 November 2016

VEGF and VEGFR genotyping in the prediction of clinical outcome for HCC patients receiving sorafenib: the ALICE-1 study

scientific article published on 20 February 2014

Women and lung cancer: clinical and molecular profiling as a determinate for treatment decisions: a literature review.

scientific article published on 22 August 2008

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